Inactive Ingredients

acacia, citric acid, hydrochloric acid, natural and artificial vanilla flavor, polysorbate 80, potassium chloride, potassium sorbate, purified water, saccharin sodium, simethicone emulsion, sodium benzoate, sodium carrageenan, sodium citrate, sorbitol solution and xanthan gum.

Oral Administration

This product should not be used in patients with known gastric or intestinal perforation or hypersensitivity to barium sulfate products.

Rectal Administration

This product should not be used in patients with known intestinal perforation or hypersensitivity to barium sulfate products.

General

Diagnostic procedures which involve the use of radiopaque contrast agents should be carried out under the direction of personnel with the requisite training and with a thorough knowledge of the particular procedure to be performed. A history of bronchial asthma, atopy, as evidenced by hay fever and eczema, or a previous reaction to a contrast agent, warrant special attention. Caution should be exercised with the use of radiopaque media in severely debilitated patients and in those with marked hypertension or advanced cardiac disease.

Ingestion of this product is not recommended in patients with a history of food aspiration. If barium studies are required in these patients or in patients in whom integrity of the swallowing mechanism is unknown, proceed with caution. If this product is aspirated into the larynx, further administration should be immediately discontinued.

After any barium study of the GI tract, it is important to rehydrate the patient as quickly as possible to prevent impaction of the bowel by barium sulfate. To prevent barium sulfate impaction in the bowel, the use of mild laxatives such as milk of magnesia or lactulose, following completion of the examination may also be required. These mild laxatives are recommended on a routine basis and in patients with a history of constipation unless contraindicated.

Oral Administration

Use with caution in patient with complete or nearly complete obstruction of the gastrointestinal tract.

Rectal Administration

Use with caution when obstructive lesions of the colon are suspected. Care should be taken to minimize the amount of barium sulfate allowed to flow proximal to obstructive lesions of the colon. When used rectally, care must be taken during insertion of the enema tip into the patient, since forceful or too deep insertion may cause tearing or perforation of the rectum.

Information for Patients

Before administration of this product patients should be instructed to:

1. Inform their physician if they are pregnant.
2. Inform their physician if they are allergic to any drugs or food, or if they have had any prior reactions to barium sulfate products or other contrast agents used in x-ray procedures (see PRECAUTIONS - General).
3. Inform their physician about any other medications they are currently taking.

Drug Interactions

The presence of barium sulfate formulations in the GI tract may alter the absorption of therapeutic agents taken concomitantly. In order to minimize any potential change in absorption, the separate administration of barium sulfate from that of other agents should be considered.

Usage in Pregnancy

Radiation is known to cause harm to the unborn fetus exposed in utero. Therefore, radiographic procedures should only be used when, in the judgement of the physician, their use is deemed essential to the welfare of the pregnant patient.

Nursing Mothers

Barium sulfate products may be used during lactation.

General

The volume and concentration of LIQUID POLIBAR PLUS® to be administered will depend on the degree and extent of contrast required in the area(s) under examination and on the equipment and technique employed. See applicable system below for typical adult dose.

Patient Preparation for Colon Examinations

In order to achieve optimum results, the colon must be cleansed prior to the use of a barium enema. This is usually accomplished by placing the patient on a low fat, low residue diet, combined with the use of laxatives and/or cathartics. A cleansing enema may also be used unless contraindicated.

Single Contrast Colon Studies

Dilute 1 part LIQUID POLIBAR PLUS® with 5 parts water to yield approximately 17.5% w/v, 15% w/w; or dilute as required.
Typical Adult Dose: 1000 mL to 2500 mL of diluted suspension.

Double Contrast Colon Studies

Use undiluted.
Typical Adult Dose: 500 mL to 1500 mL or as directed by a physician.

Esophagus and Cardiac Series

Undiluted LIQUID POLIBAR PLUS® should be administered orally for double-contrast examination of the esophagus. Films are taken during rapid swallowing of barium sulfate.
Typical Adult Dose: 60 mL to 300 mL

Stomach

LIQUID POLIBAR PLUS® can be used for single or double-contrast examination of the stomach. It can be used undiluted or diluted 1:1 with water to produce a 52.5% w/v. Diluted LIQUID POLIBAR PLUS® is highly suited for a biphasic examination of the stomach. Following completion of the double-contrast examination of the stomach using E-Z-HD™ barium sulfate, undiluted or diluted 1:1 with water, LIQUID POLIBAR PLUS® may be used for the single phase of the study.
Typical Adult Dose: 150 mL to 340 mL of diluted or undiluted as applicable.

Small Bowel Series

LIQUID POLIBAR PLUS® can be used for small bowel series. It can be given alone or can be used following the completion of a double-contrast examination of the stomach using E-Z-HD™. It may be given either undiluted or in 1:1 dilution. Higher dilution will decrease the density of the barium sulfate but will increase the speed of the flow of contrast.
Typical Adult Dose: 340 mL to 750 mL of diluted or undiluted as applicable.