CARBON DIOXIDE - carbon dioxide gas 
Messer Merchant Production LLC

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Carbon Dioxide Refrigerated Liquid USP

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

CO2 USP CoA

BULK CARBON DIOXIDE USP CERTIFICATE OF ANALYSIS

This is to certify that the carbon dioxide produced at ______________________ on ______________________ meets the United States Pharmacopeia (USP) specifications, the requirements of Federal Specifications BB-C-101 Grade A and QVL E of CGA G6.2. This product was manufactured at a facility registered with the Federal Food and Drug Administration and is approved for prescription drug use. This product is not guaranteed to meet any other specification or intended for pesticide use.


Furthermore, batch number ______________________ and lot number ______________________, which was loaded on ______________________and filled at ______________________, comprises this shipment and was analyzed as shown below.


Analytical results are generated using USP monograph or validated equivalent methods.

RequirementTest MethodLimit of DetectionSpecification LimitAnalysis Results
Carbon Dioxide Assay (CO2)Zahm Nagel99.00%≥ 99.0%
Nitrogen Oxides (NOx)Detector Tube0.5 ppm2.5 ppm each
Ammonia (NH3)Detector Tube0.25 ppm25 ppm
Total SulfurAnalyzer10 ppb1000 ppb
Carbon Monoxide (CO)Detector Tube0.5 ppm10 ppm
Moisture (H2O)Analyzer0.5 ppm200 ppm or -33°F Dew Point

Note:
1) Positive Carbon Dioxide Identification is achieved when the Assay results demonstrate meeting the specification.
2) The limit of detection (LOD) for each test method is the threshold value for results to be reported with certainty in the accuracy of results. A test result outside the detection limit for the test method will be reported as ND.
3) ND=None Detected
4)ppm= parts per million by volume, ppb=parts per billion by volume, 1ppm=1,000 ppb
5) H2S, SO2, and other sulfur species are included in the total sulfur amount

Product analyzed using Messer Premier Guard Analysis suite


Analyst____________________________________________  Date: __________________________________



Reviewed and released by:____________________________  Date: __________________________________



_______________________________________________________________________

March 2019
CO2-22-06-RNA-Medical Gas USP Procedures
Page 1 of 1
Retention Period - 3 years

CARBON DIOXIDE  
carbon dioxide gas
Product Information
Product TypeHUMAN PRESCRIPTION DRUGItem Code (Source)NDC:45149-014
Route of AdministrationRESPIRATORY (INHALATION)
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Carbon Dioxide (UNII: 142M471B3J) (Carbon Dioxide - UNII:142M471B3J) Carbon Dioxide990 mL  in 1 L
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:45149-014-0118770 L in 1 TANK; Type 0: Not a Combination Product01/01/1965
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
NDANDA20581501/01/1965
Labeler - Messer Merchant Production LLC (809567303)
Registrant - Messer Merchant Production LLC (831800201)
Establishment
NameAddressID/FEIBusiness Operations
Messer Merchant Production LLC831800201manufacture(45149-014) , api manufacture(45149-014)

Revised: 10/2021
Document Id: 8fb06071-31b2-4b50-8869-20edb7ad9fb0
Set id: c1cba94b-7550-a95e-13ab-3c09aedde81a
Version: 12
Effective Time: 20211002
 
Messer Merchant Production LLC