CLEAN AND CLEAR ADVANTAGE ACNE CONTROL- benzoyl peroxide, salicylic acid 
Johnson & Johnson Consumer Inc.

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

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Clean & Clear Advantage Acne Control Cleanser

Drug Facts

Active Ingredient

Benzoyl Peroxide (10%)

Purpose

Acne Medication

Use

  • For the treatment of acne

Warnings

For external use only.

When using this product - Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. – Avoid unnecessary sun exposure and use a sunscreen. Avoid contact with the eyes, lips and mouth – Avoid contact with hair or dyed fabrics, which may be bleached by this product – Skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration.

Do not use if you – Have very sensitive skin – Are sensitive to benzoyl peroxide.

Stop use and ask a doctor if – irritation becomes severe

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. Avoid contact with eyes. If contact occurs, flush thoroughly with water.

Directions

  • Wet face. Gently massage all over face for 20-30 seconds, avoiding eye area. Rinse thoroughly and pat dry.
  • Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor
  • If bothersome dryness or peeling occurs, reduce application to once a day or every other day.
  • If going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor.

Other Information

- Keep tightly closed. Avoid storing at temperatures above 90°F.

Inactive Ingredients

Glycerin, Petrolatum, Water, C12-15 Alkyl Benzoate, Mineral Oil, Sodium Cocoyl Isethionate, Zinc Lactate, Sodium C14-16 Olefin Sulfonate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Potassium Polyphosphate, Menthol, Fragrance, Titanium Dioxide, Carbomer

Questions

877-754-6411: Outside US dial collect 215-273-8755 or visit www.CleanandClear.com

Clean & Clear Advantage Acne Control Moisturizer

Drug Facts

Active Ingredient

Salicylic Acid (0.5%)

Purpose

Acne Medication

Use

  • For the treatment of acne

Warnings

For external use only.

When using this product - Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. - Rinse right away with water if it gets in eyes.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

  • Clean the skin thoroughly before applying this product.
  • Cover the entire affected area with a thin layer one to three times daily
  • Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor
  • If bothersome dryness or peeling occurs, reduce application to once a day or every other day.

Inactive Ingredients

Water, C12-15 Alkyl Benzoate, Cetearyl Alcohol, Dimethicone, PPG-10 Cetyl Ether, Methyl Gluceth-20, C12-15 Alkyl Lactate, Polysorbate 60, Glycine Soja (Soybean) Seed Extract, Phenyl Trimethicone, Isoceteth-20, Steareth-21, Polyacrylamide, Ethylene/Acrylic Acid Copolymer, Cetyl Lactate, Phenoxyethanol, Glycerin, Cocamidopropyl PG-Dimonium Chloride Phosphate, Fragrance, C13-14 Isoparaffin, Cetearyl Glucoside, Laureth-7, Disodium EDTA, Benzalkonium Chloride, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Propylene Glycol, Butylene Glycol, Capryloyl Glycine, Sarcosine, Cinnamomum Zeylanicum Bark Extract, Cedrus Atlantica Bark Extract, Portulaca Oleracea Extract

Questions

877-754-6411: Outside US dial collect 215-273-8755 or visit www.CleanandClear.com

Clean & Clear Advantage Fast Clearing Spot Treatment

Drug Facts

Active Ingredient

Salicylic Acid (2%)

Purpose

Acne Medication

Use

  • For the treatment of acne

Warnings

For external use only. Flammable, keep away from open fire or flame

When using this product - Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center immediately. Avoid contact with eyes. If contact occurs, flush thoroughly with water.

Directions

  • Cleanse thoroughly before applying this product.
  • Cover the entire affected area with a thin layer one to three times daily
  • Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor
  • If bothersome dryness or peeling occurs, reduce application to once a day or every other day.

Inactive Ingredients

Water, SD Alcohol 40-B, Hamamelis Virginiana (Witch Hazel) Water, Polyacrylamide, Glycerin, C13-14 Isoparaffin , Cyclopentasiloxane, C12-15 Alkyl Lactate , Alcohol, Laureth-7,Phenoxyethanol, Cetyl Lactate , PPG-2 Isoceteth-20 Acetate, Cocamidopropyl PG-Dimonium Chloride Phosphate, Polysorbate 20, Phenethyl Dimethicone, Fragrance, Dehydroxanthan Gum , Propylene Glycol, Benzalkonium Chloride, Ammonium Hydroxide, Tetrasodium EDTA, Butylene Glycol , Capryloyl Glycine, Sarcosine, Cinnamomum Zeylanicum Bark Extract, Cedrus Atlantica Bark Extract , Portulaca Oleracea Extract

Questions

877-754-6411: Outside US dial collect 215-273-8755 or visit www.CleanandClear.com

Distributed in the US by:
JOHNSON & JOHNSON
CONSUMER PRODUCTS COMPANY
Division of Johnson & Johnson
Consumer Companies, Inc.
Skillman, NJ 08558-9418

PRINCIPAL DISPLAY PANEL - Kit Carton

Clean
&
Clear®

advantage®
acne
control kit

100% of people
had clearer skin
in as little as 1 day
open lid to see results

benzoyl peroxide acne cleanser 4 FL. OZ. (118 mL)
salicylic acid acne medication moisturizer 2 FL. OZ. (59mL)
salicylic acid acne medicine treatment 0.5 FL. OZ. (15mL)

CLEAN & CLEAR® advantage®

PRINCIPAL DISPLAY PANEL -  Kit Carton
CLEAN AND CLEAR ADVANTAGE ACNE CONTROL 
benzoyl peroxide, salicylic acid kit
Product Information
Product TypeHUMAN OTC DRUGItem Code (Source)NDC:58232-0633
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:58232-0633-91 in 1 CARTON
Quantity of Parts
Part #Package QuantityTotal Product Quantity
Part 11 TUBE 118 mL
Part 21 TUBE 59 mL
Part 31 TUBE 15 mL
Part 1 of 3
CLEAN AND CLEAR ADVANTAGE ACNE CONTROL  CLEANSER
benzoyl peroxide lotion
Product Information
Route of AdministrationTOPICAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Benzoyl Peroxide (UNII: W9WZN9A0GM) (Benzoyl Peroxide - UNII:W9WZN9A0GM) Benzoyl Peroxide100 mg  in 1 mL
Inactive Ingredients
Ingredient NameStrength
Glycerin (UNII: PDC6A3C0OX)  
Petrolatum (UNII: 4T6H12BN9U)  
Water (UNII: 059QF0KO0R)  
Alkyl (C12-15) Benzoate (UNII: A9EJ3J61HQ)  
Mineral Oil (UNII: T5L8T28FGP)  
Sodium Cocoyl Isethionate (UNII: 518XTE8493)  
Zinc Lactate (UNII: 2GXR25858Y)  
Sodium C14-16 Olefin Sulfonate (UNII: O9W3D3YF5U)  
Potassium Metaphosphate (UNII: 01DMT14Z63)  
Menthol (UNII: L7T10EIP3A)  
Titanium Dioxide (UNII: 15FIX9V2JP)  
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1118 mL in 1 TUBE; Type 0: Not a Combination Product
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC monograph finalpart333D05/09/2012
Part 2 of 3
CLEAN AND CLEAR ADVANTAGE ACNE CONTROL MOISTURIZER 
salicylic acid lotion
Product Information
Item Code (Source)NDC:58232-0632
Route of AdministrationTOPICAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Salicylic Acid (UNII: O414PZ4LPZ) (Salicylic Acid - UNII:O414PZ4LPZ) Salicylic Acid5 mg  in 1 mL
Inactive Ingredients
Ingredient NameStrength
Water (UNII: 059QF0KO0R)  
Alkyl (C12-15) Benzoate (UNII: A9EJ3J61HQ)  
Cetostearyl Alcohol (UNII: 2DMT128M1S)  
Dimethicone (UNII: 92RU3N3Y1O)  
PPG-10 Cetyl Ether (UNII: Q056X4917J)  
Methyl Gluceth-20 (UNII: J3QD0LD11P)  
Polysorbate 60 (UNII: CAL22UVI4M)  
Soybean (UNII: L7HT8F1ZOD)  
Phenyl Trimethicone (UNII: DR0K5NOJ4R)  
Isoceteth-20 (UNII: O020065R7Z)  
Steareth-21 (UNII: 53J3F32P58)  
Cetyl Lactate (UNII: A7EVH2RK4O)  
Phenoxyethanol (UNII: HIE492ZZ3T)  
Glycerin (UNII: PDC6A3C0OX)  
Cocamidopropyl PG-Dimonium Chloride Phosphate (UNII: H2KVQ74JM4)  
C13-14 Isoparaffin (UNII: E4F12ROE70)  
Cetearyl Glucoside (UNII: 09FUA47KNA)  
Laureth-7 (UNII: Z95S6G8201)  
Edetate Disodium (UNII: 7FLD91C86K)  
Benzalkonium Chloride (UNII: F5UM2KM3W7)  
Propylene Glycol (UNII: 6DC9Q167V3)  
Butylene Glycol (UNII: 3XUS85K0RA)  
Capryloyl Glycine (UNII: 8TY5YO42NJ)  
Sarcosine (UNII: Z711V88R5F)  
Cinnamon Bark Oil (UNII: XE54U569EC)  
Cedrus Atlantica Bark (UNII: ITP1Q41UPF)  
Purslane (UNII: M6S840WXG5)  
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:58232-0632-259 mL in 1 TUBE; Type 0: Not a Combination Product
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC monograph finalpart333D05/09/2012
Part 3 of 3
CLEAN AND CLEAR ADVANTAGE FAST CLEARING SPOT TREATMENT 
salicylic acid lotion
Product Information
Route of AdministrationTOPICAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Salicylic Acid (UNII: O414PZ4LPZ) (Salicylic Acid - UNII:O414PZ4LPZ) Salicylic Acid20 mg  in 1 mL
Inactive Ingredients
Ingredient NameStrength
Water (UNII: 059QF0KO0R)  
Hamamelis Virginiana Top Water (UNII: NT00Y05A2V)  
Glycerin (UNII: PDC6A3C0OX)  
C13-14 Isoparaffin (UNII: E4F12ROE70)  
Cyclomethicone 5 (UNII: 0THT5PCI0R)  
Alcohol (UNII: 3K9958V90M)  
Laureth-7 (UNII: Z95S6G8201)  
Phenoxyethanol (UNII: HIE492ZZ3T)  
Cetyl Lactate (UNII: A7EVH2RK4O)  
PPG-2 Isoceteth-20 Acetate (UNII: BI6C7YO419)  
Cocamidopropyl PG-Dimonium Chloride Phosphate (UNII: H2KVQ74JM4)  
Polysorbate 20 (UNII: 7T1F30V5YH)  
Propylene Glycol (UNII: 6DC9Q167V3)  
Benzalkonium Chloride (UNII: F5UM2KM3W7)  
Ammonia (UNII: 5138Q19F1X)  
Edetate Sodium (UNII: MP1J8420LU)  
Butylene Glycol (UNII: 3XUS85K0RA)  
Capryloyl Glycine (UNII: 8TY5YO42NJ)  
Sarcosine (UNII: Z711V88R5F)  
Cinnamon Bark Oil (UNII: XE54U569EC)  
Purslane (UNII: M6S840WXG5)  
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
115 mL in 1 TUBE; Type 0: Not a Combination Product
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC MONOGRAPH FINALpart333D05/09/2012
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC MONOGRAPH FINALpart333D05/09/201211/01/2017
Labeler - Johnson & Johnson Consumer Inc. (002347102)

Revised: 11/2015
 
Johnson & Johnson Consumer Inc.