Label: CARBON DIOXIDE REFRIGERATED- carbon dioxide gas

  • NDC Code(s): 52438-014-20, 52438-014-21
  • Packager: Messer LLC
  • Category: HUMAN PRESCRIPTION DRUG LABEL
  • DEA Schedule: None
  • Marketing Status: New Drug Application

Drug Label Information

Updated February 16, 2026

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  • PRINCIPAL DISPLAY PANEL

    MESSER Gases for Life

    Bulk Carbon Dioxide USP Certificate of Analysis

    This is to certify that the carbon dioxide tested at MESSER PLANT on 10/27/2025, meets the United States Pharmacopoeia (USP) specifications, the requirements of Federal Specifications BB-C-101 Grade A and QVL E of CGA G6.2. This product was manufactured at a facility registered with the Federal Food and Drug Administration and is approved for prescription drug use. This product is not guaranteed to meet any other specification or intended for pesticide use. NDA 205764 NADA 141362

    Furthermore, batch number 5784-A-102725-01, and lot number TCO2002-102725-13, which was loaded on 10/27/2025 and produced at MESSER PLANT comprises this shipment and was analyzed as shown below.

    Analytical results are generated using USP monograph or validated equivalent methods.

    FOR MEDICAL USE

    Requirement Analytical Method Limit of Detection Specification Limit Result

    Carbon Dioxide Assay (CO2) Speed of Sound 99.99 % 99.0 % 99.99%

    Nitrogen Oxide (NO) IMR-MS 0.05 ppm 2.5 ppm ND

    Nitrogen Dioxide (NO2) IMR-MS 0.1 ppm 2.5 ppm ND

    Ammonia (NH3) IMR-MS 0.03 ppm 25 ppm ND

    Sulfur Dioxide (SO2) IMR-MS 0.03 ppm 5 ppm ND

    Hydrogen Sulfide (H2S) IMR-MS 0.03 ppm 1 ppm ND

    Carbon Monoxide (CO) FTIR 0.05 ppm 10 ppm ND

    Moisture (H2O) Quartz Crystal 0.5 ppm 200 ppm 0.77 ppm

    Notes:

    Positive Carbon Dioxide Identification is achieved when the Assay results demonstrate meeting the specification.
    The limit of detection (LOD) for each test method is the threshold value for results to be reported with certainty in the accuracy of results. A test result outside the detection limit for the test method will be reported as ND.
    ND = None Detected
    ppm = parts per million by volume, ppb = parts per billion by volume, 1 ppm = 1,000 ppb

    Product analyzed using Messer Ultra Guard Suite

    Certified By:

    (Signature) (Date)

    John Doe
    (Print Name & Title)

    On behalf of Messer LLC CO2 GENERIC COA NEW TEMPLATE

  • INGREDIENTS AND APPEARANCE
    CARBON DIOXIDE REFRIGERATED 
    carbon dioxide gas
    Product Information
    Product TypeHUMAN PRESCRIPTION DRUGItem Code (Source)NDC:52438-014
    Route of AdministrationRESPIRATORY (INHALATION)
    Active Ingredient/Active Moiety
    Ingredient NameBasis of StrengthStrength
    CARBON DIOXIDE (UNII: 142M471B3J) (CARBON DIOXIDE - UNII:142M471B3J) CARBON DIOXIDE990 mL  in 1 L
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:52438-014-2018770 L in 1 TANK; Type 0: Not a Combination Product01/01/1965
    2NDC:52438-014-2159 L in 1 CYLINDER; Type 0: Not a Combination Product01/01/196512/31/2025
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    NDANDA20576401/01/1965
    Labeler - Messer LLC (001368141)
    Registrant - Messer LLC (001368141)
    Establishment
    NameAddressID/FEIBusiness Operations
    Messer LLC004830011manufacture(52438-014) , api manufacture(52438-014)
    Establishment
    NameAddressID/FEIBusiness Operations
    Messer LLC020153345manufacture(52438-014) , api manufacture(52438-014)
    Establishment
    NameAddressID/FEIBusiness Operations
    Messer LLC833150639manufacture(52438-014) , api manufacture(52438-014)