GLUCOSE (Dextrose) INJECTION, USP BAG

Instructions for Glucose (Dextrose) Injection

Please read the instructions carefully and use under the guidance of a physician.

Check carefully before use. Do not use if leakage is found, the drug liquid is unclear, or there are visible particles.

INGREDIENTS

This product is a sterilized aqueous solution of glucose.

General Name: Glucose injection

Molecular formula: C6H12O6·H2O

Molecular weight: 198.17

Auxiliary material name: Dilute hydrochloric acid

CHARACTER

This product is colorless or almost colorless clear liquid.

INDICATIONS

(1) Energy and fluid supplementation;It is used for underfeeding or massive fluid loss caused by various reasons (such as vomiting, diarrhea, etc.), total intravenous nutrition, and starvation ketosis.

(2) Drug diluents.

SPECIFICATION

（1）50ml:2.5g（2）50ml:5g（3）100ml：5g（4）100ml:10g（5）250ml:12.5g（6）250ml:25g（7）500ml:25g（8）500ml:50g（9）1000ml:50g（10）1000ml:100g

USAGE AND DOSAGE

Intravenous infusion. Medication as prescribed.

ADVERSE REACTIONS

1.Eating less, long-term simple supply of glucose solution can appear hypokalemia, hyponatremia and other electrolyte disorders. 2.Excessive infusion of this product may cause palpitations, arrhythmia, dyspnea, and even acute left heart failure in patients with cardiac insufficiency.

3.Hypophosphatemia is easy to occur when combined with insulin without paying attention to phosphate supplement.

4.Phlebitis may occur at the injection site.

【Taboos】

1. Uncontrolled diabetic ketoacidosis;

2. Hyperglycemic nonketotic hyperosmolar state.

PRECAUTIONS

1. Periodic paralysis, hypokalemia patients should be used with caution;

2. Stress or glucocorticoid induced hyperglycemia should be used with caution; Patients with edema, cardiac and renal insufficiency and liver cirrhosis ascites are prone to water retention, and the infusion volume should be controlled. Drip velocity should be controlled especially in patients with cardiac insufficiency.

3. Should be carefully checked before use, such as found leakage, solution turbidity, foreign bodies, etc., discarded.

4. Should be used in sterile conditions.

MEDICATION IN PREGNANT WOMEN AND LACTATING WOMEN

Too fast and too much fluid infusion may cause palpitation, arrhythmia and even acute left heart failure.

MEDICATION IN CHILDREN

Too fast and too much fluid infusion may cause palpitation, arrhythmia and even acute left heart failure.

MEDICATION IN THE ELDERLY

Too fast and too much fluid infusion may cause palpitation, arrhythmia and even acute left heart failure.

DRUG INTERACTIONS

The experiment was not performed and no reliable reference was available.

DRUG OVERDOSE

The experiment was not performed and no reliable reference was available.

PHARMACOLOGY AND TOXICOLOGY

Glucose is an important nutrient component of the human body. Every 1 gram of glucose can produce 4 kilocalories of heat energy, so it is used to supplement heat.

PHARMACOKINETICS

It can be converted into glycogen and fat for storage. The ability of a normal human body to utilize glucose is 6mg/kg per minute.

STORAGE

Sealed storage

VALIDITY

(1) The validity period of 250ml and 500ml products is 36 months.

(2) The validity period of 50ml, 100ml and 1000ml products is 24 months.

PACKAGE

1. Plastic infusion bag (non-PVC co-extrusion film, double hard pipe, easy to break apart, double valve and double plug). 50ml/ bag, 100ml/ bag, 250ml/ bag, 500ml/ bag, 1000ml/ bag. 2

. Plastic infusion bag (non-PVC co-extruded film, double hard tube, easy to break apart, double valve double plug, double layer sterile packaging). 50ml/ bag, 100ml/ bag, 250ml/ bag, 500ml/ bag, 1000ml/ bag.

OTHER INFORMATION

【Executive standard】

Pharmacopoeia of the People's Republic of China (2020, Volume II)

【Pharmaceutical marketing authorization holder】

Name: Huaren Pharmaceutical Co., Ltd. Registered Address: No. 187, Zhuzhou Road, Qingdao High-tech Park

【Manufacturer】Enterprise Name: Huaren Pharmaceutical Co., Ltd. Production Address: No. 187, Zhuzhou Road, Qingdao High-tech Park Zip code: 266101 Telephone number: 0532-67709071 0532-67709728 Fax number: 0532-88702625

HEALTH CARE PROVIDER LETTER pg.1

HEALTH CARE PROVIDER LETTER pg.2

HEALTH CARE PROVIDER LETTER pg.3

PACKAGE LABEL– Dextrose 5% 50 mL Bag Label

PACKAGE LABEL– Dextrose 5% 100 mL Bag Label

PACKAGE LABEL-Dextrose 5% 500 mL Bag Label

PACKAGE LABEL-Dextrose 5% 250 mL Bag Label

PACKAGE LABEL-Dextrose 5% 1000 mL Bag Label