MORPHINE SULFATE- morphine sulfate tablet 
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Morphine Sulfate (mor’ feen sul’ fate) Tablets CII
Rx only

Morphine Sulfate Tablets are:
  • A strong prescription pain medicine that contains an opioid (narcotic) that is used to manage short term (acute) and long term (chronic) pain severe enough to require an opioid pain medicine, when other pain treatments such as non-opioid pain medicines do not treat your pain well enough or you cannot tolerate them.
  • An opioid pain medicine that can put you at risk for overdose and death. Even if you take your dose correctly as prescribed you are at risk for opioid addiction, abuse, and misuse that can lead to death.

Important information about Morphine Sulfate Tablets:
  • Get emergency help right away if you take too much Morphine Sulfate Tablets (overdose). When you first start taking Morphine Sulfate Tablets, when your dose is changed, or if you take too much (overdose), serious or life-threatening breathing problems that can lead to death may occur.
  • Taking Morphine Sulfate Tablets with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, decreased awareness, breathing problems, coma, and death.
  • Never give anyone else your Morphine Sulfate Tablets. They could die from taking it. Selling or giving away Morphine Sulfate Tablets is against the law.
  • Store Morphine Sulfate Tablets securely, out of sight and reach of children, and in a location not accessible by others, including visitors to the home.

Do not take Morphine Sulfate Tablets if you have:
  • Severe asthma, trouble breathing, or other lung problems.
  • A bowel blockage or have narrowing of the stomach or intestines.
  • An allergy to morphine.

Before taking Morphine Sulfate Tablets, tell your healthcare provider if you have a history of:
  • Head injury, seizures.
  • Liver, kidney, thyroid problems.
  • Problems urinating.
  • Pancreas or gallbladder problems.
  • Abuse of street or prescription drugs, alcohol addiction, or mental health problems.

Tell your healthcare provider if you are:
  • Pregnant or planning to become pregnant. Prolonged use of morphine sulfate during pregnancy can cause withdrawal.
  • Breastfeeding. Morphine sulfate passes into breast milk and may harm your baby.
  • Taking prescription or over-the-counter medicines, vitamins, or herbal supplements. Taking Morphine Sulfate Tablets with certain other medicines can cause serious side effects that could lead to death.

When taking Morphine Sulfate Tablets:
  • Do not change your dose. Take Morphine Sulfate Tablets exactly as prescribed by your healthcare provider. Use the lowest dose possible for the shortest time needed.
  • Take your prescribed dose every 4 hours as needed for pain. Do not take more than your prescribed dose. If you miss a dose, take your next dose at your usual time.
  • Call your healthcare provider if the dose you are taking does not control your pain.
  • If you have been taking Morphine Sulfate Tablets regularly, do not stop taking morphine sulfate without talking to your healthcare provider.
  • Dispose of expired, unwanted, or unused Morphine Sulfate Tablets by promptly flushing down the toilet, if a drug take-back option is not readily available. Visit for additional information on disposal of unused medicines.

While taking Morphine Sulfate Tablets DO NOT:
  • Drive or operate heavy machinery, until you know how morphine sulfate affects you. Morphine Sulfate Tablets can make you sleepy, dizzy, or lightheaded.
  • Drink alcohol or use prescription or over-the-counter medicines that contain alcohol. Using products containing alcohol during treatment with Morphine Sulfate Tablets may cause you to overdose and die.

The possible side effects of Morphine Sulfate Tablets:
  • Constipation, nausea, sleepiness, vomiting, tiredness, headache, dizziness, abdominal pain. Call your healthcare provider if you have any of these symptoms and they are severe.

Get emergency medical help if you have:
  • Trouble breathing, shortness of breath, fast heartbeat, chest pain, swelling of your face, tongue, or throat, extreme drowsiness, light-headedness when changing positions, feeling faint, agitation, high body temperature, trouble walking, stiff muscles, or mental changes such as confusion.

These are not all the possible side effects of Morphine Sulfate Tablets. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. For more information go to

Manufactured by:
Alkem Laboratories
1733 Gilsinn Lane,
Fenton, MO 63026 

Distributed by:
Ascend Laboratories, LLC
Parsippany, NJ 07054
This Medication Guide has been approved by the U.S. Food and Drug Administration.

Revised: December, 2020

Revised: 11/2023
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