IMIPRAMINE HYDROCHLORIDE- imipramine hydrochloride tablet, film coated 
Lupin Pharmaceuticals, Inc.



Imipramine Hydrochloride Tablets


Antidepressant Medicines, Depression and other Serious Mental Illnesses, and Suicidal Thoughts or Actions

Rx only

Read the Medication Guide that comes with you or your family member's antidepressant medicine. This Medication Guide is only about the risk of suicidal thoughts and actions with antidepressant medicines. Talk to your, or your family member's, healthcare provider about:

What is the most important information I should know about antidepressant medicines, depression and other serious mental illnesses, and suicidal thoughts or actions?

  1. Antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment.
  2. Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions. Some people may have a particularly high risk of having suicidal thoughts or actions.These include people who have (or have a family history of) bipolar illness (also called manic-depressive illness) or suicidal thoughts or actions.
  3. How can I watch for and try to prevent suicidal thoughts and actions in myself or a family member?

Call a healthcare provider right away if you or your family member has any of the following symptoms, especially if they are new, worse, or worry you:

thoughts about suicide or dying 
new or worse irritability 
attempts to commit suicide 
acting aggressive, being angry, or violent 
new or worse depression 
acting on dangerous impulses 
new or worse anxiety 
an extreme increase in activity and talking (mania)
feeling very agitated or restless 
other unusual changes in behavior or mood
panic attacks
Visual problemseye pain, changes in vision, swelling or redness in or around the eye
trouble sleeping (insomnia)

Who should not take imipramine hydrochloride tablets?

Do not take imipramine hydrochloride tablets if you:

What else do I need to know about antidepressant medicines? 

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

You may also report side effects to Lupin Pharmaceuticals, Inc. at 1-800-399-2561.

This Medication Guide has been approved by the U.S. Food and Drug Administration.

Manufactured for:

Lupin Pharmaceuticals, Inc.

Baltimore, Maryland 21202

United States


Manufactured by:

Lupin Limited

Goa 403 722


Revised: April 2016                                                                                   ID#: 245395

Revised: 12/2023
Lupin Pharmaceuticals, Inc.