Label: EQUATE CHILDRENS MULTI SYMPTOM COLD NIGHTTIME- acetaminophen, diphenhydramine hcl, phenylephrine hcl liquid

  • Category: HUMAN OTC DRUG LABEL
  • DEA Schedule: None
  • Marketing Status: OTC monograph final

DISCLAIMER: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

Drug Label Information

Updated November 28, 2022

If you are a consumer or patient please visit this version.

  • ACTIVE INGREDIENTS (in each 10 mL)

    Acetaminophen 325 mg

    Diphenhydramine HCl 12.5 mg

    Phenyephrine HCl 5 mg

  • PURPOSE

    Pain reliever / fever reducer

    Antihistamine/Cough Suppressant

    Nasal decongestant

  • USE(S)

    temporarily relieves these common cold and flu symptoms:

    • cough 
    • sore throat
    • nasal congestion
    • runny nose
    • minor aches and pains
    • headache
    • sinus congestion and pressure
    • sneezing
    • temporarily reduces fever
    • controls cough to help your child get to sleep
  • WARNINGS

    Liver warning: This product contains acetaminophen. Severe liver damage may occur if your child takes 


    • more than 5 doses in 24 hous, which is the maximum daily amount
    • with other drugs containing acetaminophen.

    Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:


    • skin reddening
    • blisters
    • rash

    If a skin reaction occurs, stop use and seek medical help right away

    Sore throat warning: if sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea or vomiting, consult a doctor promptly. 

  • DO NOT USE

    • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
    • to make a child sleepy
    • with any other product containing diphenhydramine, even one used on the skin.
    • in a child who is taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your child's prescription drug contains an MAOI, ask a doctor or pharmacist before giving this product.
  • ASK A DOCTOR BEFORE USE IF THE CHILD HAS

    • liver disease
    • thyroid disease
    • diabetes
    • heart disease
    • high blood pressure
    • glaucoma
    • a breathing problem such as chronic bronchitis
    • persistent or chronic cough such as occurs with asthma
    • cough that occurs with too much phlegm (mucus)
  • ASK A DOCTOR OR PHARMACIST BEFORE USE IF YOUR CHILD 

    • is taking the blood thinning drug warfarin
    • taking sedatives or tranquilizers
  • WHEN USING THIS PRODUCT

    • do not use more than directed (see Overdose warning)
    • excitability may occur, especially in children
    • marked drowsiness may occur
    • sedatives and tranquilizers may increase dowsiness
  • STOP USE AND ASK DOCTOR IF

    • nervousness, dizziness or sleeplessness occur
    • pain, nasal congestion or cough gets worse or lasts more than 5 days
    • fever gets worse or lasts more than 3 days
    • redness or swelling is present
    • new symptoms occur
    • cough comes back, or occurs with rash or headache that lasts. These could be signs of a serious condition.
  • KEEP OUT OF REACH OF CHILDREN

    Overdose warning: Taking more than the recommended dose (overdose) may cause liver damage. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical even if you do not notice any signs or symptoms.

  • DIRECTIONS

    • this product does not contain directions or complete warnings for adult use
    • do not give more than directed (see Overdose warning)
    • shake well before use
    • do not give more than 5 doses in any 24-hour period
    • if needed, repeat dose every 4 hours while symptoms last
    • do not give more than 5 days unless directed by a doctor
    • measure only with dosing cup provided
    • do not use dosing cup with other products
    • dose as follows or as directed by a doctor
    • mL = milliliter
    • Children 6 to under 12 years of age: 10 mL in dosing cup provided.
    • Children under 6 years of age: do not use.
  • OTHER INFORMATION

    • each 10 mL contains: sodium 10 mg
    • store between 15-30°C (59-86°F)
    • do not refrigerate
    • dosing cup provided
  • INACTIVE INGREDIENTS

    citric acid anhydrous, edetate disodium, FD&C blue #1, FD&C red #40, flavors, glycerin, propylene glycol, propyl gallate, purified water, sodium benzoate, sodium citrate, sorbitol, sucralose, xanthan gum.


  • QUESTIONS OR COMMENTS

    1-888-287-1915

  • PRINCIPAL DISPLAY PANEL

    NDC 49035-623-03

    equate

    Compare to Children's Mucinex® Nighttime Multi-Symptom Cold active ingredients*

    Children's 

     MULTI-SYMPTOMS COLD 
    NIGHTTIME

    Acetaminophen 325 mg
    Pain reliever/Fever Reducer

    Diphenhydramine HCl 12.5 mg

    Antihistamine/Cough Suppressant 

    Phenylephrine HCl 5 mg

    Nasal Decongestant

    AGES 6 to 12 YEARS



    • Relieves headache and fever
    • Soothes cough
    • Relieves nasal congestion 
    • Relieves runny nose and sneezing

     Mixed Berry Flavored



     4 FL OZ (118 mL)

    623-Equate-4oz


  • INGREDIENTS AND APPEARANCE
    EQUATE CHILDRENS MULTI SYMPTOM COLD NIGHTTIME 
    acetaminophen, diphenhydramine hcl, phenylephrine hcl liquid
    Product Information
    Product TypeHUMAN OTC DRUGItem Code (Source)NDC:49035-623
    Route of AdministrationORAL
    Active Ingredient/Active Moiety
    Ingredient NameBasis of StrengthStrength
    ACETAMINOPHEN (UNII: 362O9ITL9D) (ACETAMINOPHEN - UNII:362O9ITL9D) ACETAMINOPHEN325 mg  in 10 mL
    DIPHENHYDRAMINE HYDROCHLORIDE (UNII: TC2D6JAD40) (DIPHENHYDRAMINE - UNII:8GTS82S83M) DIPHENHYDRAMINE HYDROCHLORIDE12.5 mg  in 10 mL
    PHENYLEPHRINE HYDROCHLORIDE (UNII: 04JA59TNSJ) (PHENYLEPHRINE - UNII:1WS297W6MV) PHENYLEPHRINE HYDROCHLORIDE5 mg  in 10 mL
    Inactive Ingredients
    Ingredient NameStrength
    ANHYDROUS CITRIC ACID (UNII: XF417D3PSL)  
    EDETATE DISODIUM (UNII: 7FLD91C86K)  
    FD&C BLUE NO. 1 (UNII: H3R47K3TBD)  
    FD&C RED NO. 40 (UNII: WZB9127XOA)  
    GLYCERIN (UNII: PDC6A3C0OX)  
    PROPYLENE GLYCOL (UNII: 6DC9Q167V3)  
    PROPYL GALLATE (UNII: 8D4SNN7V92)  
    WATER (UNII: 059QF0KO0R)  
    SODIUM BENZOATE (UNII: OJ245FE5EU)  
    SODIUM CITRATE (UNII: 1Q73Q2JULR)  
    SORBITOL (UNII: 506T60A25R)  
    SUCRALOSE (UNII: 96K6UQ3ZD4)  
    XANTHAN GUM (UNII: TTV12P4NEE)  
    Product Characteristics
    ColorBLUEScore    
    ShapeSize
    FlavorBERRY (Mixed Berry) Imprint Code
    Contains    
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:49035-623-031 in 1 CARTON08/01/2017
    1118 mL in 1 BOTTLE; Type 0: Not a Combination Product
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    OTC MONOGRAPH FINALpart34108/01/2017
    Labeler - Wal-Mart Stores, Inc. (051957769)
    Establishment
    NameAddressID/FEIBusiness Operations
    Guardian Drug Company119210276MANUFACTURE(49035-623)