MS CONTIN® (MS-KON-tin)
(morphine sulfate extended-release tablets), CII
MS CONTIN is:
- A strong prescription pain medicine that contains an opioid
(narcotic) that is used to manage pain severe enough to require daily
around-the-clock, long-term treatment with an opioid, when other pain
treatments such as non-opioid pain medicines or immediate-release
opioid medicines do not treat your pain well enough or you cannot
- A long-acting (extended-release) opioid pain medicine that
can put you at risk for overdose and death. Even if you take your
dose correctly as prescribed you are at risk for opioid addiction,
abuse, and misuse that can lead to death.
- Not for use to treat pain that is not around-the-clock.
Important information about MS CONTIN:
Get emergency help right away if you take too much
MS CONTIN (overdose). When you first start taking MS CONTIN,
when your dose is changed, or if you take too much (overdose), serious
or life-threatening breathing problems that can lead to death may
- Taking MS CONTIN with other opioid medicines, benzodiazepines,
alcohol, or other central nervous system depressants (including street
drugs) can cause severe drowsiness, decreased awareness, breathing
problems, coma, and death.
- Never give anyone else your MS CONTIN. They could die from
taking it. Store MS CONTIN away from children and in a safe place
to prevent stealing or abuse. Selling or giving away MS CONTIN is
against the law.
Do not take MS CONTIN if you have:
- severe asthma, trouble breathing, or other lung problems.
- a bowel blockage or have narrowing of the stomach or intestines.
Before taking MS CONTIN, tell your healthcare provider if
you have a history of:
- head injury, seizures
- liver, kidney, thyroid problems
- problems urinating
- pancreas or gallbladder problems
- abuse of street or prescription drugs, alcohol addiction,
or mental health problems.
Tell your healthcare provider if you are:
pregnant or planning to become pregnant. Prolonged
use of MS CONTIN during pregnancy can cause withdrawal symptoms in
your newborn baby that could be life-threatening if not recognized
breastfeeding. Not recommended during treatment
with MS CONTIN. It may harm your baby.
- taking prescription or over-the-counter medicines, vitamins,
or herbal supplements. Taking MS CONTIN with certain other medicines
can cause serious side effects.
When taking MS CONTIN:
- Do not change your dose. Take MS CONTIN exactly as prescribed
by your healthcare provider. Use the lowest dose possible for the
- Take your prescribed dose every 8 to 12 hours, as directed
by your healthcare provider. Do not take more than your prescribed
dose. If you miss a dose, take your next dose at the usual time.
- Swallow MS CONTIN whole. Do not cut, break, chew, crush,
dissolve, snort, or inject MS CONTIN because this may cause you to
overdose and die.
Call your healthcare provider if the dose you are
taking does not control your pain.
Do not stop taking MS CONTIN without talking to your
- After you stop taking MS CONTIN, flush any unused tablets
down the toilet.
While taking MS CONTIN DO NOT:
- Drive or operate heavy machinery, until you know how MS
CONTIN affects you. MS CONTIN can make you sleepy, dizzy, or lightheaded.
- Drink alcohol or use prescription or over-the-counter medicines
that contain alcohol. Using products containing alcohol during treatment
with MS CONTIN may cause you to overdose and die.
The possible side effects of MS CONTIN are:
- Constipation, nausea, sleepiness, vomiting, tiredness, headache,
dizziness, abdominal pain. Call your healthcare provider if you have
any of these symptoms and they are severe.
Get emergency medical help if you have:
These are not all the possible side effects of MS CONTIN.
Call your doctor for medical advice about side effects. You may report
side effects to FDA at 1-800-FDA-1088. For more information
go to dailymed.nlm.nih.gov
- trouble breathing, shortness of breath, fast heartbeat,
chest pain, swelling of your face, tongue or throat, extreme drowsiness,
light-headedness when changing positions, feeling faint, agitation,
high body temperature, trouble walking, stiff muscles, or mental changes
such as confusion.