REFRESH OPTIVE- carboxymethylcellulose sodium, glycerin solution/ drops 
Allergan, Inc.

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

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REFRESH OPTIVE®

Drug Facts

Active ingredients

Carboxymethylcellulose sodium 0.5%

Glycerin 0.9%

Purpose

Eye lubricant

Eye lubricant

Uses

Warnings

Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

To open, TWIST AND PULL TAB TO REMOVE. Instill 1 or 2 drops in the affected eye(s) as needed and discard container.

*lf used for post-operative (e.g., LASIK) dryness and discomfort, follow your eye doctor's instructions.

Other information

Inactive ingredients

Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; and sodium citrate dihydrate.

Questions or comments?

1.800.678.1605

refreshbrand.com

NDC 0023-3416-30

Preservative-free

Refresh
Optive
®
Lubricant Eye Drops

LONG-LASTING HYDRATION

Lubricating and hydrating formula
penetrates the surface to relieve dryness.
Also recommended for LASIK dryness.*

30 Single-Use Containers
0.01 fl oz (0.4 mL) each Sterile

Carton
REFRESH OPTIVE 
carboxymethylcellulose sodium, glycerin solution/ drops
Product Information
Product TypeHUMAN OTC DRUGItem Code (Source)NDC:0023-3416
Route of AdministrationOPHTHALMIC
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Carboxymethylcellulose Sodium (UNII: K679OBS311) (Carboxymethylcellulose - UNII:05JZI7B19X) Carboxymethylcellulose Sodium5 mg  in 1 mL
Glycerin (UNII: PDC6A3C0OX) (Glycerin - UNII:PDC6A3C0OX) Glycerin9 mg  in 1 mL
Inactive Ingredients
Ingredient NameStrength
Boric Acid (UNII: R57ZHV85D4)  
Calcium Chloride (UNII: M4I0D6VV5M)  
Erythritol (UNII: RA96B954X6)  
Levocarnitine (UNII: 0G389FZZ9M)  
Magnesium Chloride (UNII: 02F3473H9O)  
potassium chloride (UNII: 660YQ98I10)  
water (UNII: 059QF0KO0R)  
sodium borate (UNII: 91MBZ8H3QO)  
trisodium citrate dihydrate (UNII: B22547B95K)  
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:0023-3416-055 in 1 CARTON08/22/2008
10.4 mL in 1 VIAL, SINGLE-USE; Type 0: Not a Combination Product
2NDC:0023-3416-3030 in 1 CARTON08/22/2008
20.4 mL in 1 VIAL, SINGLE-USE; Type 0: Not a Combination Product
3NDC:0023-3416-6060 in 1 CARTON08/22/2008
30.4 mL in 1 VIAL, SINGLE-USE; Type 0: Not a Combination Product
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC MONOGRAPH FINALpart34908/22/2008
Labeler - Allergan, Inc. (144796497)

Revised: 7/2014
Document Id: 9e373826-4f0b-4608-9cb5-e42bbe822ac4
Set id: 37e99aa8-02d6-4efb-a862-90bc7fcd5ca5
Version: 6
Effective Time: 20140715
 
Allergan, Inc.