ALKA-SELTZER ORIGINAL- anhydrous citric acid, aspirin, and sodium bicarbonate tablet, effervescent 
R J General Corporation

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.


Alka-Seltzer ® Original

Drug Facts

Active ingredients (in each tablet)Purpose
nonsteroidal anti-inflammatory drug
Anhydrous citric acid 1000 mgAntacid
Aspirin 325 mg (NSAID) *Analgesic
Sodium bicarbonate (heat-treated) 1916 mgAntacid


for the temporary relief of:


Reye's syndrome

Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness.

Allergy alert

Aspirin may cause a severe allergic reaction which may include:

  • hives
  • facial swelling
  • asthma (wheezing)
  • shock

Stomach bleeding warning

This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you

  • are age 60 or older
  • have had stomach ulcers or bleeding problems
  • take a blood thinning (anticoagulant) or steroid drug
  • take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others)
  • have 3 or more alcoholic drinks every day while using this product
  • take more or for a longer time than directed

Do not use

  • if you are allergic to aspirin or any other pain reliever/fever reducer
  • if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use if

  • stomach bleeding warning applies to you
  • you have a history of stomach problems, such as heartburn
  • you have high blood pressure, heart disease, liver cirrhosis, or kidney disease
  • you are taking a diuretic
  • you have asthma
  • you have a sodium-restricted diet

Ask a doctor or pharmacist before use if you are

  • presently taking a prescription drug. Antacids may interact with certain prescription drugs.
  • taking a prescription drug for diabetes, gout, or arthritis

When using this product do not exceed recommended dosage

Stop use and ask a doctor if

  • an allergic reaction occurs. Seek medical help right away.
  • you experience any of the following signs of stomach bleeding
    • feel faint
    • vomit blood
    • have bloody or black stools
    • have stomach pain that does not get better
  • symptoms get worse or last more than 10 days
  • redness or swelling is present
  • ringing in the ears or a loss of hearing occurs
  • new symptoms occur

If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.



● fully dissolve 2 tablets in 4 ounces of water before taking

adults and children 12 years and over2 tablets every 4 hours, or as directed by a doctordo not exceed 8 tablets in 24 hours
adults 60 years and over2 tablets every 4 hours, or as directed by a doctordo not exceed 4 tablets in 24 hours
children under 12 yearsconsult a doctor

Other information

Inactive ingredients


Questions or comments?

1-800-986-0369 (Mon – Fri 9AM – 5PM EST)

Dist. by: Bayer HealthCare LLC
Whippany, NJ 07981

PRINCIPAL DISPLAY PANEL - 100 Tablet Pouch Carton

Seltzer ®

Anhydrous citric acid / Antacid
Aspirin ( NSAID) / Analgesic
Sodium bicarbonate / Antacid

Fast Relief of:
Upset Stomach
Acid Indigestion
with Headache
Body Aches


Principal Display Panel - 100 Tablet Pouch Carton
anhydrous citric acid, aspirin, and sodium bicarbonate tablet, effervescent
Product Information
Product TypeHUMAN OTC DRUGItem Code (Source)NDC:70264-014(NDC:0280-4000)
Route of AdministrationORAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Product Characteristics
ColorwhiteScoreno score
FlavorImprint Code ALKA;SELTZER
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:70264-014-0150 in 1 CARTON03/02/2010
12 in 1 POUCH; Type 0: Not a Combination Product
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC monograph not finalpart34303/02/2010
Labeler - R J General Corporation (122542830)
NameAddressID/FEIBusiness Operations
R J General Corporation122542830repack(70264-014)

Revised: 12/2022
Document Id: eff0fb51-f837-2561-e053-2995a90ae8d4
Set id: dbb0d067-71f0-45e4-bc98-548cf4a90b3a
Version: 3
Effective Time: 20221216
R J General Corporation