ExeGen MYH7 miniswine

ExeGen MYH7 miniswine are genetically engineered yucatan miniature swine containing the rDNA construct pMYH7-Blast which exhibit similar phenotypes to human patients with HCM. These pigs are intended to be used as large animal models of the human disease. We will not be requesting a food use authorization and the carcasses and all materials generated from these animals will be destroyed by incineration.

Product Definition: A specific line of Yucatan miniature pigs (Sus scrofa domesticus), including heterozygous offspring resulting from a heterozygous founder, in which the MYH7 gene has been disrupted by the homologous recombination of a single copy of a mutated MYH7-PGK construct resulting in the mutation R403Q for use in biomedical research. The final sellable animal well be a heterozygote MYH7 +/R403Q Blast Excised miniswine.

Warning: This product is from a genetically engineered animal and may contain an investigational new animal drug. It is for research purposes only and not for use in humans or as food/feed unless authorization has been granted by the US Food and Drug Administration. In case of emergency release contact Exemplar Genetics at 712-722-2767 or 712-441-3408.