DULOXETINE- duloxetine capsule, delayed release pellets 
Medsource Pharmaceuticals



DULOXETINE [doh-LOCKS-ah-teen]

(Duloxetine Delayed-Release Capsules USP)

Read the Medication Guide that comes with duloxetine before you start taking it and each time you get a refill. There may be new information. This Medication Guide does not take the place of talking to your healthcare provider about your medical condition or treatment. Talk with your healthcare provider if there is something you do not understand or want to learn more about. 

What is the most important information I should know about duloxetine delayed-release capsules?  

Duloxetine and other antidepressant medicines may cause serious side effects, including:  

1. Suicidal thoughts or actions:

Keep all follow-up visits with your healthcare provider and call between visits if you are worried about symptoms.  

Call your healthcare provider right away if you have any of the following symptoms, or call 911 if an emergency, especially if they are new, worse, or worry you:

Call your healthcare provider right away if you have any of the following symptoms, or call 911 if an emergency. Duloxetine  may be associated with these serious side effects:  

2. Liver damage- symptoms may include:

3. Serotonin Syndrome -This condition can be life-threatening and may include.

4. Abnormal bleeding: Duloxetine  and other antidepressant medicines may increase your risk of bleeding or bruising, especially if you take the blood thinner warfarin (Coumadin*, Jantoven*), a non-steroidal anti-inflammatory drug (NSAIDs, like ibuprofen or naproxen), or aspirin.  

5. Severe skin reactions: Duloxetine  may cause serious skin reactions that may require stopping its use. This may need to be treated in a hospital and may be life-threatening. Call your doctor right away or get emergency help if you have skin blisters, peeling rash, sores in the mouth, hives or any other allergic reactions.  

6. Manic episodes:

7. Visual Problems

Only some people are at risk for these problems. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are.

8. Seizures or convulsions  

9. Changes in blood pressure. Monitor your blood pressure before starting and throughout treatment. Duloxetine  may:  


10. Low salt (sodium) levels in the blood. Elderly people may be at greater risk for this. Symptoms may include:

11. Problems with urination include:


12. Changes in appetite or weight. Children and adolescents should have height and weight monitored during treatment.  

Do not stop duloxetine delayed-release capsules without first talking to your healthcare provider. Stopping duloxetine delayed-release capsules too quickly or changing from another antidepressant too quickly may result in serious symptoms including:

What is duloxetine ?

Duloxetine  is a prescription medicine used to treat depression. It is important to talk with your healthcare provider about the risks of treating depression and also the risks of not treating it. You should discuss all treatment choices with your healthcare provider. Duloxetine  is also used to treat or manage:

 Talk to your healthcare provider if you do not think that your condition is getting better with duloxetine treatment.  

Who should not take duloxetine delayed-release capsules?

Do NOT take duloxetine delayed-release capsules if you:


What should I tell my healthcare provider before taking duloxetine delayed-release capsules? Ask if you are not sure.

Before starting duloxetine , tell your healthcare provider if you:


Tell your healthcare provider about all the medicines that you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Duloxetine  and some medicines may interact with each other, may not work as well, or may cause serious side effects.  

Your healthcare provider or pharmacist can tell you if it is safe to take duloxetine  with your other medicines. Do not start or stop any medicine while taking duloxetine  without talking to your healthcare provider first.

If you take duloxetine delayed-release capsules, you should not take any other medicines that contain duloxetine.  

How should I take duloxetine delayed-release capsules?

What should I avoid while taking duloxetine delayed-release capsules?


What are the possible side effects of duloxetine delayed-release capsules?

Duloxetine  may cause serious side effects, including all of those described in the section entitled “ What is the most important information I should know about duloxetine delayed-release capsules?  

Common possible side effects in people who take duloxetine  include:

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of duloxetine. For more information, ask your healthcare provider or pharmacist.


How should I store duloxetine delayed-release capsules?

Store at 20°-25°C (68° - 77°F); [See USP Controlled Room Temperature].

Keep duloxetine delayed-release capsules and all medicines out of the reach of children. 

General information about duloxetine  

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use duloxetine  for a condition for which it was not prescribed. Do not give duloxetine to other people, even if they have the same condition. It may harm them.  

This Medication Guide summarizes the most important information about duloxetine. If you would like more information, talk with your healthcare provider. You may ask your healthcare provider or pharmacist for information about duloxetine  that is written for healthcare professionals.  For more information about duloxetine call 1-888-375-3784. 

What are the ingredients in duloxetine delayed-release capsules?

Active ingredient: duloxetine hydrochloride USP

Inactive ingredients: ammonia, FD&C Blue 2, gelatin, glycine, hypromellose phthalate, hypromellose, iron oxide yellow, propylene glycol, shellac, sodium lauryl sulfate, sucrose, sugar spheres (contains sugar and corn starch), talc, titanium dioxide, and triethyl citrate. The 20 mg capsules also contain black iron oxide and potassium hydroxide. The 60 mg capsules also contain potassium hydroxide. 

This Medication Guide has been approved by the U.S. Food and Drug Administration.

To reorder additional Medication Guides, please contact Dr. Reddy's Customer Service at 1-866-733-3952

* The brands listed are trademarks of their respective owners and not trademarks of Dr. Reddy’s Laboratories Limited.

Rx only

Manufactured by
Dr. Reddy’s Laboratories Limited
Bachupally – 500 090 INDIA 

Revised: 0914

Revised: 12/2019
Medsource Pharmaceuticals