THERAPROXEN-500 - naproxen, .gamma.-aminobutyric acid
Physician Therapeutics LLC
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
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MEDICATION GUIDE FOR NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS)
(See the end of this Medication Guide for a list of prescription NSAID medicines.)
What is the most important information I should know about medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)?
NSAID medicines may increase the chance of a heart attack or stroke that can lead to death. This chance increases:
- with longer use of NSAID medicines
- in people who have heart disease
NSAID medicines should never be used right before or after a heart surgery called a “coronary artery bypass graft (CABG).”
NSAID medicines can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Ulcers and bleeding:
- can happen without warning symptoms
- may cause death
The chance of a person getting an ulcer or bleeding increases with:
- taking medicines called “corticosteroids” and “anticoagulants”
- longer use
- smoking
- drinking alcohol
- older age
- having poor health
NSAID medicines should only be used:
- exactly as prescribed
- at the lowest dose possible for your treatment
- for the shortest time needed
What are Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)?
NSAID medicines are used to treat pain and redness, swelling, and heat (inflammation) from medical conditions such as:
- different types of arthritis
- menstrual cramps and other types of short-term pain
Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)?
Do not take an NSAID medicine:
- if you had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine
- for pain right before or after heart bypass surgery
Tell your healthcare provider:
- about all your medical conditions.
- about all of the medicines you take. NSAIDs and some other medicines can interact with each other and cause serious side effects.
Keep a list of your medicines to show to your healthcare provider and pharmacist.
- if you are pregnant. NSAID medicines should not be used by pregnant women late in their pregnancy.
- if you are breastfeeding. Talk to your doctor.
What are the possible side effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)?
Serious side effects include: | Other side effects include: |
heart attack | stomach pain |
stroke | constipation |
high blood pressure | diarrhea |
heart failure from body swelling (fluid retention) | gas |
kidney problems including kidney failure | heartburn |
bleeding and ulcers in the stomach and intestine | nausea |
low red blood cells (anemia) | vomiting |
life-threatening skin reactions | dizziness |
life-threatening allergic reactions |
|
liver problems including liver failure |
|
asthma attacks in people who have asthma |
|
Generic Name | Tradename |
Celecoxib | Celebrex® |
Diclofenac | Cataflam®, Voltaren®, Arthrotec™ (combined with misoprostol) |
Diflunisal | Dolobid® |
Etodolac | Lodine®, Lodine® XL |
Fenoprofen | Nalfon®, Nalfon® 200 |
Flurbirofen | Ansaid® |
Ibuprofen | Motrin®, Tab-Profen®, Vicoprofen** (combined with hydrocodone), CombunoxTM (combined with oxycodone) |
Indomethacin | Indocin®, Indocin® SR, Indo-Lemmon™, Indomethagan™ |
Ketoprofen | Oruvail® |
Ketorolac | Toradol® |
Mefenamic Acid | Ponstel® |
Meloxicam | Mobic® |
Nabumetone | Relafen® |
Naproxen | Naprosyn®, Anaprox®, Anaprox® DS, EC-Naproxyn®, Naprelan®, Naprapac ® (copackaged with lansoprazole) |
Oxaprozin | Daypro® |
Piroxicam | Feldene® |
Sulindac | Clinoril® |
Tolmetin | Tolectin®, Tolectin DS®, Tolectin® 600 |
* Vicoprofen contains the same dose of ibuprofen as over-the-counter (OTC) NSAID, and is usually used for less than 10 days to treat pain. The OTC NSAID label warns that long term continuous use may increase the risk of heart attack or stroke | * Vicoprofen contains the same dose of ibuprofen as over-the-counter (OTC) NSAID, and is usually used for less than 10 days to treat pain. The OTC NSAID label warns that long term continuous use may increase the risk of heart attack or stroke |