Medication Guide

Morphine Sulfate (mor’ feen sul’ fate) Suppositories, CII

Morphine Sulfate Suppositories are:

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A strong prescription pain medicine that contains an opioid (narcotic) that is used to manage short term (acute) and long term (chronic) pain severe enough to require an opioid pain medicine, when other pain treatments such as non-opioid pain medicines do not treat your pain well enough or you cannot tolerate them.

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An opioid pain medicine that can put you at risk for overdose and death. Even if you take your dose correctly as prescribed you are at risk for opioid addiction, abuse, and misuse that can lead to death.

Important information about morphine sulfate:

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Get emergency help right away if you take too many morphine sulfate suppositories (overdose). When you first start taking morphine sulfate suppositories, when your dose is changed, or if you take too much (overdose), serious or life-threatening breathing problems that can lead to death may occur.

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Taking morphine sulfate suppositories with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, decreased awareness, breathing problems, coma, and death.

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Never give anyone else your morphine sulfate suppositories. They could die from taking it. Store morphine sulfate suppositories away from children and in a safe place to prevent stealing or abuse. Selling or giving away morphine sulfate suppositories is against the law.

Do not take morphine sulfate suppositories if you have:

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severe asthma, trouble breathing, or other lung problems.

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a bowel blockage or have narrowing of the stomach or intestines.

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an allergy to morphine

Before taking morphine sulfate suppositories, tell your healthcare provider if you have a history of:

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head injury, seizures

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liver, kidney, thyroid problems

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problems urinating

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pancreas or gallbladder problems

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abuse of street or prescription drugs, alcohol addiction, or mental health problems.

Tell your healthcare provider if you are:

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pregnant or planning to become pregnant. Prolonged use of morphine sulfate suppositories during pregnancy can cause withdrawal symptoms in your newborn baby that could be life-threatening if not recognized and treated.

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breastfeeding. Morphine sulfate passes into breast milk and may harm your baby.

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taking prescription or over-the-counter medicines, vitamins, or herbal supplements. Taking morphine sulfate suppositories with certain other medicines can cause serious side effects that could lead to death.

When taking morphine sulfate suppositories:

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Do not change your dose. Take morphine sulfate suppositories exactly as prescribed by your healthcare provider. Use the lowest dose possible for the shortest time needed.

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Take your prescribed dose every 4 hours as needed for pain. Do not take more than your prescribed dose. If you miss a dose, take your next dose at your usual time.

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Call your healthcare provider if the dose you are taking does not control your pain.

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If you have been taking morphine sulfate suppositories regularly, do not stop taking morphine sulfate suppositories without talking to your healthcare provider.

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After you stop taking morphine sulfate suppositories, flush unused morphine sulfate suppositories down the toilet.

While taking morphine sulfate suppositories DO NOT:

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Drive or operate heavy machinery, until you know how morphine sulfate suppositories affects you. Morphine sulfate suppositories can make you sleepy, dizzy, or lightheaded.

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Drink alcohol or use prescription or over-the-counter medicines that contain alcohol. Using products containing alcohol during treatment with morphine sulfate suppositories may cause you to overdose and die.

The possible side effects of morphine sulfate suppositories:

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constipation, nausea, sleepiness, vomiting, tiredness, headache, dizziness, abdominal pain. Call your healthcare provider if you have any of these symptoms and they are severe.

Get emergency medical help if you have:

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trouble breathing, shortness of breath, fast heartbeat, chest pain, swelling of your face, tongue, or throat, extreme drowsiness, light-headedness when changing positions, feeling faint, agitation, high body temperature, trouble walking, stiff muscles, or mental changes such as confusion.

These are not all the possible side effects of morphine sulfate suppositories. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For more information go to dailymed.nlm.nih.gov.

Manufactured by: Perrigo, Minneapolis, MN 55427, www.perrigo.com or please call 1-866-634-9120

Issued: 11/2018

Manufactured By

Perrigo®

Minneapolis, MN 55427

www.perrigo.com

Rev 11-18 A

2203930

1R600 RC J1