DIFFERIN DARK SPOT CORRECTING SERUM- hydroquinone 2% solution 
Galderma Laboratories, L.P.

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.


Differin Dark Spot Correcting Serum
Galderma Laboratories, L.P.

Drug Facts

Active Ingredients

Hydroquinone 2% 


Skin Bleaching Agent


For the gradual fading of dark (brownish) discolorations in the skin such as freckles, age and liver spots.        


For external use only.

When using this product
■ Avoid contact with eyes.  ■ Some users of this product may experience a mild skin irritation. If skin irritation becomes severe, stop use and consult a doctor.

Do not use
■ on children under 12 years of age unless directed by a doctor.

Keep out of reach of children.
If swallowed, get medical help or contact a Poison Control Center right away.


Adults: Apply a small amount as a thin layer on the affected area twice daily, or use as directed by a doctor. If no improvement is seen after 3 months of treatment, use of this product should be discontinued. Lightening effect of this product may not be noticeable when used on very dark skin. 
■ Children under12 years of age: do not use unless directed by a doctor.
■ Sun exposure should be limited by using a sunscreen agent, a sun blocking agent, or protective clothing to cover bleached skin when using and after using this product in order to prevent darkening from reoccurring.

Inactive Ingredients

1,2-Hexanediol, Alcohol Denat., Caprylyl Glycol, Citric Acid, Disodium EDTA, Fragrance, Hippophae Rhamnoides Oil, Hydroxyethylcellulose, PEG-40 Hydrogenated Castor Oil, Polysorbate 20, Sodium Metabisulfite, Sodium Sulfite, Water

Questions or comments?


Distributed by:

Galderma Laboratories, L.P.

Fort Worth, TX 76177

All trademarks are the property of their respective owners.

Made in Canada


Principle Display Panel

Differin Dark Spot Serum Carton


Dark Spot
Correcting Serum

2% Hydroquinone
Skin Lightener

• Gradually fades dark brownish discoloration, pigment, spots and blotches 
• Helps reduce the appearance of post acne marks
• Improves luminosity

1 FL OZ (30 mL)

hydroquinone 2% solution
Product Information
Product TypeHUMAN OTC DRUGItem Code (Source)NDC:0299-4608
Route of AdministrationTOPICAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Hydroquinone (UNII: XV74C1N1AE) (Hydroquinone - UNII:XV74C1N1AE) Hydroquinone2 g  in 100 mL
Inactive Ingredients
Ingredient NameStrength
1,2-Hexanediol (UNII: TR046Y3K1G)  
Alcohol (UNII: 3K9958V90M)  
Caprylyl Glycol (UNII: 00YIU5438U)  
Citric Acid Monohydrate (UNII: 2968PHW8QP)  
Edetate Disodium (UNII: 7FLD91C86K)  
Hippophae Rhamnoides Seed Oil (UNII: T53SBG6741)  
Hydroxyethyl Cellulose (2000 Mpa.S At 1%) (UNII: S38J6RZN16)  
Polyoxyl 40 Hydrogenated Castor Oil (UNII: 7YC686GQ8F)  
Polysorbate 20 (UNII: 7T1F30V5YH)  
Sodium Metabisulfite (UNII: 4VON5FNS3C)  
Sodium Sulfite (UNII: VTK01UQK3G)  
Water (UNII: 059QF0KO0R)  
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:0299-4608-011 in 1 BOX05/07/201908/01/2021
130 mL in 1 BOTTLE, GLASS; Type 0: Not a Combination Product
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC monograph not finalpart358A05/07/201908/01/2021
Labeler - Galderma Laboratories, L.P. (047350186)
NameAddressID/FEIBusiness Operations
KIK Holdco Company Inc243547333manufacture(0299-4608)

Revised: 3/2022
Galderma Laboratories, L.P.