DUOPA- carbidopa and levodopa suspension 
AbbVie Inc.



DUOPA (Do-oh-pa)

(carbidopa and levodopa) enteral suspension

Read this Medication Guide before you start using DUOPA and each time you get a refill. There may be new information. This information does not take the place of talking to your healthcare provider about your medical condition or treatment.

What is the most important information I should know about DUOPA?

DUOPA can cause serious side effects, including:

You will need to have a procedure to make a small hole (called a “stoma”) in your stomach wall to place a gastro-jejunostomy tube (called a PEG-J tube) in an area of your small intestine called the jejunum. DUOPA is delivered directly to your small intestine through this tube. Your healthcare provider will talk to you about the stoma procedure. Before the stoma procedure, tell your healthcare provider if you have ever had a surgery or problems with your stomach.

Talk to your healthcare provider about what you need to do to care for your stoma. After the procedure, you and your healthcare provider will need to regularly check the stoma for any signs of infection.

If your PEG-J tube becomes kinked, knotted, or blocked this may cause you to have worsening of your Parkinson’s symptoms or recurring movement problems (motor fluctuations). Call your healthcare provider if your Parkinson’s symptoms get worse or you have slow movement while you are treated with DUOPA.

What is DUOPA?

DUOPA is a prescription medicine used for treatment of advanced Parkinson's disease. DUOPA contains 2 medicines, carbidopa and levodopa.

DUOPA should not be given to children (younger than 18 years).

Who should not use DUOPA?

Do not use DUOPA if you:

What should I tell my healthcare provider before using DUOPA?

Before you use DUOPA, tell your healthcare provider if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements.

Using DUOPA with certain other medicines may affect each other and cause serious side effects.

Especially tell your healthcare provider if you take:

Eating high protein foods may affect how DUOPA works. Tell your healthcare provider if you change your diet.

Ask your healthcare provider or pharmacist for a list of these medicines or foods if you are not sure.

Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

How should I use DUOPA?

What should I avoid while using DUOPA?

What are the possible side effects of DUOPA?

DUOPA may cause serious side effects, including:

Call your healthcare provider or get medical care right away if you have any of the above symptoms. Your healthcare provider will tell you if you should stop treatment with DUOPA and if needed, tell you how to discontinue DUOPA.

Tell your healthcare provider if you have any side effect that bothers you or does not go away.

These are not all of the possible side effects of DUOPA. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store DUOPA?

Keep DUOPA and all medicines out of the reach of children.

General information about the safe and effective use of DUOPA.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use DUOPA for a condition for which it was not prescribed. Do not give DUOPA to other people, even if they have the same symptoms that you have. It may harm them.

This Medication Guide summarizes the most important information about DUOPA. If you would like more information, talk with your healthcare provider. You can ask your healthcare provider or pharmacist for information about DUOPA that was written for healthcare professionals.

For more information go to www.DUOPA.com or call 1-844-386-4968.

What are the ingredients in DUOPA?

Active ingredients: carbidopa and levodopa

Inactive ingredients: carmellose sodium and purified water

This Medication Guide has been approved by the U.S. Food and Drug Administration.

Manufactured by AbbVie Inc., North Chicago, IL 60064, USA
or by Fresenius Kabi Norge AS, 1788 Halden, Norway
For AbbVie Inc.
North Chicago, IL 60064, USA

© 2019-2022 AbbVie Inc.
20070164 Revised: March 2022

Revised: 3/2022
AbbVie Inc.