MITOXANTRONE- mitoxantrone injection, solution, concentrate 
Teva Parenteral Medicines, Inc.



Injection USP (concentrate)

Read this medication guide before you start receiving mitoXANTRONE and each time you receive mitoXANTRONE. There may be new information. This information does not take the place of talking to your doctor about your medical condition or your treatment.

What is the most important information I should know about mitoXANTRONE?

mitoXANTRONE can cause serious side effects, including:

Before receiving mitoXANTRONE for the first time, you should have the following tests done:

If you receive mitoXANTRONE to treat Multiple Sclerosis (MS), your doctor should also do the tests above:

What is mitoXANTRONE?

mitoXANTRONE is a prescription medicine used alone or with other medicines to treat people with:

mitoXANTRONE is not for people with primary progressive MS.

It is not known if mitroXANTRONE is safe and effective in children.

Who should not receive mitoXANTRONE?

Do not receive mitoXANTRONE if you are allergic to mitoXANTRONE or any of the ingredients in mitoXATRONE. See the end of this medication guide for a complete list of ingredients in mitoXATRONE.

What should I tell my doctor before receiving mitoXANTRONE?

Before you receive mitoXANTRONE, tell your doctor if you have:

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Using mitoXANTRONE with certain other medicines may cause serious side effects.

Especially tell your doctor if you take or have taken:

Ask your doctor or pharmacist for a list of these medicines if you are not sure if you take or have taken any of these medicines.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

How should I receive mitoXANTRONE?

What are the possible side effects of mitoXANTRONE?

mitoXANTRONE may cause serious side effects, including:

The most common side effects of mitoXANTRONE include:

Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of mitoXANTRONE. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

General information about the safe and effective use of mitoXANTRONE.

Medicines are sometimes prescribed for purposes other than those listed in a medication guide.

This Medication Guide summarizes the most important information about mitoXANTRONE. If you would like more information, talk with your doctor. You can ask your pharmacist or doctor for information about mitoXANTRONE that is written for health professionals.

For more information, call 1-800-227-7522.

What are the ingredients in mitoXANTRONE?

Active ingredient: mitoXANTRONE hydrochloride USP

Inactive ingredients: sodium chloride, sodium acetate anhydrous, glacial acetic acid and water for injection

This Medication Guide has been approved by the U.S. Food and Drug Administration.

Rev. C 5/2012

Teva Parenteral Medicines, Inc.
Irvine, CA 92618

Revised: 10/2021
Teva Parenteral Medicines, Inc.