COLCHICINE- colchicine tablet, film coated 
Mylan Institutional Inc.

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Medication Guide

Colchicine Tablets, USP
(kol' chi seen)

Read the Medication Guide that comes with colchicine tablets before you start taking it and each time you get a refill. There may be new information. This Medication Guide does not take the place of talking to your healthcare provider about your medical condition or treatment. You and your healthcare provider should talk about colchicine tablets when you start taking them and at regular checkups.

What is the most important information that I should know about colchicine tablets?

Colchicine tablets can cause serious side effects or death if levels of colchicine are too high in your body.

  • atazanavir sulfate (Reyataz ®)
  • cyclosporine (Neoral ®, Gengraf ®, Sandimmune ®)
  • fosamprenavir (Lexiva ®) with ritonavir
  • indinavir (Crixivan ®)
  • ketoconazole (Nizoral ®)
  • nefazodone (Serzone ®)
  • ritonavir (Norvir ®)
  • telithromycin (Ketek ®)
  • clarithromycin (Biaxin ®)
  • darunavir (Prezista ®)
  • fosamprenavir (Lexiva ®)
  • itraconazole (Sporanox ®)
  • lopinavir/ritonavir (Kaletra ®)
  • nelfinavir mesylate (Viracept ®)
  • saquinavir mesylate (Invirase ®)
  • tipranavir (Aptivus ®)

Ask your healthcare provider or pharmacist if you are not sure if you take any of the medicines listed above. This is not a complete list of all the medicines that can interact with colchicine tablets.

What are colchicine tablets?

Colchicine tablets are a prescription medicine used to:

Colchicine tablets are not a pain medicine, and it should not be taken to treat pain related to other conditions unless specifically prescribed for those conditions.

Who should not take colchicine tablets?

Do not take colchicine tablets if you have liver or kidney problems and you take certain other medicines. Serious side effects, including death, have been reported in these patients even when taken as directed. See “What is the most important information that I should know about colchicine tablets?”

What should I tell my healthcare provider before starting colchicine tablets? See “What is the most important information that I should know about colchicine tablets?”

Before you take colchicine tablets, tell your healthcare provider about all your medical conditions, including if you:

Tell your healthcare provider about all the medicines you take, including ones that you may only be taking for a short time, such as antibiotics. See “What is the most important information that I should know about colchicine tablets?” Do not start a new medicine without talking to your healthcare provider.

Using colchicine tablets with certain other medicines, such as cholesterol-lowering medications and digoxin, can affect each other, causing serious side effects. Your healthcare provider may need to change your dose of colchicine tablets. Talk to your healthcare provider about whether the medications you are taking might interact with colchicine tablets and what side effects to look for.

How should I take colchicine tablets?

What should I avoid while taking colchicine tablets?

What are the possible side effects of colchicine tablets?

Colchicine tablets can cause serious side effects or even cause death. See “What is the most important information that I should know about colchicine tablets?”

Get medical help right away if you have:

Gout Flares: The most common side effect of colchicine tablets in people who have gout flares is diarrhea.

FMF: The most common side effects of colchicine tablets in people who have FMF are abdominal pain, diarrhea, nausea and vomiting.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all of the possible side effects of colchicine tablets. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store colchicine tablets?

Keep colchicine tablets and all medicines out of the reach of children.

General Information about colchicine tablets

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use colchicine tablets for a condition for which it was not prescribed. Do not give colchicine tablets to other people, even if they have the same symptoms that you have. It may harm them. This Medication Guide summarizes the most important information about colchicine tablets. If you would like more information, talk with your healthcare provider. You can ask your healthcare provider or pharmacist for information about colchicine tablets that is written for healthcare professionals.

For more information, call Mylan Pharmaceuticals Inc. at 1-877-446-3679 (1-877-4-INFO-RX).

What are the ingredients in colchicine tablets?

Active Ingredient: colchicine.

Inactive Ingredients: hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch (corn), polydextrose, polyethylene glycol, red iron oxide, sodium starch glycolate (potato), titanium dioxide and yellow iron oxide.

This Medication Guide has been approved by the U.S. Food and Drug Administration.

The brands listed are trademarks of their respective owners.

Manufactured by:
Mylan Pharmaceuticals Inc.
Morgantown, WV 26505 U.S.A.

Distributed by:
Mylan Institutional Inc.
Rockford, IL 61103 U.S.A.

S-12589
8/19

Revised: 5/2020
Mylan Institutional Inc.