CLOSYS SILVER SENSITIVE MOUTH RINSE FLUORIDE RINSE- sodium fluoride rinse 
Rowpar Pharmaceuticals, Inc.

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ClōSYS® Silver® Anticavity Fluoride Rinse

Drug Facts

Active ingredient

Sodium fluoride 0.02% (0.01% w/v fluoride ion)

Purpose

Anticavity

Uses

▪ Aids in the prevention of dental cavities

Warnings

Keep out of reach of children under 6 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away.

Directions

Adults and children 6 years of age and older

Children under 6 years

Other Information

Inactive ingredients

water, Cloralstan® (stabilized chlorine dioxide), trisodium phosphate, citric acid, peppermint flavor, sucralose

Questions or comments?
Call 1-800-643-3337

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

ClōSYS®
SILVER®


Anticavity Fluoride Mouth Rinse

HEALTHY TEETH

SENSITIVE MOUTH RINSE

WITH FLUORIDE
HELPS REBUILD WEAKENED TOOTH
ENAMEL & REVERSE EARLY TOOTH DECAY

Protects Against Cavities

Freshens Breath

Non Burning, Alcohol Free

Gentle pH Balanced

Gentle Mint

32 fl oz (946 mL)                                        52532-32



Distributed by:
Rowpar Pharmaceuticals, Inc.
Bridgewater, NJ 08807
1 (800) 643-3337 closys.com

This bottle is recyclable. Please
support recycling in your community         52532-33

Label

Non-Burning, Non-Irritating Formula

A CLEANER MOUTH
A HEALTHIER YOU®

ClōSYS®
SILVER®

Anticavity Fluoride Mouth Rinse

HEALTHY
TEETH

SENSITIVE
MOUTH RINCE

WITH FLUORIDE

HELPS REBUILD WEAKENED TOOTH
ENAMEL & REVERSE 
EARLY TOOTH DECAY

Protects Against Cavities

Freshens Breath

Non Burning, Alcohol Free

Gentle pH Balanced

Gentle Mint

32 fl oz (946 mL)

A CLEANER MOUTH
A HEALTHIER YOU®

ClōSYS®
SILVER®

Serious Science for Sensitive Mouths

How does CloSYS® Silver
with Flouride Work?

CloSYS® Silver Healthy Teeth Mouth Rinse contains fluoride to help protect against cavities. With regular use, it helps rebuild weakened tooth enamel, reverse early tooth decay, and strengthen teeth to improve their appearance. The patented dual action formula contains Cloralstan® which kills bad breath bacteria and neutralizes sulfur mouth odor molecules for long lasting fresh breath. CloSYS® Silver Healthy Teeth Mouth Rinse does not contain alcohol, sulfates, triclosan, and other ingredients that can burn or irritate the mouth so you can rinse longer to get great results!

HEALTHY Mouth = HEALTHY Body

Gentlest.
Oral Care.
Ever.®

A CLEANER MOUTH
A HEALTHIER YOU®

ClōSYS®
SILVER®

Serious Science for Sensitive Mouths

Our Story

Founder of CloSYS® & Periodontist Dr. Perry Ratcliff had a bold belief that there had to be a better/gentler way to help with oral care. Dr. Ratcliff didn't agree with the common myth ‘If it hurts, it must be good for you’

CloSYS® took a different approach—keep it gentle, yet effective, and people will use it long enough to make a difference in their oral health. After discovering that his first patented formula was not only extremely gentle but incredibly effective, he gathered a small group of dental professionals and business leaders to start their journey toward what is today CloSYS® Oral Care.

What Makes CloSYS®
Product Different?

Simply put, CloSYS® is the Gentlest. Oral Care. Ever.® All CloSYS® formulas are highly effective and extremely gentle so they are not harsh or irritating to sensitive mouths. And because it’s so gentle, it means you can swish it in your mouth longer without having to spit it out early and risk not getting the full benefit of the rinse.

CloSYS® products are free of alcohol, sulfates, triclosan, and other harsh ingredients that can burn or irritate sensitive mouths.

Distributed by:
Rowpar Pharmaceuticals, Inc.
Bridgewater, NJ 08807
1 (800) 643-3337 closys.com

This bottle is recyclable. Please
support recycling in your community 

55032-42

carton
CLOSYS SILVER SENSITIVE MOUTH RINSE  FLUORIDE RINSE
sodium fluoride rinse
Product Information
Product TypeHUMAN OTC DRUGItem Code (Source)NDC:58578-0517
Route of AdministrationORAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
SODIUM FLUORIDE (UNII: 8ZYQ1474W7) (FLUORIDE ION - UNII:Q80VPU408O) FLUORIDE ION0.02 g  in 100 mL
Inactive Ingredients
Ingredient NameStrength
WATER (UNII: 059QF0KO0R)  
CHLORINE DIOXIDE (UNII: 8061YMS4RM)  
SODIUM PHOSPHATE, TRIBASIC, DODECAHYDRATE (UNII: B70850QPHR)  
ANHYDROUS CITRIC ACID (UNII: XF417D3PSL)  
PEPPERMINT (UNII: V95R5KMY2B)  
SUCRALOSE (UNII: 96K6UQ3ZD4)  
Product Characteristics
Color    Score    
ShapeSize
FlavorPEPPERMINTImprint Code
Contains    
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:58578-0517-11 in 1 BOX01/01/2024
1473 mL in 1 BOTTLE; Type 0: Not a Combination Product
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC Monograph DrugM02101/01/2023
Labeler - Rowpar Pharmaceuticals, Inc. (783704661)

Revised: 12/2023
Document Id: f8d73290-2f64-490f-a603-efc11de6ccca
Set id: 98a8cee8-9f3c-4a4a-89f8-72e1f1b06796
Version: 2
Effective Time: 20231226
 
Rowpar Pharmaceuticals, Inc.