Label: SPOTLESS REGIMEN FOR ACNE, BLEMISHES AND BREAKOUTS- benzoyl peroxide kit
SPOTLESS 30-DAY REGIMEN- benzoyl peroxide kit

  • NDC Code(s): 14222-1600-1, 14222-1602-1, 14222-1610-2, 14222-1610-3, view more
    14222-1620-2, 14222-1620-3
  • Packager: Rodan & Fields
  • Category: HUMAN OTC DRUG LABEL
  • DEA Schedule: None

Drug Label Information

Updated February 4, 2026

If you are a consumer or patient please visit this version.

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  • SPL UNCLASSIFIED SECTION

    DAILY ACNE WASH

    Drug Facts

  • Active ingredient

    Benzoyl peroxide 5%

  • Purpose

    Acne treatment

  • Uses

    • for the treatment of acne
    • helps keep skin clear of new acne blemishes, acne pimples, blackheads and whiteheads
  • Warnings

    For external use only

    Do not use if you

    • have very sensitive skin
    • are sensitive to benzoyl peroxide

    When using this product

    • skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration.
    • skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
    • avoid unnecessary sun exposure and use a sunscreen
    • avoid contact with the eyes, lips and mouth
    • avoid contact with hair and dyed fabrics, which may be bleached by this product

    Stop use and ask a doctor if

    • irritation becomes severe

    Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

  • Directions

    • wet skin with lukewarm water
    • using fingertips, apply a thin, even layer and massage over entire face for 90 seconds, avoiding all contact with eyes
    • rinse thoroughly and pat dry
    • use once daily and increase to twice daily as tolerated
    • wash hands after application to help avoid staining fabrics
    • because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor
    • if bothersome dryness or peeling occurs, reduce application to once a day or every other day
    • if going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor.
  • Other information

    store between 15-30°C (59-86°F)

  • Inactive ingredients

    water, polyacrylamide, C13-14 isoalkane, jojoba esters, carbomer, diethylhexyl sodium sulfosuccinate, cocamidopropyl betaine, laureth-7, sodium chloride, sodium citrate, sodium hydroxide, propanediol, ethylhexylglycerin, phenoxyethanol, sodium benzoate

  • Questions?

    1-888-995-5656

  • SPL UNCLASSIFIED SECTION

    ACNE CLEARING TREATMENT

    Drug Facts

  • Active ingredient

    Benzoyl peroxide 2.5%

  • Purpose

    Acne treatment

  • Uses

    • for the treatment of acne
    • helps keep skin clear of new acne blemishes, acne pimples, blackheads and whiteheads
  • Warnings

    For external use only

    Do not use if you

    • have very sensitive skin
    • are sensitive to benzoyl peroxide

    When using this product

    • skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration.
    • skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
    • avoid unnecessary sun exposure and use a sunscreen
    • avoid contact with the eyes, lips and mouth
    • avoid contact with hair and dyed fabrics, which may be bleached by this product

    Stop use and ask a doctor if

    • irritation becomes severe

    Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

  • Directions

    • clean the skin thoroughly before applying this product
    • dispense 1-2 pumps and cover the entire affected area with a thin, even layer one to three times daily
    • do not rinse product off face
    • wash hands after application to help avoid staining fabrics
    • because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor
    • if bothersome dryness or peeling occurs, reduce application to once a day or every other day
    • if going outside, apply sunscreen after using this product.

    If irritation or sensitivity develops, stop use of both products and ask a doctor.

  • Other information

    store between 15-30°C (59-86°F)

  • Inactive ingredients

    water/aqua/eau, glycereth-18 ethylhexanoate, glycereth-18, disiloxane, glycerin, butylene glycol, propanediol, acrylamide/sodium acryloyldimethyltaurate copolymer, allantoin, ascorbyl palmitate, bisabolol, myristyl alcohol, PCA, phytosteryl/octyldodecyl lauroyl glutamate, polygonum cuspidatum root extract, sodium hyaluronate, zingiber officinale (ginger) root extract, fragrance/parfum, carbomer, methyl methacrylate crosspolymer, cetyl hydroxyethylcellulose, hydroxyphenyl propamidobenzoic acid, polyglyceryl-2 isostearate, polysorbate 80, sorbitan oleate, xanthan gum, diethylhexyl sodium sulfosuccinate, isohexadecane, dimethyl isosorbide, tocopherol, citric acid, sodium citrate, sodium hydroxide, caprylyl glycol, decylene glycol, hexylene glycol, pentylene glycol, 1,2-hexanediol, ethylhexylglycerin, hydroxyacetophenone, phenoxyethanol, citral, citronellol, limonene, linalool, carvone, citrus aurantium peel oil, mentha viridis (spearmint) leaf oil, pinene, mica, tin oxide, titanium dioxide (CI 77891), blue 1 (CI 42090), ext. violet 2 (CI 60730), red 33 (CI 17200)

  • Questions?

    1-888-995-5656

  • Principal Display Panel - Kit Label

    RODAN+FIELDS

    SPOTLESS

    REGIMEN FOR
    ACNE, BLEMISHES
    AND BREAKOUTS

    DESIGNED FOR
    TEENS AND YOUNG ADULTS

    • Eliminates acne-causing bacteria
    • Helps clear blackheads, whiteheads
      and pimples
    • Helps prevent new blemishes
      from forming
    • Reduces shine

    DEVELOPED BY STANFORD-TRAINED
    DERMATOLOGISTS DR.KATIE RODAN
    AND DR.KATHY FIELDS

    Daily Acne Wash

    Benzoyl Peroxide Cream

    125 mL/4.2 Fl. Oz. U.S.

    Acne Clearing Treatment

    Benzoyl Peroxide Lotion*

    50 mL/1.7 Fl. Oz. U.S.

    Figure
  • Principal Display Panel - Daily Acne Wash Tube Label

    RODAN+FIELDS
    SPOTLESS

    DAILY
    ACNE
    WASH

    1

    Figure
  • Principal Display Panel - Acne Clearing Treatment Tube Label

    RODAN+FIELDS
    SPOTLESS

    ACNE
    CLEARING
    TREATMENT

    2

    Figure
  • Principal Display Panel - 30-DAY KIT Carton Label

    RODAN+FIELDS

    SPOTLESS
    30-DAY REGIMEN
    FOR TEEN ACNE

    FEMALE FOUNDED + DERMATOLOGIST DEVELOPED

    95%
    HAD LESS
    ACNE IN
    5 DAYS**

    DAILY ACNE WASH
    BENZOYL PEROXIDE
    CREAM WASH
    65 ML / 2.2 FL. OZ.

    ACNE CLEARING
    TREATMENT
    BENZOYL PEROXIDE
    CREAM LOTION***

    2 x 10 ML / 2 x 0.33 FL. OZ.

    Figure
  • Principal Display Panel - 65 mL Tube Label

    RODAN+FIELDS
    SPOTLESS

    DAILY
    ACNE
    WASH
    1

    Benzoyl Peroxide Cream Wash

    Figure
  • Principal Display Panel - 20 mL Tube Label

    RODAN+FIELDS
    SPOTLESS

    ACNE
    CLEARING
    TREATMENT
    2

    Benzoyl Peroxide Lotion

    Figure
  • INGREDIENTS AND APPEARANCE
    SPOTLESS REGIMEN FOR ACNE, BLEMISHES AND BREAKOUTS 
    benzoyl peroxide kit
    Product Information
    Product TypeHUMAN OTC DRUGItem Code (Source)NDC:14222-1600
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:14222-1600-11 in 1 CARTON; Type 1: Convenience Kit of Co-Package02/13/2019
    Quantity of Parts
    Part #Package QuantityTotal Product Quantity
    Part 11 TUBE 125 mL
    Part 21 BOTTLE, PUMP 50 mL
    Part 1 of 2
    SPOTLESS DAILY ACNE WASH 
    benzoyl peroxide cream
    Product Information
    Item Code (Source)NDC:14222-1610
    Route of AdministrationTOPICAL
    Active Ingredient/Active Moiety
    Ingredient NameBasis of StrengthStrength
    BENZOYL PEROXIDE (UNII: W9WZN9A0GM) (BENZOYL PEROXIDE - UNII:W9WZN9A0GM) BENZOYL PEROXIDE0.05 g  in 1 mL
    Inactive Ingredients
    Ingredient NameStrength
    WATER (UNII: 059QF0KO0R)  
    POLYACRYLAMIDE (10000 MW) (UNII: E2KR9C9V2I)  
    C13-14 ISOPARAFFIN (UNII: E4F12ROE70)  
    CARBOXYPOLYMETHYLENE (UNII: 0A5MM307FC)  
    COCAMIDOPROPYL BETAINE (UNII: 5OCF3O11KX)  
    DOCUSATE SODIUM (UNII: F05Q2T2JA0)  
    ETHYLHEXYLGLYCERIN (UNII: 147D247K3P)  
    HYDROGENATED JOJOBA OIL, RANDOMIZED (UNII: Q47ST02F58)  
    LAURETH-7 (UNII: Z95S6G8201)  
    PHENOXYETHANOL (UNII: HIE492ZZ3T)  
    PROPANEDIOL (UNII: 5965N8W85T)  
    SODIUM BENZOATE (UNII: OJ245FE5EU)  
    SODIUM CHLORIDE (UNII: 451W47IQ8X)  
    SODIUM CITRATE, UNSPECIFIED FORM (UNII: 1Q73Q2JULR)  
    SODIUM HYDROXIDE (UNII: 55X04QC32I)  
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:14222-1610-2125 mL in 1 TUBE; Type 1: Convenience Kit of Co-Package
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    OTC Monograph DrugM00602/13/2019
    Part 2 of 2
    SPOTLESS ACNE CLEARING TREATMENT 
    benzoyl peroxide lotion
    Product Information
    Item Code (Source)NDC:14222-1620
    Route of AdministrationTOPICAL
    Active Ingredient/Active Moiety
    Ingredient NameBasis of StrengthStrength
    BENZOYL PEROXIDE (UNII: W9WZN9A0GM) (BENZOYL PEROXIDE - UNII:W9WZN9A0GM) BENZOYL PEROXIDE0.025 g  in 1 mL
    Inactive Ingredients
    Ingredient NameStrength
    WATER (UNII: 059QF0KO0R)  
    GLYCERETH-18 ETHYLHEXANOATE (UNII: IWS58C6V2Y)  
    GLYCERETH-18 (UNII: SA5E43C17C)  
    HEXAMETHYLDISILOXANE (UNII: D7M4659BPU)  
    GLYCERIN (UNII: PDC6A3C0OX)  
    BUTYLENE GLYCOL (UNII: 3XUS85K0RA)  
    PROPANEDIOL (UNII: 5965N8W85T)  
    ACRYLAMIDE/SODIUM ACRYLOYLDIMETHYLTAURATE COPOLYMER (120000 MPA.S AT 1%) (UNII: 5F4963KLHS)  
    ALLANTOIN (UNII: 344S277G0Z)  
    ASCORBYL PALMITATE (UNII: QN83US2B0N)  
    LEVOMENOL (UNII: 24WE03BX2T)  
    MYRISTYL ALCOHOL (UNII: V42034O9PU)  
    PIDOLIC ACID (UNII: SZB83O1W42)  
    PHYTOSTERYL/OCTYLDODECYL LAUROYL GLUTAMATE (UNII: 65954KGO9Q)  
    REYNOUTRIA JAPONICA ROOT (UNII: 7TRV45YZF7)  
    HYALURONATE SODIUM (UNII: YSE9PPT4TH)  
    GINGER (UNII: C5529G5JPQ)  
    POLYACRYLIC ACID (800000 MW) (UNII: D0I6NSZ87U)  
    METHYL METHACRYLATE/GLYCOL DIMETHACRYLATE CROSSPOLYMER (UNII: EG97988M5Q)  
    CETYL HYDROXYETHYLCELLULOSE (350000 MW) (UNII: T7SWE4S2TT)  
    HYDROXYPHENYL PROPAMIDOBENZOIC ACID (UNII: 25KRT26H77)  
    POLYGLYCERYL-2 ISOSTEARATE (UNII: 7B8OE71MQC)  
    POLYSORBATE 80 (UNII: 6OZP39ZG8H)  
    SORBITAN MONOOLEATE (UNII: 06XEA2VD56)  
    XANTHAN GUM (UNII: TTV12P4NEE)  
    DOCUSATE SODIUM (UNII: F05Q2T2JA0)  
    ISOHEXADECANE (UNII: 918X1OUF1E)  
    DIMETHYL ISOSORBIDE (UNII: SA6A6V432S)  
    TOCOPHEROL (UNII: R0ZB2556P8)  
    CITRIC ACID MONOHYDRATE (UNII: 2968PHW8QP)  
    SODIUM CITRATE, UNSPECIFIED FORM (UNII: 1Q73Q2JULR)  
    SODIUM HYDROXIDE (UNII: 55X04QC32I)  
    CAPRYLYL GLYCOL (UNII: 00YIU5438U)  
    DECYLENE GLYCOL (UNII: S57M60MI88)  
    HEXYLENE GLYCOL (UNII: KEH0A3F75J)  
    PENTYLENE GLYCOL (UNII: 50C1307PZG)  
    1,2-HEXANEDIOL (UNII: TR046Y3K1G)  
    ETHYLHEXYLGLYCERIN (UNII: 147D247K3P)  
    HYDROXYACETOPHENONE (UNII: G1L3HT4CMH)  
    PHENOXYETHANOL (UNII: HIE492ZZ3T)  
    CITRAL (UNII: T7EU0O9VPP)  
    .BETA.-CITRONELLOL, (R)- (UNII: P01OUT964K)  
    LIMONENE, (+/-)- (UNII: 9MC3I34447)  
    LINALOOL, (+/-)- (UNII: D81QY6I88E)  
    CARVONE, (+/-)- (UNII: 75GK9XIA8I)  
    BITTER ORANGE OIL (UNII: 9TLV70SV6I)  
    SPEARMINT OIL (UNII: C3M81465G5)  
    PINENE (UNII: 996299PUKB)  
    MICA (UNII: V8A1AW0880)  
    STANNIC OXIDE (UNII: KM7N50LOS6)  
    TITANIUM DIOXIDE (UNII: 15FIX9V2JP)  
    FD&C BLUE NO. 1 (UNII: H3R47K3TBD)  
    Ext. D&C VIOLET NO. 2 (UNII: G5UX3K0728)  
    D&C RED NO. 33 (UNII: 9DBA0SBB0L)  
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:14222-1620-250 mL in 1 BOTTLE, PUMP; Type 1: Convenience Kit of Co-Package
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    OTC Monograph DrugM00602/13/2019
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    OTC Monograph DrugM00602/13/2019
    SPOTLESS 30-DAY REGIMEN 
    benzoyl peroxide kit
    Product Information
    Product TypeHUMAN OTC DRUGItem Code (Source)NDC:14222-1602
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:14222-1602-11 in 1 CARTON; Type 1: Convenience Kit of Co-Package01/24/2025
    Quantity of Parts
    Part #Package QuantityTotal Product Quantity
    Part 11 TUBE 65 mL
    Part 21 BOTTLE, PUMP 20 mL
    Part 1 of 2
    SPOTLESS DAILY ACNE WASH 
    benzoyl peroxide cream
    Product Information
    Item Code (Source)NDC:14222-1610
    Route of AdministrationTOPICAL
    Active Ingredient/Active Moiety
    Ingredient NameBasis of StrengthStrength
    BENZOYL PEROXIDE (UNII: W9WZN9A0GM) (BENZOYL PEROXIDE - UNII:W9WZN9A0GM) BENZOYL PEROXIDE0.05 g  in 1 mL
    Inactive Ingredients
    Ingredient NameStrength
    WATER (UNII: 059QF0KO0R)  
    POLYACRYLAMIDE (10000 MW) (UNII: E2KR9C9V2I)  
    C13-14 ISOPARAFFIN (UNII: E4F12ROE70)  
    CARBOXYPOLYMETHYLENE (UNII: 0A5MM307FC)  
    COCAMIDOPROPYL BETAINE (UNII: 5OCF3O11KX)  
    DOCUSATE SODIUM (UNII: F05Q2T2JA0)  
    ETHYLHEXYLGLYCERIN (UNII: 147D247K3P)  
    HYDROGENATED JOJOBA OIL, RANDOMIZED (UNII: Q47ST02F58)  
    LAURETH-7 (UNII: Z95S6G8201)  
    PHENOXYETHANOL (UNII: HIE492ZZ3T)  
    PROPANEDIOL (UNII: 5965N8W85T)  
    SODIUM BENZOATE (UNII: OJ245FE5EU)  
    SODIUM CHLORIDE (UNII: 451W47IQ8X)  
    SODIUM CITRATE, UNSPECIFIED FORM (UNII: 1Q73Q2JULR)  
    SODIUM HYDROXIDE (UNII: 55X04QC32I)  
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:14222-1610-365 mL in 1 TUBE; Type 1: Convenience Kit of Co-Package
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    OTC Monograph DrugM00601/24/2025
    Part 2 of 2
    SPOTLESS ACNE CLEARING TREATMENT 
    benzoyl peroxide lotion
    Product Information
    Item Code (Source)NDC:14222-1620
    Route of AdministrationTOPICAL
    Active Ingredient/Active Moiety
    Ingredient NameBasis of StrengthStrength
    BENZOYL PEROXIDE (UNII: W9WZN9A0GM) (BENZOYL PEROXIDE - UNII:W9WZN9A0GM) BENZOYL PEROXIDE0.025 g  in 1 mL
    Inactive Ingredients
    Ingredient NameStrength
    WATER (UNII: 059QF0KO0R)  
    GLYCERETH-18 ETHYLHEXANOATE (UNII: IWS58C6V2Y)  
    GLYCERETH-18 (UNII: SA5E43C17C)  
    HEXAMETHYLDISILOXANE (UNII: D7M4659BPU)  
    GLYCERIN (UNII: PDC6A3C0OX)  
    BUTYLENE GLYCOL (UNII: 3XUS85K0RA)  
    PROPANEDIOL (UNII: 5965N8W85T)  
    ACRYLAMIDE/SODIUM ACRYLOYLDIMETHYLTAURATE COPOLYMER (120000 MPA.S AT 1%) (UNII: 5F4963KLHS)  
    ALLANTOIN (UNII: 344S277G0Z)  
    ASCORBYL PALMITATE (UNII: QN83US2B0N)  
    LEVOMENOL (UNII: 24WE03BX2T)  
    MYRISTYL ALCOHOL (UNII: V42034O9PU)  
    PIDOLIC ACID (UNII: SZB83O1W42)  
    PHYTOSTERYL/OCTYLDODECYL LAUROYL GLUTAMATE (UNII: 65954KGO9Q)  
    REYNOUTRIA JAPONICA ROOT (UNII: 7TRV45YZF7)  
    HYALURONATE SODIUM (UNII: YSE9PPT4TH)  
    GINGER (UNII: C5529G5JPQ)  
    POLYACRYLIC ACID (800000 MW) (UNII: D0I6NSZ87U)  
    METHYL METHACRYLATE/GLYCOL DIMETHACRYLATE CROSSPOLYMER (UNII: EG97988M5Q)  
    CETYL HYDROXYETHYLCELLULOSE (350000 MW) (UNII: T7SWE4S2TT)  
    HYDROXYPHENYL PROPAMIDOBENZOIC ACID (UNII: 25KRT26H77)  
    POLYGLYCERYL-2 ISOSTEARATE (UNII: 7B8OE71MQC)  
    POLYSORBATE 80 (UNII: 6OZP39ZG8H)  
    SORBITAN MONOOLEATE (UNII: 06XEA2VD56)  
    XANTHAN GUM (UNII: TTV12P4NEE)  
    DOCUSATE SODIUM (UNII: F05Q2T2JA0)  
    ISOHEXADECANE (UNII: 918X1OUF1E)  
    DIMETHYL ISOSORBIDE (UNII: SA6A6V432S)  
    TOCOPHEROL (UNII: R0ZB2556P8)  
    CITRIC ACID MONOHYDRATE (UNII: 2968PHW8QP)  
    SODIUM CITRATE, UNSPECIFIED FORM (UNII: 1Q73Q2JULR)  
    SODIUM HYDROXIDE (UNII: 55X04QC32I)  
    CAPRYLYL GLYCOL (UNII: 00YIU5438U)  
    DECYLENE GLYCOL (UNII: S57M60MI88)  
    HEXYLENE GLYCOL (UNII: KEH0A3F75J)  
    PENTYLENE GLYCOL (UNII: 50C1307PZG)  
    1,2-HEXANEDIOL (UNII: TR046Y3K1G)  
    ETHYLHEXYLGLYCERIN (UNII: 147D247K3P)  
    HYDROXYACETOPHENONE (UNII: G1L3HT4CMH)  
    PHENOXYETHANOL (UNII: HIE492ZZ3T)  
    CITRAL (UNII: T7EU0O9VPP)  
    .BETA.-CITRONELLOL, (R)- (UNII: P01OUT964K)  
    LIMONENE, (+/-)- (UNII: 9MC3I34447)  
    LINALOOL, (+/-)- (UNII: D81QY6I88E)  
    CARVONE, (+/-)- (UNII: 75GK9XIA8I)  
    BITTER ORANGE OIL (UNII: 9TLV70SV6I)  
    SPEARMINT OIL (UNII: C3M81465G5)  
    PINENE (UNII: 996299PUKB)  
    MICA (UNII: V8A1AW0880)  
    STANNIC OXIDE (UNII: KM7N50LOS6)  
    TITANIUM DIOXIDE (UNII: 15FIX9V2JP)  
    FD&C BLUE NO. 1 (UNII: H3R47K3TBD)  
    Ext. D&C VIOLET NO. 2 (UNII: G5UX3K0728)  
    D&C RED NO. 33 (UNII: 9DBA0SBB0L)  
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:14222-1620-320 mL in 1 BOTTLE, PUMP; Type 1: Convenience Kit of Co-Package
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    OTC Monograph DrugM00601/24/2025
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    OTC Monograph DrugM00601/24/2025
    Labeler - Rodan & Fields (051659584)
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