UP AND UP DAYTIME SEVERE COLD NIGHTTIME COLD AND FLU- acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl, diphenhydramine hcl 
Target Corporation

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

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Target Corporation Daytime Severe Cold Nighttime Cold and Flu Drug Facts

Active ingredients (in each caplet) - DAY TIME Severe Cold

Acetaminophen 325 mg

Dextromethorphan HBr 10 mg

Guaifenesin 200 mg

Phenylephrine HCl 5 mg

Active ingredients (in each caplet) – NIGHT TIME Cold & Flu

Acetaminophen 325 mg

Diphenhydramine HCl 25 mg

Phenylephrine HCl 5 mg

Purposes - DAY TIME Severe Cold

Pain reliever/fever reducer

Cough suppressant

Expectorant

Nasal decongestant

Purposes - NIGHT TIME Cold & Flu

Pain reliever/fever reducer

Antihistamine

Nasal decongestant

Uses

temporarily relieves these common cold and flu symptoms:
nasal congestion
cough (DAY TIME Severe Cold only)
minor aches and pains
headache
sore throat
runny nose and sneezing (NIGHT TIME Cold & Flu only)
helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive (DAY TIME Severe Cold only)
temporarily reduces fever

Warnings

Liver warning: These products contain acetaminophen. Severe liver damage may occur if you take

more than 4,000 mg of acetaminophen in 24 hours
with other drugs containing acetaminophen
3 or more alcoholic drinks every day while using these products

Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:

skin reddening
blisters
rash

If a skin reaction occurs, stop use and seek medical help right away.

Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

Do not use

with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
with any other product containing diphenhydramine, even one used on skin (NIGHT TIME Cold & Flu only)
if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking these products.
if you have ever had an allergic reaction to these products or any of their ingredients

Ask a doctor before use if you have

liver disease
heart disease
high blood pressure
thyroid disease
diabetes
trouble urinating due to an enlarged prostate gland
glaucoma (NIGHT TIME Cold & Flu only)
a breathing problem such as emphysema or chronic bronchitis (NIGHT TIME Cold & Flu only)
persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema (DAY TIME Severe Cold only)
cough that occurs with too much phlegm (mucus) (DAY TIME Severe Cold only)

Ask a doctor or pharmacist before use if you are

taking the blood thinning drug warfarin
taking sedatives or tranquilizers (NIGHT TIME Cold & Flu only)

When using these products

do not use more than directed
excitability may occur, especially in children (NIGHT TIME Cold & Flu only)
marked drowsiness may occur (NIGHT TIME Cold & Flu only)
alcohol, sedatives, and tranquilizers may increase drowsiness (NIGHT TIME Cold & Flu only)
avoid alcoholic drinks (NIGHT TIME Cold & Flu only)
be careful when driving a motor vehicle or operating machinery (NIGHT TIME Cold & Flu only)

Stop use and ask a doctor if

nervousness, dizziness, or sleeplessness occur
pain, nasal congestion or cough gets worse or lasts more than 7 days
fever gets worse or lasts more than 3 days
redness or swelling is present
new symptoms occur
cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. (DAY TIME Severe Cold only)

If pregnant or breast-feeding,

ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

do not take more than directed (see Overdose warning)
do not take more than 10 caplets in any 24-hour period
adults and children 12 years of age and older: take 2 caplets every 4 hours
children under 12 years of age: do not use

Other information

each caplet contains: sodium 4 mg (DAY TIME Severe Cold only)
store at 20-25°C (68-77°F)

Inactive ingredients (DAY TIME Severe Cold)

croscarmellose sodium, crospovidone, FD&C blue #2 aluminum lake, FD&C red #40 aluminum lake, maltodextrin, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, pregelatinized starch, silicon dioxide, stearic acid, talc, titanium dioxide

Inactive ingredients (NIGHT TIME Cold & Flu)

crospovidone, FD&C blue #1 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, pregelatinized starch, silicon dioxide, stearic acid, talc, titanium dioxide

Questions?

Call 1-888-547-7400

Principal Display Panel

Compare to active ingredients in Mucinex® Fast-Max® Day Time Severe Cold

see new warnings

maximum strength

daytime severe cold

acetaminophen (pain reliever/fever reducer)

dextromethorphan HBr (cough suppressant)

guaifenesin (expectorant)

phenylephrine HCl (nasal decongestant)

relieves headache, fever and sore throat

relieves nasal and chest congestion

controls cough

thins and loosens mucus

ACTUAL SIZE

AGES 12+ YEARS

20 CAPLETS

Compare to active ingredients in Mucinex® Fast-Max® Night Time Cold & Flu

see new warnings

maximum strength

nighttime cold and flu

acetaminophen (pain reliever/fever reducer)

diphenhydramine HCl (antihistamine)

phenylephrine HCL (nasal decongestant)

relieves headache, fever and sore throat

relieves nasal congestion

relieves sneezing and runny nose

ACTUAL SIZE

AGES 12+ YEARS

10 CAPLETS

Up & Up daytime severe cold nighttime cold & flu image 1
Up & Up daytime severe cold nighttime cold and flu image 2
Up & Up daytime severe cold nighttime cold and flu image 3
UP AND UP DAYTIME SEVERE COLD NIGHTTIME COLD AND FLU 
acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl, diphenhydramine hcl kit
Product Information
Product TypeHUMAN OTC DRUGItem Code (Source)NDC:11673-837
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:11673-837-811 in 1 KIT; Type 0: Not a Combination Product03/25/2015
Quantity of Parts
Part #Package QuantityTotal Product Quantity
Part 110 BLISTER PACK 20 
Part 25 BLISTER PACK 10 
Part 1 of 2
UP AND UP DAYTIME SEVERE COLD 
acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl tablet, film coated
Product Information
Route of AdministrationORAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
ACETAMINOPHEN (UNII: 362O9ITL9D) (ACETAMINOPHEN - UNII:362O9ITL9D) ACETAMINOPHEN325 mg
DEXTROMETHORPHAN HYDROBROMIDE (UNII: 9D2RTI9KYH) (DEXTROMETHORPHAN - UNII:7355X3ROTS) DEXTROMETHORPHAN HYDROBROMIDE10 mg
GUAIFENESIN (UNII: 495W7451VQ) (GUAIFENESIN - UNII:495W7451VQ) GUAIFENESIN200 mg
PHENYLEPHRINE HYDROCHLORIDE (UNII: 04JA59TNSJ) (PHENYLEPHRINE - UNII:1WS297W6MV) PHENYLEPHRINE HYDROCHLORIDE5 mg
Inactive Ingredients
Ingredient NameStrength
CROSCARMELLOSE SODIUM (UNII: M28OL1HH48)  
CROSPOVIDONE (15 MPA.S AT 5%) (UNII: 68401960MK)  
MALTODEXTRIN (UNII: 7CVR7L4A2D)  
MICROCRYSTALLINE CELLULOSE (UNII: OP1R32D61U)  
POLYETHYLENE GLYCOL (UNII: 3WJQ0SDW1A)  
POLYVINYL ALCOHOL (UNII: 532B59J990)  
POVIDONE (UNII: FZ989GH94E)  
SILICON DIOXIDE (UNII: ETJ7Z6XBU4)  
STEARIC ACID (UNII: 4ELV7Z65AP)  
TALC (UNII: 7SEV7J4R1U)  
TITANIUM DIOXIDE (UNII: 15FIX9V2JP)  
Product Characteristics
ColorREDScoreno score
ShapeCAPSULESize20mm
FlavorImprint Code L922
Contains    
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
110 in 1 PACKAGE
12 in 1 BLISTER PACK; Type 0: Not a Combination Product
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC monograph finalpart34103/16/2015
Part 2 of 2
UP AND UP NIGHTTIME COLD AND FLU 
acetaminophen, diphenhydramine hcl, phenylephrine hcl tablet, film coated
Product Information
Route of AdministrationORAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
ACETAMINOPHEN (UNII: 362O9ITL9D) (ACETAMINOPHEN - UNII:362O9ITL9D) ACETAMINOPHEN325 mg
DIPHENHYDRAMINE HYDROCHLORIDE (UNII: TC2D6JAD40) (DIPHENHYDRAMINE - UNII:8GTS82S83M) DIPHENHYDRAMINE HYDROCHLORIDE25 mg
PHENYLEPHRINE HYDROCHLORIDE (UNII: 04JA59TNSJ) (PHENYLEPHRINE - UNII:1WS297W6MV) PHENYLEPHRINE HYDROCHLORIDE5 mg
Inactive Ingredients
Ingredient NameStrength
CROSPOVIDONE (15 MPA.S AT 5%) (UNII: 68401960MK)  
MAGNESIUM STEARATE (UNII: 70097M6I30)  
MICROCRYSTALLINE CELLULOSE (UNII: OP1R32D61U)  
POLYETHYLENE GLYCOL (UNII: 3WJQ0SDW1A)  
POLYVINYL ALCOHOL (UNII: 532B59J990)  
POVIDONE (UNII: FZ989GH94E)  
SILICON DIOXIDE (UNII: ETJ7Z6XBU4)  
STEARIC ACID (UNII: 4ELV7Z65AP)  
TALC (UNII: 7SEV7J4R1U)  
TITANIUM DIOXIDE (UNII: 15FIX9V2JP)  
Product Characteristics
ColorBLUEScoreno score
ShapeCAPSULESize16mm
FlavorImprint Code
Contains    
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
15 in 1 PACKAGE
12 in 1 BLISTER PACK; Type 0: Not a Combination Product
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC monograph finalpart341
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC monograph finalpart34103/25/2015
Labeler - Target Corporation (006961700)

Revised: 12/2019
Document Id: 98aa0a3f-d3da-49bc-8a16-b323920dd00e
Set id: 8d39719b-6820-4a85-a42d-f683f3efdc09
Version: 4
Effective Time: 20191213
 
Target Corporation