Other symptoms may include:

• the acute (short-term) treatment of people 7 years of age and older with manic and mixed episodes that happen with bipolar I disorder.
• maintenance treatment of bipolar I disorder in people 7 years of age and older.

• have kidney problems

• have heart problems

• have breathing problems

• have thyroid problems

• are pregnant or plan to become pregnant. Lithium Oral Solution may harm your unborn baby.

• are breastfeeding or plan to breastfeed. Lithium can pass into your breastmilk and may harm your baby. You should not breastfeed during treatment with Lithium Oral Solution. Talk to your healthcare provider about the best way to feed your baby if you take Lithium.

Tell your healthcare provider about all the medicines you take,including prescription, over-the-counter medicines, vitamins, and herbal supplements.

Using Lithium with certain other medicines may affect each other causing possible side effects. Lithium may affect the way other medicines work, and other medicines may affect how Lithium works.

Especially tell your healthcare provider if you take:

• Take your Lithium Oral Solution exactly as prescribed by your healthcare provider.

• Your healthcare provider will do certain blood tests before starting and during treatment with Lithium Oral Solution.

• Your healthcare provider may change your dose if needed. Do notchange your dose on your own.

• Do notdouble your dose if a dose is missed. Talk with your healthcare provider if you miss a dose.

• Do notstop taking Lithium Oral Solution suddenly without talking to your healthcare provider.

• Your healthcare provider may change your Lithium Oral Solution dose to make sure you are taking the dose that is right for you.

• Do notdrive, operate heavy machinery, or do other dangerous activities when you start taking Lithium Oral Solution, when your dose is changed, or until you know how Lithium affects you. Lithium Oral Solution can make you sleepy. Talk to your healthcare provider about these activities.

• Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your healthcare provider instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

• kidney problems.People who take Lithium Oral Solution may have to urinate often (polyuria) and have other kidney problems that may affect how their kidneys work. These problems can happen within a few weeks of starting to take Lithium Oral Solution or after taking Lithium Oral Solution for a long time.

• low levels of sodium (salt) in your blood (hyponatremia).Lithium can cause you to lose sodium. Talk to your healthcare provider about your diet and how much fluid you are drinking when starting Lithium Oral Solution. If you have been sweating more than usual or have had diarrhea, you may need extra salt and more fluids. Talk to your healthcare provider if this happens.

• neurological problems. People who take Lithium Oral Solution with certain other medicines called antipsychotics may have symptoms such as weakness, tiredness, fever, tremors, and confusion. Talk to your healthcare provider if this happens. Ask if you are not sure about the medicines you take.

• serotonin syndrome.A potentially life-threatening problem called serotonin syndrome can happen when you take Lithium Oral Solution while you take certain medicines called serotonergic and MAOIs. Symptoms of serotonin syndrome include:

• thyroid problems.

• high calcium levels in your blood (hypercalcemia)and changes in your parathyroid gland (hyperparathyroidism) that may not go away when you stop taking Lithium.

• heart problems. People who take Lithium may find out they also have a heart problem called Brugada Syndrome. People who have unexplained fainting or who have a family history of sudden unexplained death before 45 years of age may have Brugada Syndrome and not know it. If you faint or feel abnormal heartbeats, talk to your healthcare provider right away.

• increased pressure in the brain and swelling in the eye (pseudotumor cerebri)that can cause vision problems or blindness. If you have severe headaches behind your eyes, ringing in the ears, blurred vision, double vision, or brief periods of blindness, talk to your health care provider right away.

The most common side effects of Lithium, include:

• Adults with manic or mixed episodes of bipolar I disorder:
  • hand trembling
  • excessive urination
  • increased thirst
  • nausea
  • general discomfort when you start treatment

• Children 7 to 17 years of age with manic or mixed episodes of bipolar I disorder:
  • excessive urination
  • thyroid problems
  • hand trembling
  • excessive thirst
  • dizziness
  • rash
  • difficulty walking
  • decreased appetite
  • blurred vision
  • nausea
  • vomiting