TOPIRAMATE- topiramate tablet, film coated
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MEDICATION GUIDE

Topiramate (toe-PIR-a-mate) Tablets, USP

Topiramate (toe-PIR-a-mate) Capsules, USP

What is the most important information I should know about Topiramate?

Topiramate may cause eye problems. Serious eye problems include:

Topiramate may cause decreased sweating and increased body temperature (fever). People, especially children, should be watched for signs of decreased sweating and fever, especially in hot temperatures. Some people may need to be hospitalized for this condition. If a high fever, a fever that does not go away, or decreased sweating develops, call your healthcare provider right away.

Topiramate can increase the level of acid in your blood (metabolic acidosis). If left untreated, metabolic acidosis can cause brittle or soft bones (osteoporosis, osteomalacia, osteopenia), kidney stones, can slow the rate of growth in children, and may possibly harm your baby if you are pregnant. Metabolic acidosis can happen with or without symptoms. Sometimes people with metabolic acidosis will:

Your healthcare provider should do a blood test to measure the level of acid in your blood before and during your treatment with topiramate. If you are pregnant, you should talk to your healthcare provider about whether you have metabolic acidosis.

Call a healthcare provider right away if you have any of these symptoms, especially if they are new, worse, or worry you:

Do not stop topiramate without first talking to a healthcare provider.

How can I watch for early symptoms of suicidal thoughts and actions?

Topiramate can harm your unborn baby.

What is topiramate?

Topiramate is a prescription medicine used:

Before taking topiramate, tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Topiramate and other medicines may affect each other causing side effects.

Especially tell your healthcare provider if you take:

Ask your healthcare provider if you are not sure if your medicine is listed above.

Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist each time you get a new medicine. Do not start a new medicine without talking with your healthcare provider.

How should I take topiramate?

What should I avoid while taking topiramate?

What are the possible side effects of topiramate?

Topiramate may cause serious side effects including:

See "What is the most important information I should know about topiramate?"

Call your healthcare provider right away if you have any of the symptoms above.

The most common side effects of topiramate include:

Tell your healthcare provider about any side effect that bothers you or that does not go away. These are not all the possible side effects of topiramate.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store topiramate?

Keep topiramate and all medicines out of the reach of children.

General information about the safe and effective use topiramate.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use topiramate for a condition for which it was not prescribed. Do not give  topiramate to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about topiramate that is written for health professionals.

Please address medical inquiries to, MedicalAffairs@zydususa.com or Tel.: 1-877-993-8779.

What are the ingredients in topiramate?

Topiramate Tablets, USP

Active ingredient : topiramate, USP

Inactive ingredients : colloidal silicon dioxide, hypromellose, lactose anhydrous, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, talc and titanium dioxide.

Topiramate Capsules, USP

Active ingredient : topiramate, USP

Inactive ingredients : cellulose acetate, gelatin, hypromellose, povidone, sodium lauryl sulfate, sugar spheres, talc and titanium dioxide.

DEPAKENE ® and DEPAKOTE ® are registered trademarks of Abbott Laboratories.

This Medication Guide has been approved by the U.S. Food and Drug Administration.

This product's label may have been updated. For current full prescribing information, please visit www.zydususa.com.

Revised: 10/2019
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