Administration

Lansoprazole is available as capsules in 15 mg and 30 mg strengths. Direction for use specific to the route and available methods of administration of this dosage form is presented below [see Dosage and Administration ( 2.3) ].

• Lansoprazole should be taken before eating.
• Lansoprazole delayed-release capsules SHOULD NOT BE CRUSHED OR CHEWED.

Administration Options

Lansoprazole Delayed-release Capsules – Oral Administration

• Lansoprazole delayed-release capsules should be swallowed whole.
• Alternatively, for patients who have difficulty swallowing capsules, lansoprazole delayed-release capsules can be opened and administered as follows:

      о   Open capsule.

      о   Sprinkle intact granules on one tablespoon of either applesauce, ENSURE pudding, cottage cheese, yogurt or strained pears.

      о   Swallow immediately.

• Lansoprazole delayed-release capsules may also be emptied into a small volume of either apple juice, orange juice or tomato juice and administered as follows:

      о   Open capsule.

      о   Sprinkle intact granules into a small volume of either apple juice, orange juice or tomato juice (60 mL – approximately two ounces).

      о   Mix briefly.

      о   Swallow immediately.

      о   To ensure complete delivery of the dose, the glass should be rinsed with two or more volumes of juice and the contents swallowed immediately.

Lansoprazole delayed-release capsules - Nasogastric Tube (≥ 16 French) Administration

• For patients who have a nasogastric tube in place, lansoprazole delayed-release capsules can be administered as follows:

      о   Open capsule.

      о   Mix intact granules into 40 mL of apple juice. DO NOT USE OTHER LIQUIDS.

      о   Inject through the nasogastric tube into the stomach.

      о   Flush with additional apple juice to clear the tube.

USE IN OTHER FOODS AND LIQUIDS HAS NOT BEEN STUDIED CLINICALLY AND IS THEREFORE NOT RECOMMENDED.

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