NABUMETONE- nabumetone tablet, film coated 
Liberty Pharmaceuticals, Inc.


Medication Guide
Non-Steroidal Anti-inflammatory Drugs (NSAIDs)

(See the end of this Medication Guide for a list of prescription NSAID medicines.)

What is the most important information I should know about medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)?

NSAID medicines may increase the chance of a heart attack or stroke that can lead to death.This chance increases:

NSAID medicines should never be used right before or after a heart surgery called a “coronary artery bypass graft (CABG)” .

NSAID medicines can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Ulcers and bleeding:

The chance of a person getting an ulcer or bleeding increases with:

NSAID medicines should only be used:

What are Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)?

NSAID medicines are used to treat pain and redness, swelling, and heat (inflammation) from medical conditions such as:

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)?

Do not take an NSAID medicine:

Tell your healthcare provider:

What are the possible side effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)?

  Serious side effects include:  Other side effects include:
  • heart attack   • stomach pain
  • stroke   • constipation
  • high blood pressure   • diarrhea
  • heart failure from body swelling (fluid retention)   • gas
  • kidney problems including kidney failure   • heartburn
  • bleeding and ulcers in the stomach and intestine   • nausea
  • low red blood cells (anemia)   • vomiting
  • life-threatening skin reactions   • dizziness
  • life-threatening allergic reactions   
  • liver problems including liver failure   
  • asthma attacks in people who have asthma   

Get emergency help right away if you have any of the following symptoms:

  • shortness of breath or trouble breathing   • slurred speech
  • chest pain   • swelling of the face or throat
  • weakness in one part or side of your body    

Stop your NSAID medicine and call your healthcare provider right away if you have any of the following symptoms:

  • nausea   • there is blood in your bowel movement
   or it is black and sticky like tar
  • more tired or weaker than usual   • unusual weight gain
  • itching   • skin rash or blisters with fever
  • your skin or eyes look yellow   
  • stomach pain   • swelling of the arms and legs, hands and feet
  • flu-like symptoms   
  • vomit blood   

These are not all the side effects with NSAID medicines. Talk to your healthcare provider or pharmacist for more information about NSAID medicines.

Other information about Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

NSAID medicines that need a prescription

   Generic Name   Tradename
   Celecoxib    Celebrex
   Diclofenac    Cataflam, Voltaren, Arthrotec (combined with misoprostol)
   Diflunisal    Dolobid
   Etodolac    Lodine, Lodine XL
   Fenoprofen    Nalfon, Nalfon 200
   Flurbiprofen    Ansaid
   Ibuprofen    Motrin, Tab-Profen, Vicoprofen* (combined with hydrocodone), Combunox (combined with oxycodone)
   Indomethacin    Indocin, Indocin SR, Indo-Lemmon, Indomethagan
   Ketoprofen    Oruvail
   Ketorolac    Toradol
   Mefenamic Acid    Ponstel
   Meloxicam    Mobic
   Nabumetone    Relafen
   Naproxen    Naprosyn, Anaprox, Anaprox DS, EC-Naproxyn, Naprelan, Naprapac (copackaged with lansoprazole)
   Oxaprozin    Daypro
   Piroxicam    Feldene
   Sulindac    Clinoril
   Tolmetin    Tolectin, Tolectin DS, Tolectin 600

This Medication Guide has been approved by the U.S. Food and Drug Administration.
Rx only

Manufactured for:
Exelan Pharmaceuticals, Inc.
Lawrenceville, GA 30046

Manufactured by:
Ascent Pharmaceuticals, Inc.
Central Islip, NY 11722

Rev: 10/14

Revised: 8/2016
Liberty Pharmaceuticals, Inc.