HEAD AND SHOULDERS 2IN1 ADVANCED SCALP CARE 2IN1- pyrithione zinc lotion/shampoo 
The Procter & Gamble Manufacturing Company

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Head and Shoulders ® 2in1 Advanced Complete Scalp Care

Drug Facts

Active ingredient

Pyrithione zinc 1%

Purpose

Anti-dandruff

Uses

helps prevent recurrence of flaking and itching associated with dandruff.

Warnings

For external use only.

When using this product

  • avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.

Stop use and ask a doctor if

  • condition worsens or does not improve after regular use of this product as directed.

Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

Inactive ingredients

Water, sodium laureth sulfate, sodium lauryl sulfate, cocamidopropyl betaine, sodium xylenesulfonate, zinc carbonate, glycol distearate, fragrance, sodium chloride, dimethiconol, dimethicone, sodium benzoate, guar hydroxypropyltrimonium chloride, tea-dodecylbenzenesulfonate, trideceth-10, magnesium carbonate hydroxide, aloe barbadensis leaf juice, tocopheryl acetate, niacinamide, cocos nucifera (coconut) fruit juice, benzyl alcohol, methylchloroisothiazolinone, methylisothiazolinone

Questions (or comments)?

1-800-723-9569

Dist. by PROCTER & GAMBLE,
CINCINNATI, OH 45202

PRINCIPAL DISPLAY PANEL - 1.18 L Bottle Label

head &

shoulders ®

pyrithione zinc dandruff

shampoo + conditioner

2in1

ADVANCED
SCALP CARE


WITH ALOE VERA, COCONUT WATER &

VITAMINS E, B3


40 FL OZ (1.18 L)

HS

HEAD AND SHOULDERS 2IN1 ADVANCED SCALP CARE 2IN1 
pyrithione zinc lotion/shampoo
Product Information
Product TypeHUMAN OTC DRUGItem Code (Source)NDC:84126-022
Route of AdministrationTOPICAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
PYRITHIONE ZINC (UNII: R953O2RHZ5) (PYRITHIONE ZINC - UNII:R953O2RHZ5) PYRITHIONE ZINC1 g  in 100 mL
Inactive Ingredients
Ingredient NameStrength
SODIUM LAURETH-3 SULFATE (UNII: BPV390UAP0)  
SODIUM LAURYL SULFATE (UNII: 368GB5141J)  
DIMETHICONE (UNII: 92RU3N3Y1O)  
ZINC CARBONATE (UNII: EQR32Y7H0M)  
GLYCOL DISTEARATE (UNII: 13W7MDN21W)  
SODIUM XYLENESULFONATE (UNII: G4LZF950UR)  
SODIUM CHLORIDE (UNII: 451W47IQ8X)  
SODIUM BENZOATE (UNII: OJ245FE5EU)  
MAGNESIUM CARBONATE HYDROXIDE (UNII: YQO029V1L4)  
COCAMIDOPROPYL BETAINE (UNII: 5OCF3O11KX)  
TRIETHANOLAMINE DODECYLBENZENESULFONATE (UNII: 8HM7ZD48HN)  
METHYLCHLOROISOTHIAZOLINONE (UNII: DEL7T5QRPN)  
ALPHA-TOCOPHEROL ACETATE (UNII: 9E8X80D2L0)  
COCONUT JUICE (UNII: AMN6S4M09G)  
NIACINAMIDE (UNII: 25X51I8RD4)  
BENZYL ALCOHOL (UNII: LKG8494WBH)  
METHYLISOTHIAZOLINONE (UNII: 229D0E1QFA)  
TRIDECETH-10 (UNII: G624N6MSBA)  
DIMETHICONOL (50000 CST) (UNII: R2285D73YT)  
ALOE VERA LEAF (UNII: ZY81Z83H0X)  
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE (1.7 SUBSTITUENTS PER SACCHARIDE) (UNII: B16G315W7A)  
WATER (UNII: 059QF0KO0R)  
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:84126-022-111180 mL in 1 BOTTLE, PUMP; Type 0: Not a Combination Product02/20/2024
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC Monograph DrugM03202/20/2024
Labeler - The Procter & Gamble Manufacturing Company (004238200)

Revised: 12/2025
Document Id: 474847c4-a0d6-5379-e063-6394a90abc8e
Set id: 20c2b492-2487-750b-e063-6294a90a630a
Version: 2
Effective Time: 20251231
 
The Procter & Gamble Manufacturing Company