Label: AMOXI-MAST- amoxicillin suspension

LACTATING COW FORMULA
(FÓRMULA PARA VACAS LACTANTES)

Intramammary Infusion
(Infusión intramamaria)

CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Amoxi-Mast (amoxicillin intramammary infusion) is specially prepared for the treatment of bovine mastitis in lactating cows.

DESCRIPTION: Amoxi-Mast is a stable, nonirritating suspension of amoxicillin trihydrate containing the equivalent of 62.5 mg of amoxicillin per disposable syringe. Amoxi-Mast is manufactured by a nonsterilizing process.

Amoxicillin trihydrate is a semisynthetic penicillin derived from the penicillin nucleus, 6-amino-penicillanic acid. Chemically, it is d(-)-α-amino-p-hydroxybenzyl penicillin trihydrate.

ACTION: Amoxicillin trihydrate is bactericidal in action against susceptible organisms. It is a broad-spectrum antibiotic which is effective against common infectious mastitis pathogens, namely Streptococcus agalactiae and penicillin-sensitive Staphylococcus aureus.

In vitro studies have demonstrated the susceptibility of the following strains of bacteria: α- and β-haemolytic streptococci, nonpenicillinase-producing staphylococci, and Escherichia coli. Susceptibility has not been demonstrated against penicillinase-producing bacteria, particularly resistant staphylococci. Most strains of Pseudomonas, Klebsiella, and Enterobacter are resistant. The clinical or subclinical significance of these in vitro studies is not known.

INDICATIONS: Amoxi-Mast is indicated in the treatment of subclinical infectious bovine mastitis in lactating cows due to Streptococcus agalactiae and penicillin-sensitive Staphylococcus aureus. Early detection and treatment of mastitis is advised.

PRECAUTION: Because it is a derivative of 6-amino-penicillanic acid, Amoxi-Mast has the potential for producing allergic reactions. Such reactions are rare; however, should they occur, the subject should be treated with the usual agents (antihistamines, pressor amines).

DOSAGE AND ADMINISTRATION: Milk out udder completely. Wash udder and teats thoroughly with warm water containing a suitable dairy antiseptic. Dry thoroughly. Clean and disinfect the teat with alcohol swabs provided in the carton. Remove the syringe tip cover and insert the tip of the syringe into the teat orifice. Express the suspension into the quarter with gentle and continuous pressure. Withdraw the syringe and grasp the end of the teat firmly. Massage the medication up into the milk cistern.

For optimum response, the drug should be administered by intramammary infusion in each infected quarter as described above. Treatment should be repeated at 12-hour intervals for a total of 3 doses. At the next routine milking after the last dose, the treated quarter should be milked out and the milk discarded.

Each carton contains 12 alcohol swabs to facilitate proper cleaning and disinfecting of the teat orifice.

HOW SUPPLIED: Amoxi-Mast is supplied in cartons of 12 single-dose syringes with 12 alcohol swabs. Each 10-mL, disposable syringe contains amoxicillin trihydrate equivalent to 62.5 mg of amoxicillin activity.

Approved by FDA under NADA # 055-100

Manufactured by:
G.C. Hanford Mfg. Co.
Syracuse, NY 13201

Copyright © 2022 Merck & Co., Inc.,
Rahway, NJ, USA and its affiliates.
All rights reserved.

Rev 10/2022

INS15427 04

Amoxi-Mast®
(amoxicillin intramammary infusion)

LACTATING COW FORMULA

Intramammary Infusion

short tip

60-HOUR MILKOUT

Caution: Federal law restricts this drug to use by
or on the order of a licensed veterinarian.

12 single-dose (10 mL),
disposable syringes

Approved by FDA under NADA # 055-100

MERCK
Animal Health