Active ingredients

Carboxymethylcellulose sodium 0.5%
Glycerin 1%
Polysorbate 80 0.5%

Purpose

Eye lubricant
Eye lubricant
Eye lubricant

Uses

For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun.
May be used as a protectant against further irritation.

Warnings

For external use only.
To avoid contamination, do not touch tip of container to any surface. Do not reuse. Once opened, discard.
Do not touch unit-dose tip to eye.
If solution changes color, do not use.

Stop use and ask a doctor if

you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.

Keep out of reach of children.

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

To open, TWIST AND PULL TAB TO REMOVE. Instill 1 or 2 drops in the affected eye(s) as needed and discard container.

Other information

Use only if single-use container is intact.
Use before expiration date marked on container.
Store at 59°-77°F (15°-25°C).
Store vials in the pouch until use.
RETAIN THIS CARTON FOR FUTURE REFERENCE.

Inactive ingredients

Boric acid; butylated hydroxyl toluene; carbomer copolymer type A; castor oil; erythritol; flaxseed oil; levocarnitine; polyoxyl 40 stearate; purified water; and trehalose. May contain hydrochloric acid and/or sodium hydroxide (to adjust pH).

Questions or comments?

1.800.678.1605
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PRINCIPAL DISPLAY PANEL

NDC 0023-5773-30

Preservative-free
Refresh
Optive®
MEGA-3
Lubricant Eye Drops
ENHANCED WITH FLAXSEED OIL
Prevents tear evaporation and restores all
three layers of the tear film damaged by Dry Eye.
30 Single-Use Containers
0.01 fl oz (0.4 mL) each Sterile

NDC 0023-5773-30
Preservative-free
Refresh
Optive®
MEGA-3
Lubricant Eye Drops
ENHANCED WITH FLAXSEED OIL
Prevents tear evaporation and restores all
three layers of the tear film damaged by Dry Eye.
30 Single-Use Containers
0.01 fl oz (0.4 mL) each Sterile

PRINCIPAL DISPLAY PANEL

NDC 0023-7151-60

VALUE SIZE 60 Vials

PRESERVATIVE-FREE
Refresh
OPTIVE
MEGA-3®
Lubricant Eye Drops
For Eye Dryness

with HydroCell™

Moisture-rich Relief
Protects Tears from Evaporating

60 Vials 0.01 fl oz (0.4 mL) each Sterile

NDC 0023-7151-60
VALUE SIZE 60 Vials
PRESERVATIVE-FREE
Refresh
OPTIVE
MEGA-3®
Lubricant Eye Drops
For Eye Dryness
with HydroCell™
Moisture-rich Relief
Protects Tears from Evaporating
60 Vials 0.01 fl oz (0.4 mL) each Sterile

REFRESH OPTIVE MEGA-3
carboxymethylcellulose sodium, glycerin and polysorbate 80 solution/ drops

Product Information
Product Type	HUMAN OTC DRUG	Item Code (Source)	NDC:0023-7151
Route of Administration	OPHTHALMIC

Ingredient Name	Basis of Strength	Strength
Active Ingredient/Active Moiety
CARBOXYMETHYLCELLULOSE SODIUM (UNII: K679OBS311) (CARBOXYMETHYLCELLULOSE - UNII:05JZI7B19X)	CARBOXYMETHYLCELLULOSE SODIUM	5 mg in 1 mL
GLYCERIN (UNII: PDC6A3C0OX) (GLYCERIN - UNII:PDC6A3C0OX)	GLYCERIN	10 mg in 1 mL
POLYSORBATE 80 (UNII: 6OZP39ZG8H) (POLYSORBATE 80 - UNII:6OZP39ZG8H)	POLYSORBATE 80	5 mg in 1 mL

Ingredient Name	Strength
Inactive Ingredients
BORIC ACID (UNII: R57ZHV85D4)
BUTYLATED HYDROXYTOLUENE (UNII: 1P9D0Z171K)
CARBOMER COPOLYMER TYPE A (ALLYL PENTAERYTHRITOL CROSSLINKED) (UNII: 71DD5V995L)
CASTOR OIL (UNII: D5340Y2I9G)
ERYTHRITOL (UNII: RA96B954X6)
LINSEED OIL (UNII: 84XB4DV00W)
LEVOCARNITINE (UNII: 0G389FZZ9M)
POLYOXYL 40 STEARATE (UNII: 13A4J4NH9I)
WATER (UNII: 059QF0KO0R)
TREHALOSE (UNII: B8WCK70T7I)

Ingredient Kind	Ingredient Name	Quantity
Other Ingredients
May contain	SODIUM HYDROXIDE (UNII: 55X04QC32I)
May contain	HYDROCHLORIC ACID (UNII: QTT17582CB)

#	Item Code	Package Description	Marketing Start Date
Packaging
1	NDC:0023-7151-60	60 in 1 BOX	06/15/2021
1		0.4 mL in 1 VIAL, SINGLE-USE; Type 0: Not a Combination Product

Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
Marketing Information
OTC Monograph Drug	M018	06/15/2021

REFRESH OPTIVE MEGA-3
carboxymethylcellulose sodium, glycerin and polysorbate 80 solution/ drops

Product Information
Product Type	HUMAN OTC DRUG	Item Code (Source)	NDC:0023-5773
Route of Administration	OPHTHALMIC

Ingredient Name	Basis of Strength	Strength
Active Ingredient/Active Moiety
CARBOXYMETHYLCELLULOSE SODIUM (UNII: K679OBS311) (CARBOXYMETHYLCELLULOSE - UNII:05JZI7B19X)	CARBOXYMETHYLCELLULOSE SODIUM	5 mg in 1 mL
GLYCERIN (UNII: PDC6A3C0OX) (GLYCERIN - UNII:PDC6A3C0OX)	GLYCERIN	10 mg in 1 mL
POLYSORBATE 80 (UNII: 6OZP39ZG8H) (POLYSORBATE 80 - UNII:6OZP39ZG8H)	POLYSORBATE 80	5 mg in 1 mL

Ingredient Name	Strength
Inactive Ingredients
BORIC ACID (UNII: R57ZHV85D4)
BUTYLATED HYDROXYTOLUENE (UNII: 1P9D0Z171K)
CARBOMER COPOLYMER TYPE A (ALLYL PENTAERYTHRITOL CROSSLINKED) (UNII: 71DD5V995L)
CASTOR OIL (UNII: D5340Y2I9G)
ERYTHRITOL (UNII: RA96B954X6)
LINSEED OIL (UNII: 84XB4DV00W)
LEVOCARNITINE (UNII: 0G389FZZ9M)
POLYOXYL 40 STEARATE (UNII: 13A4J4NH9I)
WATER (UNII: 059QF0KO0R)
TREHALOSE (UNII: B8WCK70T7I)

Ingredient Kind	Ingredient Name	Quantity
Other Ingredients
May contain	SODIUM HYDROXIDE (UNII: 55X04QC32I)
May contain	HYDROCHLORIC ACID (UNII: QTT17582CB)

#	Item Code	Package Description	Marketing Start Date
Packaging
1	NDC:0023-5773-05	5 in 1 BOX	05/30/2017
1		0.4 mL in 1 VIAL, SINGLE-USE; Type 0: Not a Combination Product
2	NDC:0023-5773-30	30 in 1 BOX	05/30/2017
2		0.4 mL in 1 VIAL, SINGLE-USE; Type 0: Not a Combination Product

Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
Marketing Information
OTC Monograph Drug	M018	05/30/2017

Labeler - Allergan, Inc. (144796497)

REFRESH Optive Mega-3® (Preservative-free) Drug Facts

Active ingredients

Purpose

Uses

Warnings

Stop use and ask a doctor if

Keep out of reach of children.

Directions

Other information

Inactive ingredients

Questions or comments?

PRINCIPAL DISPLAY PANEL

PRINCIPAL DISPLAY PANEL

REFRESH Optive Mega-3® (Preservative-free)
Drug Facts