SELZENTRY - maraviroc tablet, film coated 
Physicians Total Care, Inc.



SELZENTRY® (sell-ZEN-tree) Tablets

Read the Medication Guide that comes with SELZENTRY before you start taking it and each time you get a refill. There may be new information. This information does not take the place of talking with your health care provider about your medical condition or treatment.

What is the most important information I should know about SELZENTRY?

Serious side effects have occurred with SELZENTRY, including liver problems (liver toxicity). An allergic reaction may happen before liver problems occur. Stop taking SELZENTRY and call your health care provider right away if you get any of the following symptoms:


SELZENTRY is an anti-HIV medicine called a CCR5 antagonist. HIV (Human Immunodeficiency Virus) is the virus that causes AIDS (Acquired Immune Deficiency Syndrome).

SELZENTRY is used with other anti-HIV medicines in adults with CCR5-tropic HIV-1 infection.

Use of SELZENTRY is not recommended in people with dual/mixed or CXCR4-tropic HIV-1.

SELZENTRY has not been studied in children less than 16 years of age.

Does SELZENTRY lower the risk of passing HIV to other people?

No, SELZENTRY does not lower the risk of passing HIV to other people through sexual contact, sharing needles, or being exposed to your blood.

How does SELZENTRY work?

HIV enters cells in your blood by attaching itself to structures on the surface of the cell called receptors. SELZENTRY blocks a specific receptor called CCR5 that CCR5-tropic HIV-1 uses to enter CD4 or T-cells in your blood. Your health care provider will do a blood test to see if you have been infected with CCR5-tropic HIV-1 before prescribing SELZENTRY for you.

SELZENTRY does not work in all people with CCR5-tropic HIV-1 infection.

Who should not take SELZENTRY?

People with severe kidney problems or who are on hemodialysis and are taking certain other medications should not take SELZENTRY. Talk to your healthcare provider before taking this medicine if you have kidney problems.

What should I tell my health care provider before taking SELZENTRY?

Before you take SELZENTRY, tell your health care provider if you:

Tell your health care provider about all the medicines you take, including prescription and non-prescription medicines, vitamins and herbal supplements. Certain other medicines may affect the levels of SELZENTRY in your blood. Your health care provider may need to change your dose of SELZENTRY when you take it with certain medicines.

The levels of SELZENTRY in your blood may change and your health care provider may need to adjust your dose of SELZENTRY when taking any of the following medications together with SELZENTRY:

darunavir (Prezista®)
lopinavir/ritonavir (Kaletra®, Norvir®)
atazanavir (Reyataz®)
saquinavir (Invirase®)
nelfinavir (Viracept®)
indinavir (Crixivan®)
fosamprenavir (Lexiva®)
etravirine (Intelence®)
carbamezepine (Tegretol®)
phenytoin (Dilantin®)
Ritonavir (Norvir®)
delavirdine (Rescriptor®)
ketoconazole (Nizoral®)
itraconazole (Sporanox®)
clarithromycin (Biaxin®)
nefazodone (Serzone®)
telithromycin (Ketek®)
efavirenz (Sustiva®, Atripla®)
rifampin (Rifadin®, Rifater®)
phenobarbital (Luminal®)

Do not take products that contain St. John's Wort (hypericum perforatum). St. John's Wort may lower the levels of SELZENTRY in your blood so that it will not work to treat your CCR5-tropic HIV infection.

Know the medicines you take. Keep a list of your medicines. Show the list to your health care provider and pharmacist when you get a new medicine.

How should I take SELZENTRY?

Take SELZENTRY exactly as prescribed by your health care provider. SELZENTRY comes in 150 mg and 300 mg tablets. Your health care provider will prescribe the dose that is right for you.

Do not change your dose or stop taking SELZENTRY or your other anti-HIV medicines without first talking with your health care provider.

What are the possible side effects of SELZENTRY?

There have been serious side effects when SELZENTRY has been given with other anti-HIV drugs including:

The most common side effects of SELZENTRY include colds, cough, fever, rash, and dizziness.

Tell your health care provider about any side effect that bothers you or does not go away.

These are not all of the side effects with SELZENTRY. For more information, ask your health care provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store SELZENTRY?

Keep SELZENTRY and all medicines out of the reach of children.

General information about SELZENTRY

Medicines are sometimes prescribed for conditions that are not mentioned in Medication Guides. Do not use SELZENTRY for a condition for which it was not prescribed. Do not give SELZENTRY to other people, even if they have the same symptoms you have. It may harm them.

This Medication Guide summarizes the most important information about SELZENTRY. If you would like more information, talk with your health care provider. You can ask your health care provider or pharmacist for more information about SELZENTRY that is written for health professionals. For more information, go to

What are the ingredients in SELZENTRY?

Active ingredient: maraviroc

Inactive ingredients: microcrystalline cellulose, dibasic calcium phosphate (anhydrous), sodium starch glycolate, magnesium stearate
Film-coat: FD&C blue #2 aluminum lake, soya lecithin, polyethylene glycol (macrogol 3350), polyvinyl alcohol, talc and titanium dioxide

The brands listed are the trademarks or registered marks of their respective owners and are not trademarks of Pfizer.

This Medication Guide has been approved by the US Food and Drug Administration.

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May 2010

Revised: 5/2012
Physicians Total Care, Inc.