SPL RESOURCES: Download All Drug Labels

Choose from daily, weekly or monthly periodic updates or full releases of all drug labels. Downloads are available as zip files.

Periodic Updates

MONTHLY WEEKLY DAILY

• dm_spl_monthly_update_mar2025.zip [ HTTPS / FTP ]
  • Number of labels: 4,123
  • File size: 1.54GB
  • MD5 checksum: 2c373bb6cd92c4183b0d9171be77a45f
• dm_spl_monthly_update_feb2025.zip [ HTTPS / FTP ]
  • Number of labels: 4,031
  • File size: 1.56GB
  • MD5 checksum: 4cf1ce490c973cde084dab422ee5fb23
• dm_spl_monthly_update_jan2025.zip [ HTTPS / FTP ]
  • Number of labels: 7,670
  • File size: 2.58GB
  • MD5 checksum: 3974bb282aaa814ace053fc498ae8135
• dm_spl_monthly_update_dec2024.zip [ HTTPS / FTP ]
  • Number of labels: 10,396
  • File size: 3.58GB
  • MD5 checksum: ab23a7acda78af9de1a5367c461a55de
• dm_spl_monthly_update_nov2024.zip [ HTTPS / FTP ]
  • Number of labels: 8,038
  • File size: 2.67GB
  • MD5 checksum: a198163c8fae036fb8855d4b9f2a7fbf
• dm_spl_monthly_update_oct2024.zip [ HTTPS / FTP ]
  • Number of labels: 9,801
  • File size: 256.25MB
  • MD5 checksum: b8211ed1d91638e5315e5af4e8785c32
• dm_spl_monthly_update_sep2024.zip [ HTTPS / FTP ]
  • Number of labels: 4,493
  • File size: 1.39GB
  • MD5 checksum: 055959e7063e05c73e2aa56f6cf0aa8a
• dm_spl_weekly_update_042125_042525.zip [ HTTPS / FTP ]
  • Number of labels: 632
  • File size: 237.40MB
  • MD5 checksum: 2be209a0db4081f6abd92678fe4013a1
• dm_spl_weekly_update_041425_041825.zip [ HTTPS / FTP ]
  • Number of labels: 835
  • File size: 352.63MB
  • MD5 checksum: 14df27c3bbe6047d8f6d678a690aac32
• dm_spl_weekly_update_040725_041125.zip [ HTTPS / FTP ]
  • Number of labels: 1,266
  • File size: 456.26MB
  • MD5 checksum: 3703a3771f250d3fedf630422921c04d
• dm_spl_weekly_update_033125_040425.zip [ HTTPS / FTP ]
  • Number of labels: 901
  • File size: 293.53MB
  • MD5 checksum: 328897cdb98cca41cc40b0ef2a2fea58
• dm_spl_daily_update_04282025.zip [ HTTPS / FTP ]
  • Number of labels: 402
  • File size: 176.62MB
  • MD5 checksum: 807587f274389b97ae1c9bbde76c76fe

Full Releases

Warning: The full human prescription and OTC archive files, dm_spl_release_human_rx.zip and dm_spl_release_human_otc.zip, are no longer available due to size considerations. Instead, these archives have been split into multiple parts. The remainder archive files consist of bulk ingredient labels, vaccine labels, and some labels for medical devices.

HUMAN PRESCRIPTION LABELS HUMAN OTC LABELS HOMEOPATHIC LABELS ANIMAL LABELS REMAINDER LABELS

• dm_spl_release_human_rx_part1.zip [ HTTPS / FTP ]
  • Number of files: 15,100
  • File size: 3.00GB
  • MD5 checksum: 914bb94c1603cce1cfaba8517c5d7825
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_rx_part2.zip [ HTTPS / FTP ]
  • Number of files: 10,518
  • File size: 3.00GB
  • MD5 checksum: 037f60956280e3f7c0976d9cdfc96e82
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_rx_part3.zip [ HTTPS / FTP ]
  • Number of files: 9,158
  • File size: 3.00GB
  • MD5 checksum: fcd8febe36fe890538e2893fe7925506
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_rx_part4.zip [ HTTPS / FTP ]
  • Number of files: 9,287
  • File size: 3.00GB
  • MD5 checksum: 37cb818f35063630edd07796d0e43885
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_rx_part5.zip [ HTTPS / FTP ]
  • Number of files: 6,551
  • File size: 2.34GB
  • MD5 checksum: f832fbd48cbd5a6a16ef7414e65393c4
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_otc_part1.zip [ HTTPS / FTP ]
  • Number of files: 12,272
  • File size: 3.00GB
  • MD5 checksum: c1c612376cc276c4f8cf1057d78c1917
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_otc_part2.zip [ HTTPS / FTP ]
  • Number of files: 8,943
  • File size: 3.00GB
  • MD5 checksum: 23c875082ee0575f310474744314405b
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_otc_part3.zip [ HTTPS / FTP ]
  • Number of files: 6,306
  • File size: 3.00GB
  • MD5 checksum: fbebae844a881ac3c5f302814244f0a6
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_otc_part4.zip [ HTTPS / FTP ]
  • Number of files: 6,076
  • File size: 3.00GB
  • MD5 checksum: 07367ff21af9339b1d9431c7cb761bce
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_otc_part5.zip [ HTTPS / FTP ]
  • Number of files: 7,390
  • File size: 3.00GB
  • MD5 checksum: 4f990d11a1b9e6bcba388f79bf27afb2
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_otc_part6.zip [ HTTPS / FTP ]
  • Number of files: 7,374
  • File size: 3.00GB
  • MD5 checksum: 10ccb9bdbb119c25728624339f7d7a57
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_otc_part7.zip [ HTTPS / FTP ]
  • Number of files: 8,361
  • File size: 3.00GB
  • MD5 checksum: d2c5c30212cdc469542904a5dd7463ee
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_otc_part8.zip [ HTTPS / FTP ]
  • Number of files: 10,124
  • File size: 3.00GB
  • MD5 checksum: 310660cb5aec2ed960c446566fe6e0ec
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_otc_part9.zip [ HTTPS / FTP ]
  • Number of files: 8,488
  • File size: 3.00GB
  • MD5 checksum: d1c5bb9b8b7065f3971efea5c8dd2dee
  • Last Modified: Apr 28, 2025
• dm_spl_release_human_otc_part10.zip [ HTTPS / FTP ]
  • Number of files: 6,641
  • File size: 2.56GB
  • MD5 checksum: 10261471ddac151e80d107f2ead5b365
  • Last Modified: Apr 28, 2025
• dm_spl_release_homeopathic.zip [ HTTPS / FTP ]
  • Number of files: 15,823
  • File size: 5.29GB
  • MD5 checksum: 91e1db11462ecde0dab9c9caee6edd34
  • Last Modified: Apr 28, 2025
• dm_spl_release_animal.zip [ HTTPS / FTP ]
  • Number of files: 3,285
  • File size: 1.01GB
  • MD5 checksum: b1481067d4c33787d0b7ed90e69efcca
  • Last Modified: Apr 28, 2025
• dm_spl_release_remainder.zip [ HTTPS / FTP ]
  • Number of files: 2,269
  • File size: 541.66MB
  • MD5 checksum: b27b59f83b34bd4844d311840baa0fee
  • Last Modified: Apr 28, 2025