PHENYTOIN- phenytoin suspension 
PAI Holdings, LLC


Phenytoin (fen' i toin) Oral Suspension, USP

What is the most important information I should know about phenytoin oral suspension?

  • Thoughts about suicide or dying
  • Attempts to commit suicide
  • New or worse depression
  • New or worse anxiety
  • Feeling agitated or restless
  • Panic attacks
  • Trouble sleeping (insomnia)
  • New or worse irritability
  • Acting aggressive, being angry, or violent
  • Acting on dangerous impulses
  • An extreme increase in activity and talking (mania)
  • Other unusual changes in behavior or mood

Suicidal thoughts or actions can be caused by things other than medicines. If you have suicidal thoughts or actions, your healthcare provider may check for other causes.

How can I watch for early symptoms of suicidal thoughts and actions?

Call your healthcare provider between visits as needed, especially if you are worried about symptoms.

  • Fever
  • Rash
  • Swollen lymph glands
  • Swelling of your face, eye, lips, or tongue
  • Trouble swallowing or breathing
  • Sore throat
  • Sores in your mouth
  • Bruise easily
  • Purple or red spots on your skin
  • Increase infections
  • Not wanting to eat (anorexia)
  • Nausea
  • Vomiting
  • Yellowing of the skin and the white part of your eyes (jaundice)

Call your healthcare provider even if the symptoms are mild or if you have been taking phenytoin for an extended period of time. These symptoms can be a sign of a serious allergic reaction.

  • dizziness
  • feeling like your heart is beating slowly or skipping beats
  • tiredness
  • chest pain

What is phenytoin oral suspension?

Phenytoin oral suspension is a prescription medicine used to treat certain types of seizures called tonic-clonic (grand mal) and psychomotor (temporal lobe) seizures.

Do not take phenytoin oral suspension if you:

Before taking phenytoin oral suspension, tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. These medicines can change the levels of phenytoin in your blood.

Taking phenytoin oral suspension with certain other medicines can cause side effects or affect how well they work. Do not start or stop other medicines without talking to your healthcare provider. Know the medicines you take. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new medicine.

How should I take phenytoin oral suspension?

What should I avoid while taking phenytoin oral suspension?

What are the possible side effects of phenytoin oral suspension?

See " What is the most important information I should know about phenytoin oral suspension?"

Phenytoin oral suspension may cause other serious side effects including:

Call your healthcare provider right away, if you have any of the symptoms listed above. The most common side effects of phenytoin oral suspension include:

  • Irregular movement of the eye (nystagmus)
  • Problems with movement and balance (ataxia)
  • Slurred speech
  • Decrease in coordination
  • Drowsiness (somnolence)
  • Confusion

Phenytoin can cause overgrowth of your gums. Brushing and flossing your teeth and seeing a dentist regularly while taking phenytoin oral suspension can help prevent this from happening.

These are not all of the possible side effects of phenytoin oral suspension.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store phenytoin oral suspension?

Keep phenytoin oral suspension and all medicines out of the reach of children.

General information about the safe and effective use of phenytoin oral suspension.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use phenytoin oral suspension for a condition for which it was not prescribed. Do not give phenytoin oral suspension to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about phenytoin oral suspension that is written for health professionals.

What are the ingredients in phenytoin oral suspension?

Active ingredient: phenytoin, USP

Inactive ingredients: carboxymethylcellulose sodium, citric acid anhydrous, FD&C yellow no. 6, magnesium aluminum silicate, orange flavor spray dry natural and artificial, polysorbate 60, purified water, sodium benzoate, sucrose and vanilla flavored powder artificial.


Associates, Inc.

Greenville, SC 29605

This Medication Guide has been approved by the U.S. Food and Drug Administration

Revised: April 2020

Revised: 11/2022
PAI Holdings, LLC