IONSYS- fentanyl iontophoretic transdermal system patch 
The Medicines Company

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IONSYS ® Medication Guide

IONSYS ® (eye-AHN-sis)

(fentanyl iontophoretic transdermal system) CII

IONSYS is:

IONSYS device image

Important information about IONSYS:

Get emergency help right away if you use too much fentanyl, the active ingredient in IONSYS (overdose). Only you should press the button on IONSYS. When you first start using IONSYS, serious or life-threatening breathing problems that can lead to death may occur.

Do not use IONSYS if you have:

Before using IONSYS, tell your healthcare provider if you have a history of:

Tell your healthcare provider if you are:

Your healthcare provider:

How do I use IONSYS?

press and release dosing button image

Your healthcare provider will check your IONSYS to make sure it is working properly.

When using IONSYS:

Tell your healthcare provider right away if:

While using IONSYS DO NOT:

The possible side effects of IONSYS:

Tell your health care provider immediately if you have:

These are not all the possible side effects of IONSYS. Ask your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. For more information go to dailymed.nlm.nih.gov.

Manufactured, Distributed and Marketed by:

The Medicines Company

8 Sylvan Way

Parsippany, NJ 07054

December 2016

Part No. 308-0023 Rev 02

Software Version 205-0002, SB-SWC-002 Rev. 5, IT101 Controller Software, Version 1.6.715

Printed in USA

This Medication Guide has been approved by the U.S. Food and Drug Administration. Issued: 12/2016

Revised: 1/2017
The Medicines Company