CLEAR DIFFERENCE ADVANCED BLEMISH SERUM- salicylic acid lotion 
ESTEE LAUDER INC

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

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CLEAR DIFFERENCE ADVANCED BLEMISH SERUM

Drug Facts

Active ingredient

Salicylic acid 0.50%

Purpose

Acne treatment

Use

For the treatment of acne.

Warnings

For external use only

When using this product using other topical acne drugs at the same time or right after use of this product may increase dryness or irritation of the skin. If this occurs, only one medication should be used unless directed by a doctor.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

  • cleanse skin thoroughly before applying
  • cover the entire affected area with one application daily
  • gradually increase to 2 times daily if needed or as directed by a doctor
  • if bothersome dryness or peeling occurs, reduce application to every other day
  • follow with your moisturizer

Inactive ingredients

water\aqua\eau • dimethicone • hamamelis virginiana (witch hazel) water • ppg-14 butyl ether • acetyl glucosamine • sucrose • isodecyl neopentanoate • steareth-21 • glycine • acrylamide/sodium acryloyldimethyltaurate copolymer • laminaria saccharina extract • caffeine • tocopheryl acetate • isohexadecane • steareth-2 • algae extract • sodium hyaluronate • polysorbate 80 • quaternium-22 • butylene glycol • sodium hydroxide • pentylene glycol • disodium edta • fragrance (parfum) • limonene • linalool • phenoxyethanol • benzalkonium chloride • green 5 (ci 61570) • yellow 5 (ci 19140) <iln40165>

PRINCIPAL DISPLAY PANEL - 50 ml Bottle Carton

ESTĒE LAUDER

Clear
Difference
Advanced
Blemish Serum

SALICYLIC ACID ACNE TREATMENT

1.7 FL. OZ. LIQ./50 ml e

Principal Display Panel - 50 ml Bottle Carton
CLEAR DIFFERENCE ADVANCED BLEMISH SERUM 
salicylic acid lotion
Product Information
Product TypeHUMAN OTC DRUGItem Code (Source)NDC:11559-041
Route of AdministrationTOPICAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
SALICYLIC ACID (UNII: O414PZ4LPZ) (SALICYLIC ACID - UNII:O414PZ4LPZ) SALICYLIC ACID0.0053 g  in 100 mL
Inactive Ingredients
Ingredient NameStrength
WATER (UNII: 059QF0KO0R)  
DIMETHICONE (UNII: 92RU3N3Y1O)  
HAMAMELIS VIRGINIANA TOP WATER (UNII: NT00Y05A2V)  
PPG-14 BUTYL ETHER (UNII: R199TJT95T)  
N-ACETYLGLUCOSAMINE (UNII: V956696549)  
SUCROSE (UNII: C151H8M554)  
ISODECYL NEOPENTANOATE (UNII: W60VYE24XC)  
STEARETH-21 (UNII: 53J3F32P58)  
GLYCINE (UNII: TE7660XO1C)  
SACCHARINA LATISSIMA (UNII: 68CMP2MB55)  
CAFFEINE (UNII: 3G6A5W338E)  
.ALPHA.-TOCOPHEROL ACETATE (UNII: 9E8X80D2L0)  
ISOHEXADECANE (UNII: 918X1OUF1E)  
STEARETH-2 (UNII: V56DFE46J5)  
HYALURONATE SODIUM (UNII: YSE9PPT4TH)  
POLYSORBATE 80 (UNII: 6OZP39ZG8H)  
QUATERNIUM-22 (UNII: MXO138JCBP)  
BUTYLENE GLYCOL (UNII: 3XUS85K0RA)  
SODIUM HYDROXIDE (UNII: 55X04QC32I)  
PENTYLENE GLYCOL (UNII: 50C1307PZG)  
EDETATE DISODIUM (UNII: 7FLD91C86K)  
LINALOOL, (+/-)- (UNII: D81QY6I88E)  
PHENOXYETHANOL (UNII: HIE492ZZ3T)  
BENZALKONIUM CHLORIDE (UNII: F5UM2KM3W7)  
D&C GREEN NO. 5 (UNII: 8J6RDU8L9X)  
FD&C YELLOW NO. 5 (UNII: I753WB2F1M)  
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:11559-041-011 in 1 CARTON04/01/2014
150 mL in 1 BOTTLE; Type 0: Not a Combination Product
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC MONOGRAPH FINALpart333D04/01/201411/12/2020
Labeler - ESTEE LAUDER INC (005914387)
Establishment
NameAddressID/FEIBusiness Operations
ESTEE LAUDER COMPANY, THE828534516RELABEL(11559-041) , REPACK(11559-041)
Establishment
NameAddressID/FEIBusiness Operations
Estee Lauder Cosmetics, Ltd.244669714MANUFACTURE(11559-041)
Establishment
NameAddressID/FEIBusiness Operations
ESTEE LAUDER COSMETICS, LTD.202952982MANUFACTURE(11559-041)
Establishment
NameAddressID/FEIBusiness Operations
Estee Lauder N.V.370151326MANUFACTURE(11559-041)
Establishment
NameAddressID/FEIBusiness Operations
LEN-RON MANUFACTURING DIVISION OF ARAMIS INC809771152MANUFACTURE(11559-041)
Establishment
NameAddressID/FEIBusiness Operations
NORTHTEC INC943871157RELABEL(11559-041) , REPACK(11559-041)
Establishment
NameAddressID/FEIBusiness Operations
PADC 1949264774RELABEL(11559-041) , REPACK(11559-041)
Establishment
NameAddressID/FEIBusiness Operations
WHITMAN LABORATORIES, LTD.216866277MANUFACTURE(11559-041)
Establishment
NameAddressID/FEIBusiness Operations
ESTEE LAUDER COSMETICS, LTD255175580MANUFACTURE(11559-041)

Revised: 11/2020
 
ESTEE LAUDER INC