PONSTEL- mefenamic acid capsule 
Shionogi Inc.

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MEDICATION GUIDE

for Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

(See the end of this Medication Guide for a list of prescription NSAID medicines.)

What is the most important information I should know about medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)?

NSAID medicines may increase the chance of a heart attack or stroke that can lead to death.

This chance increases:

NSAID medicines should never be used right before or after a heart surgery called a "coronary artery bypass graft (CABG)."

NSAID medicines can cause ulcers and bleeding in the stomach and intestines at any time during treatment.

Ulcers and bleeding:

The chance of a person getting an ulcer or bleeding increases with:

NSAID medicines should only be used:

What are Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)?

NSAID medicines are used to treat pain and redness, swelling, and heat (inflammation) from medical conditions such as:

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)?

Do not take an NSAID medicine:

Tell your healthcare provider:

What are the possible side effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)?

Serious side effects include:Other side
• heart attackeffects include:
• stroke• stomach pain
• high blood pressure• constipation
• heart failure from body swelling (fluid retention)• diarrhea
• kidney problems including kidney failure• gas
• bleeding and ulcers in the stomach and intestine• heartburn
• low red blood cells (anemia)• nausea
• life-threatening skin reactions• vomiting
• life-threatening allergic reactions• dizziness
• liver problems including liver failure
• asthma attacks in people who have asthma

Get emergency help right away if you have any of the following symptoms:

Stop your NSAID medicine and call your healthcare provider right away if you have any of the following symptoms:

•nausea•there is blood in your bowel movement or it is black and sticky like tar
•more tired or weaker than usual•unusual weight gain
•itching•stomach pain
•your skin or eyes look yellow•skin rash or blisters with fever
•flu-like symptoms•swelling of the arms and legs, hands and feet
•vomit blood

These are not all the side effects with NSAID medicines. Talk to your healthcare provider or pharmacist for more information about NSAID medicines.

Other information about Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

NSAID medicines that need a prescription

Generic NameTradename
CelecoxibCelebrex
DiclofenacCataflam, Voltaren, Arthrotec (combined with misoprostol)
DiflunisalDolobid
EtodolacLodine, Lodine XL
FenoprofenNalfon, Nalfon 200
FlurbiprofenAnsaid
IbuprofenMotrin, Tab-Profen, Vicoprofen* (combined with hydrocodone), Combunox (combined with oxycodone)
IndomethacinIndocin, Indocin SR, Indo-Lemmon, Indomethagan
KetoprofenOruvail
KetorolacToradol
Mefenamic AcidPONSTEL
MeloxicamMobic
NabumetoneRelafen
NaproxenNaprosyn, Anaprox, Anaprox DS, EC-Naprosyn, Naprelan, Naprapac (copackaged with lansoprazole)
OxaprozinDaypro
PiroxicamFeldene
SulindacClinoril
TolmetinTolectin, Tolectin DS, Tolectin 600


*Vicoprofen contains the same dose of ibuprofen as over-the-counter (OTC) NSAIDs, usually used for less than 10 days to
treat pain. The OTC NSAID label warns that long term continuous use may increase the risk of heart attack or stroke.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or call
Shionogi Inc. at 1-800-849-9707.
This Medication Guide has been approved by the U.S. Food and Drug Administration.

PONS-PI/MG-01
Revised 05/2013

Revised: 09/2013
 
Shionogi Inc.