DIFFERIN DAILY DEEP CLEANSER WITH BPO - benzoyl peroxide solution 
Galderma Laboratories, L.P.

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.


Drug Facts

Differin Daily Deep Cleanser with Benzoyl Peroxide
Galderma Laboratories, L.P.

Active Ingredients

 Benzoyl Peroxide 5% 


Acne treatment


For the treatment of acne                 


For external use only.

When using this product
■ skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. ■ avoid unnecessary sun exposure and use a sunscreen ■ avoid contact with the eyes, lips, and mouth ■ avoid contact with hair and dyed fabrics, which may be bleached by this product ■ skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration.

Do not use if you
■ Have very sensitive skin
■ Are sensitive to benzoyl peroxide

Stop use and ask a doctor if
■ Irritation becomes severe

Keep out of reach of children.
If swallowed, get medical help or contact a Poison Control Center right away.


■ Wet face. Gently massage all over face for about 20 – 30 seconds, avoiding the eye area. Rinse thoroughly and pat dry. ■ Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor. ■ If bothersome dryness or peeling occurs, reduce application to once a day or every other day. ■ If going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor.

Inactive Ingredients

Carbomer, Glycerin, Lauryl Methacrylate/Glycol Dimethacrylate Crosspolymer, Sodium C14-16 Olefin Sulfonate, Sodium Hydroxide, Water

Questions or comments?


Distributed by:

Galderma Laboratories, L.P.

Fort Worth, TX 76177

All trademarks are the property of their respective owners

Made in Canada


Principle Display Panel

P53661-3 Diff BPO Cleanser carton image




Daily Deep

Sensitive Skin

∙ Oil-absorbing

∙ Moisturizer-releasing

4 FL OZ (118 mL)

benzoyl peroxide solution
Product Information
Product TypeHUMAN OTC DRUGItem Code (Source)NDC:0299-4606
Route of AdministrationTOPICAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Benzoyl Peroxide (UNII: W9WZN9A0GM) (Benzoyl Peroxide - UNII:W9WZN9A0GM) Benzoyl Peroxide5 g  in 100 mL
Inactive Ingredients
Ingredient NameStrength
Carboxypolymethylene (UNII: 0A5MM307FC)  
Lauryl Methacrylate/glycol Dimethacrylate Crosspolymer (UNII: EX0F4CZ66H)  
Sodium C14-16 Olefin Sulfonate (UNII: O9W3D3YF5U)  
Sodium Hydroxide (UNII: 55X04QC32I)  
Water (UNII: 059QF0KO0R)  
Glycerin (UNII: PDC6A3C0OX)  
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:0299-4606-001 in 1 BOX11/01/2017
1118 mL in 1 TUBE; Type 0: Not a Combination Product
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC monograph finalpart333D11/01/2017
Labeler - Galderma Laboratories, L.P. (047350186)
NameAddressID/FEIBusiness Operations
G Production Inc.251676961manufacture(0299-4606)

Revised: 8/2020
Document Id: e52fa770-1187-4443-a0a1-7b06461d6762
Set id: 192b231b-51f1-457c-9a82-ef75671c0d34
Version: 2
Effective Time: 20200831
Galderma Laboratories, L.P.