Label: LA ROCHE POSAY LABORATOIRE DERMATOLOGIQUE EFFACLAR DUO PLUS M MULTI TARGET ACNE TREATMENT- salicylic acid liquid

  • NDC Code(s): 69625-926-01, 69625-926-02
  • Packager: COSMETIQUE ACTIVE PRODUCTION
  • Category: HUMAN OTC DRUG LABEL
  • DEA Schedule: None

Drug Label Information

Updated June 5, 2025

If you are a consumer or patient please visit this version.

  • Active ingredient

    Salicylic acid 0.5%

  • Purpose

    Acne treatment

  • Uses

    • clears acne blemishes
    • penetrates pores to control acne blemishes
    • helps prevent new acne blemishes from forming
  • Warnings

    For external use only

  • When using this product

    skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.

  • Keep out of reach of children.

    If swallowed, get medical help or contact a Poison Control Center right away.

  • Directions

    • clean the skin thoroughly before applying this product
    • cover the entire affected area with a thin layer one to three times daily
    • because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor
    • if bothersome dryness or peeling occurs, reduce application to once a day or every other day
    • if going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor.
  • Inactive ingredients

    water, glycerin, dimethicone, isocetyl stearate, niacinamide, isopropyl lauroyl sarcosinate, silica, ammonium polyacryloyldimethyl taurate, oryza sativa (rice) starch, punica granatum pericarp extract, potassium cetyl phosphate, sorbitan oleate, zinc PCA, glyceryl stearate SE, isohexadecane, sodium hydroxide, myristyl myristate, 2-oleamido-1,3-octadecanediol, mannose, poloxamer 338, propanediol, hydroxyethoxyphenyl butanone, capryloyl salicylic acid, caprylyl glycol, vitreoscilla ferment, citric acid, trisodium ethylenediamine disuccinate, maltodextrin, xanthan gum, pentylene glycol, polysorbate 80, acrylamide/sodium acryloyldimethyltaurate copolymer, piroctone olamine, fragrance

  • Questions or comments?

    1-888-LRP LABO

    1-888-577-5226

    Monday - Friday (9 a.m. - 5 p.m. EST)

  • PRINCIPAL DISPLAY PANEL

    image of a carton

  • INGREDIENTS AND APPEARANCE
    LA ROCHE POSAY LABORATOIRE DERMATOLOGIQUE EFFACLAR DUO PLUS M MULTI TARGET ACNE TREATMENT 
    salicylic acid liquid
    Product Information
    Product TypeHUMAN OTC DRUGItem Code (Source)NDC:69625-926
    Route of AdministrationTOPICAL
    Active Ingredient/Active Moiety
    Ingredient NameBasis of StrengthStrength
    SALICYLIC ACID (UNII: O414PZ4LPZ) (SALICYLIC ACID - UNII:O414PZ4LPZ) SALICYLIC ACID5 mg  in 1 mL
    Inactive Ingredients
    Ingredient NameStrength
    WATER (UNII: 059QF0KO0R)  
    GLYCERIN (UNII: PDC6A3C0OX)  
    DIMETHICONE (UNII: 92RU3N3Y1O)  
    ISOCETYL STEARATE (UNII: 3RJ7186O9W)  
    NIACINAMIDE (UNII: 25X51I8RD4)  
    ISOPROPYL LAUROYL SARCOSINATE (UNII: LYR06W430J)  
    SILICON DIOXIDE (UNII: ETJ7Z6XBU4)  
    AMMONIUM POLYACRYLOYLDIMETHYL TAURATE (UNII: F01RIY4371)  
    ORYZA SATIVA (RICE) STARCH (UNII: 4DGK8B7I3S)  
    POMEGRANATE FRUIT RIND (UNII: RS999V57DU)  
    POTASSIUM CETYL PHOSPHATE (UNII: 03KCY6P7UT)  
    SORBITAN OLEATE (UNII: 06XEA2VD56)  
    ZINC PCA (UNII: C32PQ86DH4)  
    GLYCERYL STEARATE SE (UNII: FCZ5MH785I)  
    ISOHEXADECANE (UNII: 918X1OUF1E)  
    SODIUM HYDROXIDE (UNII: 55X04QC32I)  
    MYRISTYL MYRISTATE (UNII: 4042ZC00DY)  
    2-OLEAMIDO-1,3-OCTADECANEDIOL (UNII: 30D478BUNR)  
    MANNOSE (UNII: PHA4727WTP)  
    POLOXAMER 338 (UNII: F75JV2T505)  
    PROPANEDIOL (UNII: 5965N8W85T)  
    HYDROXYETHOXYPHENYL BUTANONE (UNII: TH7XI54W45)  
    CAPRYLOYL SALICYLIC ACID (UNII: 5F7PJF6AA4)  
    CAPRYLYL GLYCOL (UNII: 00YIU5438U)  
    VITREOSCILLA LYSATE (UNII: 68DV8T89Y2)  
    CITRIC ACID (UNII: 2968PHW8QP)  
    TRISODIUM ETHYLENEDIAMINE DISUCCINATE (UNII: YA22H34H9Q)  
    MALTODEXTRIN (UNII: 7CVR7L4A2D)  
    XANTHAN GUM (UNII: TTV12P4NEE)  
    PENTYLENE GLYCOL (UNII: 50C1307PZG)  
    POLYSORBATE 80 (UNII: 6OZP39ZG8H)  
    ACRYLAMIDE/SODIUM ACRYLOYLDIMETHYLTAURATE COPOLYMER (120000 MPA.S AT 1%) (UNII: 5F4963KLHS)  
    PIROCTONE OLAMINE (UNII: A4V5C6R9FB)  
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:69625-926-011 in 1 CARTON05/14/2025
    140 mL in 1 TUBE; Type 0: Not a Combination Product
    2NDC:69625-926-021 in 1 CARTON05/14/2025
    23 mL in 1 TUBE; Type 0: Not a Combination Product
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    OTC Monograph DrugM00605/14/2025
    Labeler - COSMETIQUE ACTIVE PRODUCTION (282658798)
    Establishment
    NameAddressID/FEIBusiness Operations
    COSMETIQUE ACTIVE PRODUCTION282658798manufacture(69625-926)