TICAGRELOR- ticagrelor tablet 
Amneal Pharmaceuticals NY LLC

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MEDICATION GUIDE

Ticagrelor (tye ka' grel or) Tablets

What is the most important information I should know about ticagrelor tablets?

Ticagrelor tablets are used to lower your chance of having a heart attack or dying from a heart attack or stroke but ticagrelor tablets (and similar drugs) can cause bleeding that can be serious and sometimes lead to death. In cases of serious bleeding, such as internal bleeding, the bleeding may result in the need for blood transfusions or surgery. While you take ticagrelor tablets:

Call your doctor right away, if you have any of these signs or symptoms of bleeding while taking ticagrelor tablets:

Do not stop taking ticagrelor tablets without talking to the doctor who prescribes it for you. People who are treated with a stent, and stop taking ticagrelor tablets too soon, have a higher risk of getting a blood clot in the stent, having a heart attack, or dying. If you stop ticagrelor tablets because of bleeding, or for other reasons, your risk of a heart attack or stroke may increase.

Your doctor may instruct you to stop taking ticagrelor tablets 5 days before surgery. This will help to decrease your risk of bleeding with your surgery or procedure. Your doctor should tell you when to start taking ticagrelor tablets again, as soon as possible after surgery.

Taking ticagrelor tablets with aspirin

Ticagrelor tablets are taken with aspirin. Talk to your doctor about the dose of aspirin that you should take with ticagrelor tablets. You should not take a dose of aspirin higher than 100 mg daily because it can affect how well ticagrelor tablets works. Do not take doses of aspirin higher than what your doctor tells you to take. Tell your doctor if you take other medicines that contain aspirin, and do not take new over-the-counter medicines with aspirin in them.

What are ticagrelor tablets?

Ticagrelor tablets are a prescription medicine used to treat people who:

Ticagrelor tablets are used with aspirin to lower your chance of having another serious problem with your heart or blood vessels, such as heart attack, stroke, or blood clots in your stent. These can be fatal.

Platelets are blood cells that help with normal blood clotting. Ticagrelor tablets help prevent platelets from sticking together and forming a clot that can block an artery.

It is not known if ticagrelor tablets are safe and effective in children.

Who should not take ticagrelor tablets?

Do not take ticagrelor tablets if you:

What should I tell my doctor before taking ticagrelor tablets?

Before you take ticagrelor tablets, tell your doctor if you:

Tell all of your doctors and dentists that you are taking ticagrelor tablets. They should talk to the doctor who prescribed ticagrelor tablets for you before you have any surgery or invasive procedure.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Ticagrelor tablets may affect the way other medicines work, and other medicines may affect how ticagrelor tablets works.

Especially tell your doctor if you take:

Ask your doctor or pharmacist if you are not sure if your medicine is listed above.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

How should I take ticagrelor tablets?

If you are unable to swallow the tablet(s) whole, you may crush the ticagrelor tablet(s) and mix it with water. Drink all the water right away. Refill the glass with water, stir and drink all the water.

What are the possible side effects of ticagrelor tablets?

Ticagrelor tablets can cause serious side effects, including:

These are not all of the possible side effects of ticagrelor tablets. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store ticagrelor tablets?

Keep ticagrelor tablets and all medicines out of the reach of children.

General information about ticagrelor tablets

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use ticagrelor tablets for a condition for which it was not prescribed. Do not give ticagrelor tablets to other people, even if they have the same symptoms you have. It may harm them. You can ask your pharmacist or doctor for information about ticagrelor tablets that is written for health professionals.

What are the ingredients in ticagrelor tablets?

Active ingredient: ticagrelor

Inactive ingredients: colloidal silicon dioxide, crospovidone, hypromellose, iron oxide yellow, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone, sodium starch glycolate, talc and titanium dioxide.

For more information call 1-877-835-5472 or go to www.amneal.com.

This Medication Guide has been approved by the U.S. Food and Drug Administration.

All trademarks are property of their respective owners.

Manufactured by:
Amneal Pharmaceuticals Pvt. Ltd.
Oral Solid Dosage Unit

Ahmedabad 382213, INDIA

Distributed by:
Amneal Pharmaceuticals LLC

Bridgewater, NJ 08807

Rev. 04-2019-01

Revised: 4/2019
Amneal Pharmaceuticals NY LLC