NATPARA (PARATHYROID HORMONE)- parathyroid hormone injection, powder, lyophilized, for solution 
Shire-NPS Pharmaceuticals, Inc.

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Medication Guide

NATPARA® (nat-PAH-rah)
(parathyroid hormone)
for injection

What is the most important information I should know about NATPARA?

NATPARA may cause serious side effects, including:

Tell your doctor right away if you have any of these signs and symptoms of high or low blood calcium levels.

What is NATPARA?

It is not known if NATPARA is safe and effective for children 18 years of age and younger.

NATPARA should not be used in children and young adults whose bones are still growing.

Do not use NATPARA if you are allergic to parathyroid hormone or any of the ingredients in NATPARA. See the end of this Medication Guide for a complete list of ingredients in NATPARA.

Before you start using NATPARA, tell your doctor about all of your medical conditions, including if you:

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

NATPARA and other medicines may affect each other causing side effects.

Especially tell your doctor if you are taking medicines that contain digoxin, alendronate, calcium supplements or food products that contain calcium, or active vitamin D.

Know the medicines you take. Keep a list of them to show your doctor or pharmacist each time you get a new medicine.

How should I use NATPARA?

What are the possible side effects of NATPARA?

NATPARA may cause serious side effects, including:

  • swelling of your face, lips, mouth, or tongue
  • breathing problems
  • fainting, dizziness, feeling lightheaded (low blood pressure)
  • fast heartbeat
  • itching
  • rash
  • hives

Do not use NATPARA if you are allergic to parathyroid hormone or any of the ingredients in NATPARA. See the end of this Medication Guide for a complete list of ingredients in NATPARA.

The most common side effects of NATPARA include tingling, tickling, or a burning feeling of your skin (paresthesia), headache and nausea.

These are not all the possible side effects of NATPARA. For more information, ask your doctor. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store NATPARA?

Keep NATPARA and all medicines out of the reach of children.

General information about the safe and effective use of NATPARA.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use NATPARA for a condition for which it was not prescribed. Do not give NATPARA to other people, even if they have the same symptoms you have. It may harm them.

This Medication Guide summarizes the most important information about NATPARA. If you would like more information, talk with your doctor. You can ask your pharmacist or doctor for information about NATPARA that is written for health care professionals.

What are the ingredients in NATPARA?

Active ingredient: recombinant human parathyroid hormone

Inactive ingredients: sodium chloride, mannitol, citric acid monohydrate, m-cresol in sterile water

Manufactured for: Shire-NPS Pharmaceuticals, Inc., 300 Shire Way, Lexington, MA 02421, USA
U.S. License Number 1908

NATPARA® is a registered trademark of Shire-NPS Pharmaceuticals, Inc., a Takeda company.

Q-Cliq™ is a trademark of Shire-NPS Pharmaceuticals, Inc., a Takeda company.

©2020 Takeda Pharmaceutical Company Limited. All rights reserved.

For more information, go to www.NATPARA.com or call 1-800-828-2088.

This Medication Guide has been approved by the U.S. Food and Drug Administration.
Revised: 07/2020

Revised: 7/2020
Shire-NPS Pharmaceuticals, Inc.