Label: ALKA-SELTZER ORIGINAL FLAVOR tablet, effervescent

  • NDC Code(s): 0280-0087-01, 0280-0087-02, 0280-0087-03, 0280-0087-04, view more
    0280-0087-06
  • Packager: Bayer HealthCare LLC.
  • Category: HUMAN OTC DRUG LABEL
  • DEA Schedule: None

Drug Label Information

Updated December 4, 2025

If you are a consumer or patient please visit this version.

  • ACTIVE INGREDIENT

    Active ingredient (in each tablet)

    Buffered aspirin 325 mg (NSAID)*

  • PURPOSE

    Pain reliever/fever reducer

    *nonsteroidal anti-inflammatory drug

  • INDICATIONS & USAGE

    Uses

    ● temporarily relieves minor aches and pains due to:

    ● headache ● muscle pain ● backache

    ● toothache ● menstrual pain ● colds

    ● minor pain of arthritis

    ● temporarily reduces fever

  • WARNINGS

    Warnings

    Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness.

    Allergy alert: Aspirin may cause a severe allergic reaction which may include:

    · hives · facial swelling · asthma (wheezing) · shock

    Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is

    higher if you

    ● are age 60 or older

    ● have had stomach ulcers or bleeding problems

    ● take a blood thinning (anticoagulant) or steroid drug

    ● take other drugs containing prescription or nonprescription

    NSAIDs (aspirin, ibuprofen, naproxen, or others)

    ● have 3 or more alcoholic drinks every day while using this

    product

    ● take more or for a longer time than directed

  • DO NOT USE



    Do not use

    ● if you are allergic to aspirin or any other pain reliever/fever reducer

    ● if you have ever had an allergic reaction to this product or any of its ingredients

  • ASK DOCTOR

    Ask a doctor before use if

    ● stomach bleeding warning applies to you

    ● you have a history of stomach problems, such as heartburn

    ● you have high blood pressure, heart disease, liver cirrhosis, or kidney disease

    ● you are taking a diuretic

    ● you have asthma

    ● you have a sodium-restricted diet

  • ASK DOCTOR/PHARMACIST

    Ask a doctor or pharmacist before use if you are taking a prescription drug for

    ● diabetes ● gout ● arthritis

  • STOP USE

    Stop use and ask a doctor if

    ● an allergic reaction occurs. Seek medical help right away.

    ● you experience any of the following signs of stomach bleeding:

    ● feel faint ● vomit blood ● have bloody or black stools

    ● have stomach pain that does not get better

    ● pain gets worse or last more than 10 days

    ● fever gets worse or last more than 3 days

    ● redness or swelling is present

    ● new symptoms occur

    ● ringing in the ears or a loss of hearing occurs

  • PREGNANCY OR BREAST FEEDING

    If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

  • KEEP OUT OF REACH OF CHILDREN

    Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

  • DOSAGE & ADMINISTRATION

    Directions

    ● fully dissolve 2 tablets in 4 ounces of water before taking

    adults and children 12 years and over2 tablets every 4 hours, or as directed by a doctordo not exceed 8 tablets in 24 hours
    adults 60 years and over2 tablets every 4 hours, or as directed by a doctordo not exceed 4 tablets in 24 hours
    children under 12 yearsconsult a doctor

  • OTHER SAFETY INFORMATION

    Other information

    each tablet contains: sodium 568 mg

    ● store at room temperature. Avoid excessive heat.

    ● Alka-Seltzer Original Flavor in water contains principally the analgesic sodium acetylsalicylate

  • INACTIVE INGREDIENT

    Inactive Ingredients anhydrous citric acid, sodium bicarbonate

  • QUESTIONS

    Questions or comments?1-800-986-0369 (Mon – Fri 9AM – 5PM EST)

  • PRINCIPAL DISPLAY PANEL

    Alka-Seltzer Original Flavor 24ct

    Alka-Seltzer

    Buffered Aspirin (NSAID) / Pain reliever / fever reducer

    Fast Relief of:
    Headache
    Backache
    Body Aches
    Muscle Pain

    ORIGINAL FLAVOR

    24 EFFERVESCENT TABLETS

    (12 - 2 count pouches)

  • INGREDIENTS AND APPEARANCE
    ALKA-SELTZER ORIGINAL FLAVOR 
    alka-seltzer original flavor tablet, effervescent
    Product Information
    Product TypeHUMAN OTC DRUGItem Code (Source)NDC:0280-0087
    Route of AdministrationORAL
    Active Ingredient/Active Moiety
    Ingredient NameBasis of StrengthStrength
    ASPIRIN (UNII: R16CO5Y76E) (ASPIRIN - UNII:R16CO5Y76E) ASPIRIN325 mg
    Inactive Ingredients
    Ingredient NameStrength
    ANHYDROUS CITRIC ACID (UNII: XF417D3PSL) 1000 mg
    SODIUM BICARBONATE (UNII: 8MDF5V39QO) 1916 mg
    Product Characteristics
    ColorwhiteScoreno score
    ShapeROUNDSize25mm
    FlavorImprint Code Alka;Seltzer
    Contains    
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:0280-0087-0412 in 1 CARTON03/03/2022
    12 in 1 POUCH; Type 0: Not a Combination Product
    2NDC:0280-0087-0218 in 1 CARTON03/03/2022
    22 in 1 POUCH; Type 0: Not a Combination Product
    3NDC:0280-0087-0336 in 1 CARTON04/04/2022
    32 in 1 POUCH; Type 0: Not a Combination Product
    4NDC:0280-0087-016 in 1 CARTON04/18/2023
    42 in 1 POUCH; Type 0: Not a Combination Product
    5NDC:0280-0087-0658 in 1 CARTON04/26/2023
    52 in 1 POUCH; Type 0: Not a Combination Product
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    OTC Monograph DrugM01303/03/2022
    Labeler - Bayer HealthCare LLC. (112117283)