HYDROCORTISONE- hydrocortisone enema 
ANI Pharmaceuticals, Inc.



How to use the retention enema:
Best results are achieved if the bowel is emptied immediately before the enema is given.

1.  Preparing the Medication for Administration
a Shake the bottle well to make sure that the suspension is homogeneous.
b Remove the protective sheath from the applicator tip. Hold the bottle at the neck so as not to cause any of the medication to be discharged.

Step 1b Image

2.  Assuming the Correct Body Position
a Best results are obtained by lying on left side with the left leg extended and the right leg flexed forward for balance.

Step 2a Image

b An alternative to lying on the left side is the “knee-chest” position as shown here.

Step 2b Image

3.  Administering the Retention Enema
a Gently insert the lubricated applicator tip into the rectum, pointed slightly toward the navel (umbilicus).
b Grasp the bottle firmly, then tilt slightly so that the nozzle is aimed toward the back, and squeeze slowly to instill the medication. Steady hand pressure will discharge most of the solution. After administering, withdraw and discard the used unit.

Step 3b Image

c  Remain in position for at least 30 minutes to allow thorough distribution of the medication internally. Retain the enema all night, if possible.

Manufactured by
ANI Pharmaceuticals, Inc.
Baudette, MN 56623
9247 Rev 11/11

Revised: 11/2018
ANI Pharmaceuticals, Inc.