DESIPRAMINE HYDROCHLORIDE- desipramine hydrochloride tablet, film coated 
Actavis Pharma, Inc.

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Medication Guide

Desipramine Hydrochloride (des-IP-ra-meen HYE-droe-KLOR-ide) Tablets

Antidepressant Medicines, Depression and other Serious Mental Illnesses, and Suicidal Thoughts or Actions

Read the Medication Guide that comes with your or your family member’s, antidepressant medicine. This Medication Guide is only about the risk of suicidal thoughts and actions with antidepressant medicines. Talk to your or your family member’s, healthcare provider about:

What is the most important information I should know about antidepressant medicines, depression and other serious mental illnesses, and suicidal thoughts or actions?

  1. Antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment.
  2. Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions. Some people may have a particularly high risk of having suicidal thoughts or actions. These include people who have (or have a family history of) bipolar illness (also called manic-depressive illness) or suicidal thoughts or actions.
  3. How can I watch for and try to prevent suicidal thoughts and actions in myself or a family member?

Who should not take desipramine hydrochloride?

Call a healthcare provider right away if you or your family member has any of the following symptoms, especially if they are new, worse, or worry you:

• thoughts about suicide or dying • new or worse irritability
• attempts to commit suicide • acting aggressive, being angry, or violent
• new or worse depression • acting on dangerous impulses
• new or worse anxiety • an extreme increase in activity and talking (mania)
• feeling very agitated or restless • other unusual changes in behavior or mood
• panic attacks
• trouble sleeping (insomnia)

Visual Problems

 What else do I need to know about antidepressant medicines?

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

You may also report side effects to Actavis at 1-800-432-8534.

This Medication Guide has been approved by the U.S. Food and Drug Administration for all antidepressants.

Manufactured by:
Epic Pharma, LLC
Laurelton, NY 11413

Distributed by:
Actavis Pharma, Inc.
Parsippany, NJ 07054 USA

Rev. A 1/2019

Revised: 1/2019
Actavis Pharma, Inc.