JUXTAPID- lomitapide mesylate capsule 
Aegerion Pharmaceuticals, Inc.

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MEDICATION GUIDE

JUXTAPID® (JUKS-tuh-pid)
(lomitapide)
capsules

Read this Medication Guide before your treatment.

What is the most important information I should know about JUXTAPID?

There is a registry that collects information about the effects of taking JUXTAPID over time. Ask your doctor for more information about this registry or visit www.JUXTAPID.com or call 1-877-902-4099.

JUXTAPID may cause serious side effects including:

1. Liver problems. JUXTAPID can cause liver problems.

2. Harm to your unborn baby. JUXTAPID may cause harm to your unborn baby.

What is JUXTAPID?

JUXTAPID is a prescription medicine used along with diet and other lipid-lowering treatments, including low-density lipoprotein (LDL) apheresis where available, in people with homozygous familial hypercholesterolemia (HoFH) to reduce:

It is not known if JUXTAPID can decrease problems from high cholesterol, such as heart attack, stroke, death or other health problems.

It is not known if JUXTAPID is safe in people with high cholesterol but who do not have HoFH.

JUXTAPID should not be taken with certain medicines or food. You should not drink grapefruit juice. Ask your doctor or pharmacist to make sure you can take JUXTAPID with your other medicines, and tell your doctor about any new medicines you might take even for only a short time.

It is not known if JUXTAPID is safe and effective in people with kidney problems including people with end-stage kidney disease who are not on dialysis.

It is not known if JUXTAPID is safe and effective when used in children under the age of 18.

Who should not take JUXTAPID?

Do not take JUXTAPID if you:

What should I tell my doctor before taking JUXTAPID?

Before you take JUXTAPID, tell your doctor if you:

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Before starting a new medicine while taking JUXTAPID, even if you will only be taking it for a short time, ask your doctor or pharmacist if it is safe to take with JUXTAPID.

JUXTAPID may affect the way other medicines work, and other medicines may affect how JUXTAPID works.

Certain medicines can affect how your liver breaks down other medicines.

Especially tell your doctor if you take:

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

How should I take JUXTAPID?

What are the possible side effects of JUXTAPID?

JUXTAPID can cause serious side effects, including:

The most common side effects of JUXTAPID include:

Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of JUXTAPID. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store JUXTAPID?

Keep JUXTAPID and all medicines out of the reach of children.

General information about the safe and effective use of JUXTAPID

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use JUXTAPID for a condition for which it was not prescribed. Do not give JUXTAPID to other people, even if they have the same symptoms you have. It may harm them.

This Medication Guide summarizes the most important information about JUXTAPID. If you would like more information, talk with your doctor. You can ask your pharmacist or doctor for information about JUXTAPID that is written for healthcare professionals.

For more information, go to www.JUXTAPID.com or call 1-85-JUXTAPID (1-855-898-2743).

What are the ingredients in JUXTAPID?

Active ingredient: lomitapide

Inactive ingredients: pregelatinized starch, sodium starch glycolate, microcrystalline cellulose, lactose monohydrate, silicon dioxide, magnesium stearate

Capsule shell: gelatin, titanium dioxide, edible black ink for printing and may contain red iron oxide

This Medication Guide has been approved by the U.S. Food and Drug Administration.

JUXTAPID is a registered trademark of Aegerion Pharmaceuticals, Inc.

Manufactured for:

Aegerion Pharmaceuticals, Inc.
Cambridge, MA 02142

08/14
© Aegerion

Revised: 08/2014
 
Aegerion Pharmaceuticals, Inc.