Label: HEAD AND SHOULDERS 2IN1 ADVANCED SCALP CARE 2IN1- pyrithione zinc lotion/shampoo

  • NDC Code(s): 84126-022-11
  • Packager: The Procter & Gamble Manufacturing Company
  • Category: HUMAN OTC DRUG LABEL
  • DEA Schedule: None

Drug Label Information

Updated September 21, 2026

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  • SPL UNCLASSIFIED SECTION

    Drug Facts

  • Active ingredient

    Pyrithione zinc 1%

  • Purpose

    Anti-dandruff

  • Uses

    helps prevent recurrence of flaking and itching associated with dandruff.

  • Warnings

    For external use only.

    When using this product

    • avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.

    Stop use and ask a doctor if

    • condition worsens or does not improve after regular use of this product as directed.

    Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

  • Directions

    • for best results use at least twice a week or as directed by a doctor.
    • for maximum dandruff control, use every time you shampoo.
    • shake before use.
    • wet hair, massage onto scalp, rinse, repeat if desired.
  • Inactive ingredients

    water, sodium laureth sulfate, sodium lauryl sulfate, cocamidopropyl betaine, sodium xylenesulfonate, zinc carbonate, glycol distearate, fragrance, sodium chloride, dimethiconol, dimethicone, sodium benzoate, guar hydroxypropyltrimonium chloride, piroctone olamine, TEA-dodecylbenzenesulfonate, glycerin, trideceth-10, butylene glycol, magnesium carbonate hydroxide, pentylene glycol, neosetophoma cerealis extract, aloe barbadensis leaf juice, niacinamide, tocopheryl acetate, cocos nucifera (coconut) fruit juice, benzyl alcohol, methylchloroisothiazolinone, methylisothiazolinone

  • Questions (or comments)?

    1-800-723-9569

  • SPL UNCLASSIFIED SECTION

    Dist. by PROCTER & GAMBLE,
    CINCINNATI, OH 45202

  • PRINCIPAL DISPLAY PANEL - 1.18 L Bottle Label

    head &

    shoulders ®

    pyrithione zinc dandruff

    shampoo + conditioner

    2in1

    ADVANCED
    SCALP CARE

    WITH ALOE VERA, COCONUT WATER

    HydraZinc COMPLEX


    40 FL OZ (1.18 L)

    HS

  • INGREDIENTS AND APPEARANCE
    HEAD AND SHOULDERS 2IN1 ADVANCED SCALP CARE 2IN1 
    pyrithione zinc lotion/shampoo
    Product Information
    Product TypeHUMAN OTC DRUGItem Code (Source)NDC:84126-022
    Route of AdministrationTOPICAL
    Active Ingredient/Active Moiety
    Ingredient NameBasis of StrengthStrength
    PYRITHIONE ZINC (UNII: R953O2RHZ5) (PYRITHIONE ZINC - UNII:R953O2RHZ5) PYRITHIONE ZINC1 g  in 100 mL
    Inactive Ingredients
    Ingredient NameStrength
    SODIUM LAURETH SULFATE (UNII: BPV390UAP0)  
    SODIUM LAURYL SULFATE (UNII: 368GB5141J)  
    DIMETHICONE (UNII: 92RU3N3Y1O)  
    ZINC CARBONATE (UNII: EQR32Y7H0M)  
    GLYCOL DISTEARATE (UNII: 13W7MDN21W)  
    SODIUM XYLENESULFONATE (UNII: G4LZF950UR)  
    SODIUM CHLORIDE (UNII: 451W47IQ8X)  
    SODIUM BENZOATE (UNII: OJ245FE5EU)  
    MAGNESIUM CARBONATE HYDROXIDE (UNII: YQO029V1L4)  
    COCAMIDOPROPYL BETAINE (UNII: 5OCF3O11KX)  
    TEA-DODECYLBENZENESULFONATE (UNII: 8HM7ZD48HN)  
    METHYLCHLOROISOTHIAZOLINONE (UNII: DEL7T5QRPN)  
    ALPHA-TOCOPHEROL ACETATE (UNII: 9E8X80D2L0)  
    COCOS NUCIFERA (COCONUT) FRUIT JUICE (UNII: AMN6S4M09G)  
    NIACINAMIDE (UNII: 25X51I8RD4)  
    BENZYL ALCOHOL (UNII: LKG8494WBH)  
    METHYLISOTHIAZOLINONE (UNII: 229D0E1QFA)  
    TRIDECETH-10 (UNII: G624N6MSBA)  
    DIMETHICONOL (50000 CST) (UNII: R2285D73YT)  
    ALOE BARBADENSIS LEAF JUICE (UNII: RUE8E6T4NB)  
    GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE (1.7 SUBSTITUENTS PER SACCHARIDE) (UNII: B16G315W7A)  
    WATER (UNII: 059QF0KO0R)  
    BUTYLENE GLYCOL (UNII: 3XUS85K0RA)  
    GLYCERIN (UNII: PDC6A3C0OX)  
    PENTYLENE GLYCOL (UNII: 50C1307PZG)  
    PIROCTONE OLAMINE (UNII: A4V5C6R9FB)  
    Packaging
    #Item CodePackage DescriptionMarketing Start DateMarketing End Date
    1NDC:84126-022-111180 mL in 1 BOTTLE, PUMP; Type 0: Not a Combination Product02/20/2024
    Marketing Information
    Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
    OTC Monograph DrugM03202/20/2024
    Labeler - The Procter & Gamble Manufacturing Company (004238200)
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