Active ingredients

Carboxymethylcellulose sodium 0.5%

Glycerin 0.9%

Purpose

Eye lubricant

Uses

For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun.
May be used as a protectant against further irritation.

Warnings

For external use only.
To avoid contamination, do not touch tip of container to any surface. Do not reuse. Once opened, discard.
Do not touch unit-dose tip to eye.
If solution changes color, do not use.

Stop use and ask a doctor if

you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.

Keep out of reach of children.

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

To open, TWIST AND PULL TAB TO REMOVE. Instill 1 or 2 drops in the affected eye(s) as needed and discard container. *Follow your eye doctor’s instructions if you are using this product after an eye surgery (e.g., LASIK) to relieve eye dryness and discomfort.

Other information

Use only if single-use container is intact.
Use before expiration date marked on container.
Store at 59°-77°F (15°-25°C).
RETAIN THIS CARTON FOR FUTURE REFERENCE.

Inactive ingredients

Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; and sodium citrate dihydrate.

Questions or comments?

1.800.678.1605

refreshbrand.com

v1.0DFL3416

PRINCIPAL DISPLAY PANEL

NDC 0023-3416-30
Preservative-free
Refresh
Optive®
Lubricant Eye Drops
LONG-LASTING HYDRATION
Lubricating and hydrating formula
penetrates the surface to relieve dryness.
Also recommended for LASIK dryness.*
30 Vials 0.01 fl oz (0.4 mL) each Sterile

PRINCIPAL DISPLAY PANEL
NDC 0023-3416-30
Preservative-free
Refresh
Optive®
Lubricant Eye Drops
LONG-LASTING HYDRATION
Lubricating and hydrating formula
penetrates the surface to relieve dryness.
Also recommended for LASIK dryness.*
30 Vials 0.01 fl oz (0.4 mL) each Sterile

REFRESH OPTIVE
carboxymethylcellulose sodium, glycerin solution/ drops

Product Information
Product Type	HUMAN OTC DRUG	Item Code (Source)	NDC:0023-3416
Route of Administration	OPHTHALMIC

Ingredient Name	Basis of Strength	Strength
Active Ingredient/Active Moiety
Carboxymethylcellulose Sodium (UNII: K679OBS311) (Carboxymethylcellulose - UNII:05JZI7B19X)	Carboxymethylcellulose Sodium	5 mg in 1 mL
Glycerin (UNII: PDC6A3C0OX) (Glycerin - UNII:PDC6A3C0OX)	Glycerin	9 mg in 1 mL

Ingredient Name	Strength
Inactive Ingredients
Boric Acid (UNII: R57ZHV85D4)
Calcium Chloride (UNII: M4I0D6VV5M)
Erythritol (UNII: RA96B954X6)
Levocarnitine (UNII: 0G389FZZ9M)
Magnesium Chloride (UNII: 02F3473H9O)
potassium chloride (UNII: 660YQ98I10)
water (UNII: 059QF0KO0R)
sodium borate (UNII: 91MBZ8H3QO)
trisodium citrate dihydrate (UNII: B22547B95K)

#	Item Code	Package Description	Marketing Start Date
Packaging
1	NDC:0023-3416-05	5 in 1 CARTON	08/22/2008
1		0.4 mL in 1 VIAL, SINGLE-USE; Type 0: Not a Combination Product
2	NDC:0023-3416-30	30 in 1 CARTON	08/22/2008
2		0.4 mL in 1 VIAL, SINGLE-USE; Type 0: Not a Combination Product
3	NDC:0023-3416-60	60 in 1 CARTON	08/22/2008
3		0.4 mL in 1 VIAL, SINGLE-USE; Type 0: Not a Combination Product

Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
Marketing Information
OTC Monograph Drug	M018	08/22/2008

Labeler - Allergan, Inc. (144796497)

REFRESH OPTIVE® (Preservative-Free) Unit Dose Drug Facts