Label: UP AND UP NIGHTTIME SLEEP AID- diphenhydramine hydrochloride solution

  • Category: HUMAN OTC DRUG LABEL
  • DEA Schedule: None
  • Marketing Status: OTC monograph final

DISCLAIMER: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

Drug Label Information

Updated February 23, 2023

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  • Active ingredient (in each 30 mL)

    Diphenhydramine HCl 50 mg

  • Purpose

    Nighttime sleep-aid

  • Uses

    ▪
    for the relief of occasional sleeplessness
    ▪
    reduces time to fall asleep if you have difficulty falling asleep
  • Warnings

    Do not use

    ▪
    for children under 12 years of age
    ▪
    with any other product containing diphenhydramine, even one used on skin

    Ask a doctor before use if you have

    ▪
    a breathing problem such as emphysema or chronic bronchitis
    ▪
    glaucoma
    ▪
    difficulty in urination dur to enlargement of the prostate gland

    Ask a doctor or pharmacist before use if you are

    taking sedative or tranquilizers

    When using this product

    ▪
    avoid alcoholic beverages

    Stop use and ask a doctor if

    sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness.

    If pregnant or breast-feeding,

    ask a health professional before use

    Keep out of reach of children.

    In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

  • Directions

    ▪
    take only one does per day (24 hours)
    ▪
    only use the dose cup provided
     
    adults & children 12 yrs & over
     
    30 mL at bed time if needed or as directed by a doctor
     
    children under 12 yrs
     
    do not use
  • Other information

    ▪
    each 30 mL contains: sodium 20 mg
    ▪
    store at 20-25°C (68-77°F)
  • Inactive ingredients

    alcohol, anhydrous citric acid, FD&C blue #1, FD&C red #40, flavor, high fructose corn syrup, poloxamer 407, propylene glycol, purified water, saccharin sodium, sodium benzoate, sodium citrate

  • Questions?

    1-888-547-7400

  • Package/Label Principal Display Panel

    Compare to active ingredient in Vicks® ZzzQuil®

    nighttime sleep aid

    diphenhydramine HCl 50 mg per 30 mL

    non habit-forming

    not for treating cold or flu

    ALCOHOL 10%

    up & up ™

    BERRY FLAVOR

    12 FL OZ (355 mL)

    nighttime sleep aid-image
  • INGREDIENTS AND APPEARANCE
    UP AND UP NIGHTTIME SLEEP AID 
    diphenhydramine hydrochloride solution
    Product Information
    Product TypeHUMAN OTC DRUGItem Code (Source)NDC:11673-186
    Route of AdministrationORAL
    Active Ingredient/Active Moiety
    Ingredient NameBasis of StrengthStrength
    DIPHENHYDRAMINE HYDROCHLORIDE (UNII: TC2D6JAD40) (DIPHENHYDRAMINE - UNII:8GTS82S83M) DIPHENHYDRAMINE HYDROCHLORIDE50 mg  in 30 mL
    Inactive Ingredients
    Ingredient NameStrength
    ALCOHOL (UNII: 3K9958V90M)  
    ANHYDROUS CITRIC ACID (UNII: XF417D3PSL)  
    FD&C BLUE NO. 1 (UNII: H3R47K3TBD)  
    FD&C RED NO. 40 (UNII: WZB9127XOA)  
    HIGH FRUCTOSE CORN SYRUP (UNII: XY6UN3QB6S)  
    POLOXAMER 407 (UNII: TUF2IVW3M2)  
    PROPYLENE GLYCOL (UNII: 6DC9Q167V3)  
    WATER (UNII: 059QF0KO0R)  
    SACCHARIN SODIUM (UNII: SB8ZUX40TY)  
    SODIUM BENZOATE (UNII: OJ245FE5EU)  
    SODIUM CITRATE, UNSPECIFIED FORM (UNII: 1Q73Q2JULR)  
    Product Characteristics
    ColorPURPLEScore    
    ShapeSize
    FlavorBERRYImprint Code
    Contains    
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:11673-186-40355 mL in 1 BOTTLE; Type 0: Not a Combination Product03/26/2020
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    OTC monograph finalpart33803/26/2020
    Labeler - Target Corporation (006961700)
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