CERON DM - chlorpheniramine maleate, phenylephrine hydrochloride and dextromethorphan hydrobromide syrup 
Cypress Pharmaceutical, Inc.

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.


Drug Facts

Active ingredients
(in each 5 mL teaspoonful)

Chlorpheniramine Maleate 4 mg
Phenylephrine Hydrochloride 12.5 mg
Dextromethorphan Hydrobromide 15 mg




temporarily relieves these symptoms due to the common cold, hay fever (allergic rhinitis) or other upper respiratory allergies:


Do not exceed recommended dosage.

Do not use this product

  • if you are now taking a prescription monoamie oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug.  If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product

Ask a doctor before use if you have

  • a breathing problem such as emphysema or chronic bronchitis
  • glaucoma
  • trouble urinating due to an enlarged prostate gland
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes mellitus
  • a cough that lasts or is chronic such as occurs with smoking, asthma or emphysema
  • a cough that occurs with too much phlegm (mucus)

Ask a doctor or pharmacist before use if you are

taking sedatives or tranquilizers.

When using this product

  • excitability may occur, especially in children
  • you may get drowsy
  • avoid alcoholic drinks
  • alcohol, sedatives, and tranquilizers may increase drowsiness
  • be careful when driving a motor vehicle or operating machinery

Stop use and ask a doctor if

  • nervousness, dizziness, or sleeplessness occur
  • cough or nasal congestion persists for more than 1 week, tends to recur, or is accompanied by a fever, rash, or persistent headache.  These could be signs of a serious condition.
  • new symptoms occur

If pregnant or breast-feeding,

ask a health professional before use.

Keep out of the reach of children.

In case of accidental overdose seek medical help or contact a Poison Control Center immediately.


Do not exceed recommended dosage.
Adults and children
12 years of age
and older:

1 teaspoonful (5 mL)
every 6 hours, not
to exceed 4 teaspoonfuls
in 24 hours.
Children 6 to under
12 years of age:

1/2 teaspoonfuls
every 6 hours,
not to exceed 2
in 24 hours.
Children under
6 years of age:
Consult a

Other information

Store at 68°- 77°F(20°- 25°C)

Inactive ingredients

FD and C Blue #1, FD and C Red #40, Glycerin, Grape Flavor, Propylene Glycol, Purified Water, Sodium Citrate, Sodium Saccharin, Sorbitol.

Questions? Comments?

M-F:  8:00 a.m.- 5:00 p.m. CT
Serious side effects associated with use of this product may be reported to this number.

Manufactured for:
Cypress Pharmaceuticals, Inc.
Madison, MS  39110

I297                   Rev. 03/09

Product Packaging

The packaging below represents the labeling currently used:

Principal display panel and side panel for 473 mL label:

NDC 60258-415-16



Each teaspoonful (5 mL) for oral administration

Chlorpheniramine Maleate...........................4.0 mg
Phenylephrine HCl....................................12.5 mg
Dextromethorphan HBr..............................15.0 mg

Grape Flavor

Sugar Free/Alcohol Free


16 fl oz (473 mL)

Tamper evident by foil seal under cap. Do not use if foil
seal is broken or missing.

Supplied in a tight, light-resistant container with a
child-resistant cap.


Mfg. for:  Cypress Pharmaceutical, Inc.
Madison, MS  39110

L591                               Rev. 03/09

CERON-DM Packaging

CERON-DM Packaging

chlorpheniramine maleate, phenylephrine hydrochloride, dextromethorphan hydrobromide syrup
Product Information
Product Type HUMAN OTC DRUG Item Code (Source) NDC:60258-415
Route of Administration ORAL DEA Schedule     
Active Ingredient/Active Moiety
Ingredient Name Basis of Strength Strength
Chlorpheniramine Maleate (Chlorpheniramine) Chlorpheniramine Maleate 4.0 mg  in 5 mL
Phenylephrine Hydrochloride (Phenylephrine) Phenylephrine Hydrochloride 12.5 mg  in 5 mL
Dextromethorphan Hydrobromide (Dextromethorphan) Dextromethorphan Hydrobromide 15.0 mg  in 5 mL
Inactive Ingredients
Ingredient Name Strength
Propylene Glycol  
Sodium Citrate  
Saccharin Sodium  
Product Characteristics
Color      Score     
Shape Size
Flavor GRAPE Imprint Code
# Item Code Package Description Multilevel Packaging
1 NDC:60258-415-16 473 mL in 1 BOTTLE None
2 NDC:60258-415-04 118 mL in 1 BOTTLE None

Marketing Information
Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date
OTC monograph final part341 01/01/2006 08/26/2011

Labeler - Cypress Pharmaceutical, Inc. (790248942)

Revised: 08/2011 Cypress Pharmaceutical, Inc.