SIGNIFOR- pasireotide injection 
Novartis Pharmaceuticals Corporation

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Medication Guide

SIGNIFOR® [sig-na-for]

(pasireotide)

Injection

Read this Medication Guide before you start using SIGNIFOR and each time you get a refill. There may be new information. This information does not take the place of talking to your doctor about your medical condition or your treatment. 

What is the most important information I should know about SIGNIFOR?

SIGNIFOR can cause serious side effects, including:

If you get hypocortisolism while taking SIGNIFOR, your doctor may change your dose or ask you to stop taking it.


If you get hyperglycemia while taking SIGNIFOR, your doctor may give you another medicine to take to lower your blood sugar. Your doctor may also change your dose of SIGNIFOR or ask you to stop taking it.

What is SIGNIFOR?

SIGNIFOR is a prescription medicine used to treat Cushing’s disease in adults who cannot have surgery or have failed surgery.

It is not known if SIGNIFOR is safe and effective in children.

What should I tell my doctor before using SIGNIFOR?

Before you take SIGNIFOR, tell your doctor if you:

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Taking SIGNIFOR with certain other medicines can affect each other and cause side effects. Especially tell your doctor if you take:

Ask your doctor for a list of these medicines, if you are not sure.

Know the medicines you take. Keep a list of them to show to your doctor and pharmacist when you get a new medicine.

How should I use SIGNIFOR?

What are the possible side effects of SIGNIFOR?

SIGNIFOR may cause serious side effects, including:

The most common side effects of SIGNIFOR include: 

Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of SIGNIFOR. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1–800–FDA–1088.

How should I store SIGNIFOR?

Keep SIGNIFOR and all medicines out of the reach of children.

General information about the safe and effective use of SIGNIFOR.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use SIGNIFOR for a condition for which it was not prescribed. Do not give SIGNIFOR to other people, even if they have the same symptoms that you have. It may harm them.

This Medication Guide summarizes the most important information about SIGNIFOR. If you would like more information, talk to your doctor. You can ask your pharmacist or doctor for information about SIGNIFOR that is written for health professionals.

For more information go to www.SIGNIFOR.com or call 1-877-503-3377.

What are the ingredients in SIGNIFOR?

Active ingredient: Pasireotide

Inactive ingredients: Mannitol, tartaric acid, sodium hydroxide and water for injection.

T2012-224
December 2012

Revised: 12/2012
 
Novartis Pharmaceuticals Corporation