EPZICOM- abacavir sulfate and lamivudine tablet, film coated
ViiV Healthcare Company
EPZICOM® (ep' zih com)
(abacavir and lamivudine)
What is the most important information I should know about EPZICOM?
EPZICOM can cause serious side effects, including:
Group 1 Fever
Group 2 Rash
Group 3 Nausea, vomiting, diarrhea, abdominal (stomach area) pain
Group 4 Generally ill feeling, extreme tiredness, or achiness
Group 5 Shortness of breath, cough, sore throat
If your healthcare provider tells you that you can take EPZICOM again, start taking it when you are around medical help or people who can call a healthcare provider if you need one.
• feel very weak or tired • feel cold, especially in your arms and legs
• unusual (not normal) muscle pain • feel dizzy or light-headed
• trouble breathing • have a fast or irregular heartbeat
• stomach pain with nausea and vomiting
• your skin or the white part of your eyes • loss of appetite for several days or longer
turns yellow (jaundice) • nausea
• dark or “tea-colored” urine • pain, aching, or tenderness on the right side
• light-colored stools (bowel movements) of your stomach area
You may be more likely to get lactic acidosis or serious liver problems if you are female, very overweight (obese), or have been taking nucleoside analogue medicines for a long time.
What is EPZICOM?
EPZICOM is a prescription HIV-1 (Human Immunodeficiency Virus-type 1) medicine used with other antiretroviral medicines to treat HIV-1 infection. HIV-1 is the virus that causes Acquired Immune Deficiency Syndrome (AIDS). EPZICOM contains 2 prescription medicines, abacavir (ZIAGEN) and lamivudine (EPIVIR®).
EPZICOM should not be used in children weighing less than 55 pounds (25 kg).
When used with other antiretroviral medicines to treat HIV-1 infection, EPZICOM may help:
Reducing the amount of HIV-1 and increasing the CD4+ (T) cells in your blood may help improve your immune system. This may reduce your risk of death or getting infections that can happen when your immune system is weak (opportunistic infections).
EPZICOM does not cure HIV-1 infection or AIDS. You must keep taking HIV-1 medicines to control HIV-1 infection and decrease HIV-related illnesses.
Who should not take EPZICOM?
Do not take EPZICOM if you:
What should I tell my healthcare provider before taking EPZICOM?
Before you take EPZICOM tell your healthcare provider if you:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Some medicines interact with EPZICOM. Keep a list of your medicines to show your healthcare provider and pharmacist. You can ask your healthcare provider or pharmacist for a list of medicines that interact with EPZICOM. Do not start taking a new medicine without telling your healthcare provider. Your healthcare provider can tell you if it is safe to take EPZICOM with other medicines.
Tell your healthcare provider if you take:
How should I take EPZICOM?
What are the possible side effects of EPZICOM?
The most common side effects of EPZICOM include:
Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of EPZICOM. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1‑800‑FDA‑1088.
How should I store EPZICOM?
Keep EPZICOM and all medicines out of the reach of children.
General information for safe and effective use of EPZICOM.
Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use EPZICOM for a condition for which it was not prescribed. Do not give EPZICOM to other people, even if they have the same symptoms that you have. It may harm them.
If you would like more information, talk with your healthcare provider. You can ask your healthcare provider or pharmacist for the information about EPZICOM that is written for health professionals.
For more information go to www.EPZICOM.com or call 1-877-844-8872.
What are the ingredients in EPZICOM?
Active ingredients: abacavir sulfate and lamivudine
Inactive ingredients: magnesium stearate, microcrystalline cellulose, sodium starch glycolate.
Tablet film coating contains: OPADRY® orange YS-1-13065-A made of FD&C Yellow No. 6, hypromellose, polyethylene glycol 400, polysorbate 80, and titanium dioxide.
Lamivudine is manufactured under agreement from Shire Pharmaceuticals Group plc, Basingstoke, UK
EPIVIR, EPZICOM, TRIUMEQ, TRIZIVIR, and ZIAGEN are registered trademarks of the ViiV Healthcare group of companies.
The other brands listed are trademarks of their respective owners and are not trademarks of the ViiV Healthcare group of companies. The makers of these brands are not affiliated with and do not endorse the ViiV Healthcare group of companies or its products.
©2017 the ViiV Healthcare group of companies. All rights reserved.
This Medication Guide has been approved by the U.S. Food and Drug Administration.