Label: 3M SOLUPREP S- chlorhexidine gluconate and isopropyl alcohol solution

Drug Facts

Chlorhexidine gluconate 2% w/v

Isopropyl alcohol 70% v/v

Antiseptic

Antiseptic

patient preoperative skin preparation:

• for preparation of the skin prior to surgery
• helps reduce bacteria that potentially can cause skin infection

For external use only. Flammable, keep away from fire or flame.

To reduce risk of fire, PREP CAREFULLY:

• do not use 26-mL applicator for head and neck surgery
• do not use on an area smaller than 8.4 in. x 15.6 in. Use a smaller applicator instead.
• solution contains alcohol and gives off flammable vapors
• avoid getting solution into hairy areas. Wet hair is flammable. Hair may take up to 1 hour to dry.
• do not drape or use ignition source (e.g., cautery, laser) until solution is completely dry (minimum of 3 minutes on hairless skin; up to 1 hour in hair)
• do not allow solution to pool
• remove wet materials from prep area

• use with care in premature infants or infants under 2 months of age. These products may cause irritation or chemical burns.
• discard the applicator after a single use along with any portion of the solution not required to cover the prepped area. It is not necessary to use the entire amount available.

Getting Patient Ready for Solution:

• use in well-ventilated area
• do not microwave or heat the solution applicator
• apply to clean, completely dry, residue-free, intact skin
• when hair removal is necessary, use a surgical clipper on the morning of the surgery. If a wet shave is used, thoroughly remove all soap residues.

Activating the Applicator:

• remove applicator from package; do not touch sponge
• with sponge face parallel to the floor, press the cap end of the applicator. Solution will begin to flow into sponge.

When Applying Solution:

• completely wet the treatment area with antiseptic
• dry surgical sites (e.g., abdomen or arm): use repeated back-and-forth strokes for 30 seconds
• moist surgical sites (e.g., inguinal fold): use repeated back-and-forth strokes for 2 minutes
• maximal treatment area for one applicator is approximately 13.2 in. x 21.6 in. (285.2 in2).
• do not allow solution to pool; tuck prep towels to absorb solution, and then remove
• clean umbilicus with enclosed swabs when applicable.
• (Moisten swabs by pressing against solution-soaked sponge applicator.)
• avoid getting solution into hairy areas. Wet hair is flammable. Hair may take up to 1 hour to dry.
• when prepping skin folds, toes, or fingers, use a sterile-gloved hand to hold skin apart until completely dry.

After Applying Solution:

• to reduce the risk of fire, wait until solution is completely dry (minimum of 3 minutes on hairless skin; up to 1 hour in hair)

While Waiting for Solution to Completely Dry:

• do not drape or use ignition source (e.g., cautery, laser)
• check for pooled solution. Use sterile gauze to soak up pooled solution. Do not blot because it may remove solution from skin.
• remove wet materials from prep area. Replace if necessary.

After Solution is Completely Dry:

• to reduce the risk of fire, begin draping and/or using cautery only after solution is completely dry and all wet materials are removed
• if incise drapes are used, apply directly to dry prep
• apply dressing following standard practices

• store between 15-30 °C (59-86 °F)
• avoid freezing and excessive heat above 40 °C (104 °F)
• The tint will slowly fade from the skin. For early removal of surgical prep use soap and water or 70% Isopropyl Alcohol.

acetyltri-n-butyl citrate, FD&C blue #1, FD&C yellow #5, purified water USP, Trisodium HEDTA

call 1-800-228-3957 (Monday-Friday 7AM-6PM CST). www.3M.com/Medical

34-8727-1905-8

Drug Facts

Chlorhexidine gluconate 2% w/v

Isopropyl alcohol 70% v/v

Antiseptic

Antiseptic

patient preoperative skin preparation:

• for preparation of the skin prior to surgery
• helps reduce bacteria that potentially can cause skin infection

For external use only. Flammable, keep away from fire or flame.

To reduce risk of fire, PREP CAREFULLY:

• solution contains alcohol and gives off flammable vapors
• avoid getting solution into hairy areas. Wet hair is flammable. Hair may take up to 1 hour to dry.
• do not drape or use ignition source (e.g., cautery, laser) until solution is completely dry (minimum of 3 minutes on hairless skin; up to 1 hour in hair)
• do not allow solution to pool
• remove wet materials from prep area

• use with care in premature infants or infants under 2 months of age. These products may cause irritation or chemical burns.
• discard the applicator after a single use along with any portion of the solution not required to cover the prepped area. It is not necessary to use the entire amount available.

Getting Patient Ready for Solution:

• use in well-ventilated area
• do not microwave or heat the solution applicator
• apply to clean, completely dry, residue-free, intact skin
• when hair removal is necessary, use a surgical clipper on the morning of the surgery. If a wet shave is used, thoroughly remove all soap residues.

Activating the Applicator:

• remove applicator from package; do not touch sponge
• grasp products by wrapping hand and fingers around the labeled portion of the applicator. Place thumb on the lever with sponge face parallel to the floor, snap lever to allow fluid to flow into sponge.

When Applying Solution:

• completely wet the treatment area with antiseptic
• dry surgical sites (e.g., abdomen or arm): use repeated back-and-forth strokes for 30 seconds
• moist surgical sites (e.g., inguinal fold): use repeated back-and-forth strokes for 2 minutes
• maximal treatment area for one applicator is approximately 8.4 in. x 15.6 in. (131.4 in2).
• do not allow solution to pool; tuck prep towels to absorb solution, and then remove
• avoid getting solution into hairy areas. Wet hair is flammable. Hair may take up to 1 hour to dry.
• when prepping skin folds, toes, or fingers, use a sterile-gloved hand to hold skin apart until completely dry.

After Applying Solution:

• to reduce the risk of fire, wait until solution is completely dry (minimum of 3 minutes on hairless skin; up to 1 hour in hair)

While Waiting for Solution to Completely Dry:

• do not drape or use ignition source (e.g., cautery, laser)
• check for pooled solution. Use sterile gauze to soak up pooled solution. Do not blot because it may remove solution from skin.
• remove wet materials from prep area. Replace if necessary.

After Solution is Completely Dry:

• to reduce the risk of fire, begin draping and/or using cautery only after solution is completely dry and all wet materials are removed
• if incise drapes are used, apply directly to dry prep
• apply dressing following standard practices

• store between 15-30 °C (59-86 °F)
• avoid freezing and excessive heat above 40 °C (104 °F)
• The tint will slowly fade from the skin. For early removal of surgical prep use soap and water or 70% Isopropyl Alcohol.

acetyltri-n-butyl citrate, FD&C blue #1, FD&C yellow #5, purified water USP, Trisodium HEDTA

call 1-800-228-3957 (Monday-Friday 7AM-6PM CST). www.3M.com/Medical

34-8727-1906-6

Drug Facts

Chlorhexidine gluconate 2% w/v

Isopropyl alcohol 70% v/v

Antiseptic

Antiseptic

patient preoperative skin preparation:

• for preparation of the skin prior to surgery
• helps reduce bacteria that potentially can cause skin infection

• For external use only. Flammable, keep away from fire or flame.
• To reduce risk of fire, PREP CAREFULLY:
• solution contains alcohol and gives off flammable vapors
• avoid getting solution into hairy areas. Wet hair is flammable. Hair may take up to 1 hour to dry.
• do not drape or use ignition source (e.g., cautery, laser) until solution is completely dry (minimum of 3 minutes on hairless skin; up to 1 hour in hair)
• do not allow solution to pool
• remove wet materials from prep area

• use with care in premature infants or infants under 2 months of age. These products may cause irritation or chemical burns.
• discard the applicator after a single use along with any portion of the solution not required to cover the prepped area. It is not necessary to use the entire amount available.

Getting Patient Ready for Solution:

• use in well-ventilated area
• do not microwave or heat the solution applicator
• apply to clean, completely dry, residue-free, intact skin
• when hair removal is necessary, use a surgical clipper on the morning of the surgery. If a wet shave is used, thoroughly remove all soap residues.

Activating the Applicator:

• remove applicator from package; do not touch sponge
• grasp product by wrapping hand and fingers around the labeled portion of the applicator. Place thumb on the lever with sponge face parallel to the floor, snap lever to allow fluid to flow into sponge.

When Applying Solution:

• completely wet the treatment area with antiseptic
• dry surgical sites (e.g., abdomen or arm): use repeated back-and-forth strokes for 30 seconds
• moist surgical sites (e.g., inguinal fold): use repeated back-and-forth strokes for 2 minutes
• maximal treatment area for one applicator is approximately 8.4 in. x 15.6 in. (131.4 in2)
• do not allow solution to pool; tuck prep towels to absorb solution, and then remove
• avoid getting solution into hairy areas. Wet hair is flammable. Hair may take up to 1 hour to dry.
• when prepping skin folds, toes, or fingers, use a sterile-gloved hand to hold skin apart until completely dry.

After Applying Solution:

• to reduce the risk of fire, wait until solution is completely dry (minimum of 3 minutes on hairless skin; up to 1 hour in hair)

While Waiting for Solution to Completely Dry:

• do not drape or use ignition source (e.g., cautery, laser)
• check for pooled solution. Use sterile gauze to soak up pooled solution. Do not blot because it may remove solution from skin.
• remove wet materials from prep area. Replace if necessary.

After Solution is Completely Dry:

• to reduce the risk of fire, begin draping and/or using cautery only after solution is completely dry and all wet materials are removed
• if incise drapes are used, apply directly to dry prep
• apply dressing following standard practices

• store between 15-30 °C (59-86 °F)
• avoid freezing and excessive heat above 40 °C (104 °F)

acetyltri-n-butyl citrate, purified water USP, Trisodium HEDTA

call 1-800-228-3957 (Monday-Friday 7AM-6PM CST). www.3M.com/Medical

34-8727-1907-4

3M

NDC 17518-082-01

STERILE EO

SoluPrep™ S

chlorhexidine gluconate (2% w/v) and isopropyl alcohol (70% v/v)

Patient Preoperative Skin Preparation

REF 67130

for large prep areas below the neck

Sterile Antiseptic Solution

Applicator is sterile if package is intact

Brite Green

0.9 fl oz • 26 mL

Single Use

Only

PRESS CAP DOWN

BACK AND FORTH

APPLICATION

External use only

Professional use only

Read Drug Facts information

before use

34-8727-1931-4

3M and SoluPrep are trademarks of 3M.

3M

STERILE EO

NDC 17518-082-01

SoluPrep™ S

chlorhexidine gluconate (2% w/v) and isopropyl alcohol (70% v/v)

Patient Preoperative Skin Preparation

for large prep areas below the neck

Sterile Antiseptic Solution

Applicator is sterile if package is intact

Brite Green

SoluPrep™ S Sterile Antiseptic Solution is a sterile patient preoperative skin preparation.

Each unit dose applicator contains 0.9 fl oz (26 mL) of solution which covers a 13.2 in. x 21.6 in. area (approximate from shoulder to groin in an average full size adult).

For procedures requiring less coverage, a smaller applicator is available (67133 - Tinted or

67134 - Clear). The smaller applicator size contains 0.36 fl oz (10.5 mL) of solution which

covers an approximate 8.4 in. x 15.6 in. area. Do not use more than required for the area.

3M recommends all users participate in product in-service training prior to use.

In-servicing is available on video, from your 3M sales representative or at the 3M website

(www.3m.com).

SoluPrep™ S Sterile Antiseptic Solution is an antimicrobial skin preparation. It is

recommended that the prep remain on the skin after the procedure for continued

protection. The prep will gradually wear away. If however early removal is desired, use

soap and water or 70% isopropyl alcohol.

REF 67130

0.9 fl oz • 26 mL

Made in USA with Globally

Sourced Materials

3M Company

2510 Conway Ave.

St. Paul, MN 55144 USA

1-800-228-3957

www.3M.com/Medical

Single Use Only

3M and SoluPrep are trademarks of 3M.

@ 2022, 3M. All rights reserved.

Not Made With

Natural Rubber Latex

34-8727-1932-2

3M

REF 67130

NDC 17518-082-01

Single

Use Only

SoluPrep™ S

chlorhexidine gluconate (2% w/v) and isopropyl alcohol (70% v/v)

Patient Preoperative Skin Preparation

for large prep areas below the neck

Sterile Antiseptic Solution

Applicator is sterile if package is intact

0.9 fl oz • 26 mL

Brite Green

3M

NDC 17518-082-02

STERILE EO

SoluPrep™ S

chlorhexidine gluconate (2% w/v) and isopropyl alcohol (70% v/v)

Patient Preoperative Skin Preparation

REF 67133

for head, neck, and small prep areas

Sterile Antiseptic Solution

Applicator is sterile if package is intact

Brite Green

0.36 fl oz • 10.5 mL

Single Use

Only

3M and

SoluPrep

are trademarks

of 3M.

SNAP

BACK AND FORTH

APPLICATION

External use only

Professional use only

Read Drug Facts information

before use

34-8727-1930-6

3M

STERILE EO

NDC 17518-082-02

SoluPrep™ S

chlorhexidine gluconate

(2% w/v) and isopropyl

alcohol (70% v/v)

Patient Preoperative Skin Preparation

for head, neck, and small prep areas

Sterile Antiseptic Solution

Applicator is sterile if package is intact

Brite Green

SoluPrep™ S Sterile Antiseptic Solution is a sterile

patient preoperative skin preparation. Each unit dose

applicator contains 0.36 fl oz (10.5 mL) of solution which

covers a 8.4 in. x 15.6 in. area.

3M recommends all users participate in product

in-service training prior to use. In-servicing is available

on video, from your 3M sales representative or at the 3M

website (www.3m.com).

SoluPrep™ S Sterile Antiseptic Solution is an

antimicrobial skin preparation. It is recommended that

the prep remain on the skin after the procedure for

continued protection. The prep will gradually wear away.

If however early removal is desired, use soap and water

or 70% isopropyl alcohol.

REF 67133

0.36 fl oz • 10.5 mL

Made in USA with Globally

Sourced Materials

3M Company

2510 Conway Ave.

St. Paul, MN 55144 USA

1-800-228-3957

www.3M.com/Medical

3M and SoluPrep are

trademarks of 3M.

@ 2022, 3M. All rights reserved.

34-8727-1933-0

3M

REF 67133

NDC 17518-082-02

Single

Use Only

SoluPrep™ S

chlorhexidine gluconate (2% w/v) and isopropyl alcohol (70% v/v)

Patient Preoperative Skin Preparation

for head, neck, and small prep areas

Sterile Antiseptic Solution

Applicator is sterile if package is intact

0.36 fl oz • 10.5 mL

Brite Green

3M

NDC 17518-083-02

STERILE EO

SoluPrep™ S

chlorhexidine gluconate (2% w/v) and isopropyl alcohol (70% v/v)

Patient Preoperative Skin Preparation

REF 67134

for head, neck, and small prep areas

Sterile Antiseptic Solution

Applicator is sterile if package is intact

Clear

0.36 fl oz • 10.5 mL

SNAP

BACK AND FORTH

APPLICATION

External use only

Professional use only

Read Drug Facts information

before use

Single Use

Only

3M and

SoluPrep

are trademarks

of 3M.

34-8727-1929-8

3M

STERILE EO

NDC 17518-083-02

SoluPrep™ S

chlorhexidine gluconate

(2% w/v) and isopropyl

alcohol (70% v/v)

Patient Preoperative Skin Preparation

for head, neck, and small prep areas

Sterile Antiseptic Solution

Applicator is sterile if package is intact

Clear

Not Made With

Natural Rubber Latex

Single Use Only

SoluPrep™ S Sterile Antiseptic Solution is a sterile

patient preoperative skin preparation. Each unit dose

applicator contains 0.36 fl oz (10.5 mL) of solution which

covers a 8.4 in. x 15.6 in. area.

3M recommends all users participate in product

in-service training prior to use. In-servicing is available

on video, from your 3M sales representative or at the 3M

website (www.3m.com).

SoluPrep™ S Sterile Antiseptic Solution is an

antimicrobial skin preparation. It is recommended that

the prep remain on the skin after the procedure for

continued protection. The prep will gradually wear away.

If however early removal is desired, use soap and water or 70% isopropyl

alcohol.

REF 67134

0.36 fl oz • 10.5 mL

Made in USA with Globally

Sourced Materials

3M Company

2510 Conway Ave.

St. Paul, MN 55144 USA

1-800-228-3957

www.3M.com/Medical

3M and SoluPrep are trademarks of 3M.

@ 2022, 3M. All rights reserved.

34-8727-1934-8

3M

REF 67134

NDC 17518-083-02

Single

Use Only

SoluPrep™ S

chlorhexidine gluconate (2% w/v) and isopropyl alcohol (70% v/v)

Patient Preoperative Skin Preparation

for head, neck, and small prep areas

Sterile Antiseptic Solution

Applicator is sterile if package is intact

0.36 fl oz • 10.5 mL

Clear