Label: SPOTLESS DAILY ACNE WASH- benzoyl peroxide cream

  • Category: HUMAN OTC DRUG LABEL
  • DEA Schedule: None

Drug Label Information

Updated February 4, 2026

If you are a consumer or patient please visit this version.

View All Sections
  • Active ingredient

    Benzoyl peroxide 5%

  • Purpose

    Acne treatment

  • Uses

    • for the treatment of acne
    • helps keep skin clear of new acne blemishes, acne pimples, blackheads and whiteheads
  • Warnings

    For external use only

    Do not use if you

    • have very sensitive skin
    • are sensitive to benzoyl peroxide

    When using this product

    • skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration.
    • skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
    • avoid unnecessary sun exposure and use a sunscreen
    • avoid contact with the eyes, lips and mouth
    • avoid contact with hair and dyed fabrics, which may be bleached by this product

    Stop use and ask a doctor if

    • irritation becomes severe

    Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

  • Directions

    • wet skin with lukewarm water
    • using fingertips, apply a thin, even layer and massage over entire face for 90 seconds, avoiding all contact with eyes
    • rinse thoroughly and pat dry
    • use once daily and increase to twice daily as tolerated
    • wash hands after application to help avoid staining fabrics
    • because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor
    • if bothersome dryness or peeling occurs, reduce application to once a day or every other day
    • if going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor.
  • Other information

    store between 15-30°C (59-86°F)

  • Inactive ingredients

    water, polyacrylamide, C13-14 isoalkane, jojoba esters, carbomer, diethylhexyl sodium sulfosuccinate, cocamidopropyl betaine, laureth-7, sodium chloride, sodium citrate, sodium hydroxide, propanediol, ethylhexylglycerin, phenoxyethanol, sodium benzoate

  • Questions?

    1-888-995-5656

  • Principal Display Panel - 125 mL Carton Label

    RODAN+FIELDS
    SPOTLESS

    DAILY
    ACNE
    WASH

    1

    125 mL/4.2 Fl. Oz. U.S.

    Principal Display Panel - 125 mL Carton Label
  • Principal Display Panel - 125 mL Tube Label

    RODAN+FIELDS
    SPOTLESS

    DAILY
    ACNE
    WASH

    1

    Principal Display Panel - 125 mL Tube Label
  • INGREDIENTS AND APPEARANCE
    SPOTLESS DAILY ACNE WASH 
    benzoyl peroxide cream
    Product Information
    Product TypeHUMAN OTC DRUGItem Code (Source)NDC:14222-1610
    Route of AdministrationTOPICAL
    Active Ingredient/Active Moiety
    Ingredient NameBasis of StrengthStrength
    BENZOYL PEROXIDE (UNII: W9WZN9A0GM) (BENZOYL PEROXIDE - UNII:W9WZN9A0GM) BENZOYL PEROXIDE0.05 g  in 1 mL
    Inactive Ingredients
    Ingredient NameStrength
    WATER (UNII: 059QF0KO0R)  
    POLYACRYLAMIDE (10000 MW) (UNII: E2KR9C9V2I)  
    C13-14 ISOPARAFFIN (UNII: E4F12ROE70)  
    CARBOXYPOLYMETHYLENE (UNII: 0A5MM307FC)  
    COCAMIDOPROPYL BETAINE (UNII: 5OCF3O11KX)  
    DOCUSATE SODIUM (UNII: F05Q2T2JA0)  
    ETHYLHEXYLGLYCERIN (UNII: 147D247K3P)  
    HYDROGENATED JOJOBA OIL, RANDOMIZED (UNII: Q47ST02F58)  
    LAURETH-7 (UNII: Z95S6G8201)  
    PHENOXYETHANOL (UNII: HIE492ZZ3T)  
    PROPANEDIOL (UNII: 5965N8W85T)  
    SODIUM BENZOATE (UNII: OJ245FE5EU)  
    SODIUM CHLORIDE (UNII: 451W47IQ8X)  
    SODIUM CITRATE, UNSPECIFIED FORM (UNII: 1Q73Q2JULR)  
    SODIUM HYDROXIDE (UNII: 55X04QC32I)  
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:14222-1610-11 in 1 CARTON02/13/2019
    1125 mL in 1 TUBE; Type 0: Not a Combination Product
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    OTC Monograph DrugM00602/13/2019
    Labeler - Rodan & Fields (051659584)
View All Sections

Find additional resources

(also available in the left menu)

Safety

Report Adverse Events, FDA Safety Recalls, Presence in Breast Milk

Related Resources

Medline Plus, Clinical Trials, PubMed, Biochemical Data Summary

More Info on this Drug

View Labeling Archives, RxNorm, Get Label RSS Feed, View NDC Code(s)NEW!